Patents by Inventor Alexandre LARIVEE
Alexandre LARIVEE has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20250019380Abstract: The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of PI3K? enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with PI3K? signaling with the compounds and compositions of the disclosure.Type: ApplicationFiled: July 13, 2022Publication date: January 16, 2025Inventors: Alessandro BOEZIO, Alexander M. TAYLOR, Cary Griffin FRIDRICH, Hakan GUNAYDIN, Lucian V. DIPIETRO, Levi Charles Thomas PIERCE, Mary M. MADER, Ravi KURUKULASURIYA, Thomas H. MCLEAN, Yue PAN, Michael Paul DENINNO, Alexandre LARIVEE, Andrew j. BURNIE, Caleb MEDENA, Gaetan MAERTENS, Kashif TANVEER, Mohan PAL, Tarek MOHAMED, Thomas LEPITRE, Bren-Jordan ATIENZA, Naresh VEMULA, Shorena GELOZIA
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Publication number: 20240287058Abstract: The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of PI3K-? enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with PI3K-? signaling with the compounds and compositions of the disclosure.Type: ApplicationFiled: April 29, 2021Publication date: August 29, 2024Inventors: Alessandro BOEZIO, Lucian V. DIPIETRO, Cary Griffin FRIDRICH, Hakan GUNAYDIN, Ravi KURUKULASURIYA, André LESCARBEAU, Mary M. MADER, Thomas H. MCLEAN, Levi CharlesThomas PIERCE, Kevin David RAYNOR, Kelley C. SHORTSLEEVES, Yong TANG, Alexander M. TAYLOR, W. Patrick WALTERS, Hanmo ZHANG, Fabrizio GIORDANETTO, Yakov PECHERSKY, Qi WANG, Bren-Jordan ATIENZA, Megan BERTRAND-LAPERLE, Andrew J. BURNIE, Fei CHEN, Sampada CHITALE, Shorena GELOZIA, Jean-Benoit GIGUERE, Elodie LANDAGARAY, Alexandre LARIVEE, Thomas LEPITRE, Gaetan MAERTENS, Johanne OUTIN, Mohan PAL, Claudio STURINO, Kashif TANVEER, Rakesh THORAT, Naresh VEMULA, Elaine B. KRUEGER, Yue PAN, Michael Paul DENINNO, Yves BOUSQUET, Antoine JOBIN-DES LAURIERS, Jessica LEE, Tarek MOHAMED
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Publication number: 20230355813Abstract: Systems and methods for heteroaromatic silicon fluoride compounds as radiopharmaceuticals with theranostic properties are described. The theranostic heteroaromatic silicon fluoride compounds can be conjugated with various disease binding ligands and/or chelators for imaging and therapeutic applications.Type: ApplicationFiled: April 20, 2023Publication date: November 9, 2023Applicant: Fuzionaire Diagnostics, Inc.Inventors: Christopher Martin Waldmann, Thomas A. Singleton, Anton A. Toutov, Carl Daniel Estrada, Prashant Suresh Deore, Julie Delecueillerie, Patrick DeRoy, Alexandre Larivée, Alexey Kostikov, Jean-Philip George Lumb, HyunJune Jun, En Zhao, Ryan Christopher Clark, Burhan Ahmed Hussein, Bren Jordan Perez Atienza
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Publication number: 20230353959Abstract: The present disclosure relates to novel compounds and pharmaceutical compositions thereof, and methods for inhibiting the activity of PI3K-? enzymes with the compounds and compositions of the disclosure. The present disclosure further relates to, but is not limited to, methods for treating disorders associated with PI3K-? signaling with the compounds and compositions of the disclosure.Type: ApplicationFiled: June 9, 2023Publication date: November 2, 2023Inventors: Lucian V. DIPIETRO, Kelley C. SHORTSLEEVES, Thomas H. MCLEAN, Alexandre LARIVEE, Fabrizio GIORDANETTO
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Publication number: 20230113202Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of GPR84, and the treatment of GPR84-mediated disorders.Type: ApplicationFiled: February 2, 2022Publication date: April 13, 2023Inventors: Shaun ABBOTT, Mylène DeLESELEUC, Julien MARTEL, Elyse BOURQUE, Jeremy GREEN, Alexandre LARIVÉE, Jean-Benoìt GIGUÈRE, Elodie LANDAGARAY, Claudio STURINO, Nadia Michel NASSER
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Publication number: 20230091528Abstract: The present invention provides compounds, compositions thereof, and methods of using the same for the inhibition of GPR84, and the treatment of GPR84-mediated disorders.Type: ApplicationFiled: February 2, 2022Publication date: March 23, 2023Inventors: Shaun ABBOTT, Mylène DeLESELEUC, Julien MARTEL, Elyse BOURQUE, Jeremy GREEN, Alexandre LARIVÉE, Jean-Benoît GIGUÈRE, Elodie LANDAGARAY, Claudio STURINO
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Publication number: 20220024900Abstract: Bifunctional compounds that increase uric acid excretion and reduce uric acid production, and monofunctional compounds that either increase uric acid excretion or reduce uric acid production. Methods of using these compounds for reducing uric acid levels in blood or serum, for treating disorders of uric acid metabolism, and for maintaining normal uric acid levels in blood or serum are also provided. Pharmaceutical compositions comprising the bifunctional and monofunctional compounds are also provided.Type: ApplicationFiled: October 5, 2021Publication date: January 27, 2022Applicant: Acquist LLCInventors: John J. Piwinski, Ronald N. Buckle, Alexandre Larivée, Arshad Siddiqui, Raymond P. Warrell, JR.
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Patent number: 11168075Abstract: Bifunctional compounds that increase uric acid excretion and reduce uric acid production, and monofunctional compounds that either increase uric acid excretion or reduce uric acid production. Methods of using these compounds for reducing uric acid levels in blood or serum, for treating disorders of uric acid metabolism, and for maintaining normal uric acid levels in blood or serum are also provided. Pharmaceutical compositions comprising the bifunctional and monofunctional compounds are also provided.Type: GrantFiled: July 14, 2020Date of Patent: November 9, 2021Assignee: Acquist LLCInventors: John J. Piwinski, Ronald N. Buckle, Alexandre Larivée, Arshad Siddiqui, Raymond P. Warrell, Jr.
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Publication number: 20210236495Abstract: Bifunctional compounds that increase uric acid excretion and reduce uric acid production, and monofunctional compounds that either increase uric acid excretion or reduce uric acid production. Methods of using these compounds for reducing uric acid levels in blood or serum, for treating disorders associated with excess uric acid, and for maintaining normal uric acid levels in blood or serum, or the whole body, are also provided. Pharmaceutical compositions comprising the bifunctional and monofunctional compounds are also provided.Type: ApplicationFiled: April 21, 2021Publication date: August 5, 2021Applicant: Acquist LLCInventors: Raymond P. Warrell, JR., John J. Piwinski, Alexandre Larivée, Arshad Siddiqui, Karen Thai
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Patent number: 11020397Abstract: Bifunctional barbiturate-derivative compounds that increase uric acid excretion and reduce uric acid production, and monofunctional barbiturate-derivative compounds that either increase uric acid excretion or reduce uric acid production are provided. Methods of using these compounds for reducing uric acid levels in blood or serum, for treating disorders associated with excess uric acid, and for maintaining normal uric acid levels in blood or serum, or the whole body, are also provided. Pharmaceutical compositions comprising the bifunctional and monofunctional compounds are also provided.Type: GrantFiled: May 12, 2020Date of Patent: June 1, 2021Assignee: Acquist LLCInventors: Raymond P. Warrell, Jr., John J. Piwinski, Alexandre Larivée, Arshad Siddiqui, Karen Thai
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Publication number: 20200347034Abstract: Bifunctional compounds that increase uric acid excretion and reduce uric acid production, and monofunctional compounds that either increase uric acid excretion or reduce uric acid production. Methods of using these compounds for reducing uric acid levels in blood or serum, for treating disorders of uric acid metabolism, and for maintaining normal uric acid levels in blood or serum are also provided. Pharmaceutical compositions comprising the bifunctional and monofunctional compounds are also provided.Type: ApplicationFiled: July 14, 2020Publication date: November 5, 2020Applicant: Acquist LLCInventors: John J. Piwinski, Ronald N. Buckle, Alexandre Larivée, Arshad Siddiqui, Raymond P. Warrell, JR.
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Patent number: 10759784Abstract: Bifunctional compounds that increase uric acid excretion and reduce uric acid production, and monofunctional compounds that either increase uric acid excretion or reduce uric acid production. Methods of using these compounds for reducing uric acid levels in blood or serum, for treating disorders of uric acid metabolism, and for maintaining normal uric acid levels in blood or serum are also provided. Pharmaceutical compositions comprising the bifunctional and monofunctional compounds are also provided.Type: GrantFiled: June 21, 2017Date of Patent: September 1, 2020Assignee: Acquist LLCInventors: John J. Piwinski, Ronald N. Buckle, Alexandre Larivée, Arshad Siddiqui, Raymond P. Warrell, Jr.
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Publication number: 20200268757Abstract: Bifunctional compounds that increase uric acid excretion and reduce uric acid production, and monofunctional compounds that either increase uric acid excretion or reduce uric acid production. Methods of using these compounds for reducing uric acid levels in blood or serum, for treating disorders associated with excess uric acid, and for maintaining normal uric acid levels in blood or serum, or the whole body, are also provided. Pharmaceutical compositions comprising the bifunctional and monofunctional compounds are also provided.Type: ApplicationFiled: May 12, 2020Publication date: August 27, 2020Applicant: Acquist LLCInventors: Raymond P. Warrell, JR., John J. Piwinski, Alexandre Larivée, Arshad Siddiqui, Karen Thai
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Publication number: 20200197393Abstract: Bifunctional compounds that increase uric acid excretion and reduce uric acid production, and monofunctional compounds that either increase uric acid excretion or reduce uric acid production. Methods of using these compounds for reducing uric acid levels in blood or serum, for treating disorders associated with excess uric acid, and for maintaining normal uric acid levels in blood or serum, or the whole body, are also provided. Pharmaceutical compositions comprising the bifunctional and monofunctional compounds are also provided.Type: ApplicationFiled: December 20, 2018Publication date: June 25, 2020Inventors: Raymond P. Warrell, JR., John J. Piwinski, Alexandre Larivée, Arshad Siddiqui, Karen Thai
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Patent number: 10688095Abstract: Bifunctional barbiturate-derivative compounds that increase uric acid excretion and reduce uric acid production, and monofunctional barbiturate-derivative compounds that either increase uric acid excretion or reduce uric acid production are provided. Methods of using these compounds for reducing uric acid levels in blood or serum, for treating disorders associated with excess uric acid, and for maintaining normal uric acid levels in blood or serum, or the whole body, are also provided. Pharmaceutical compositions comprising the bifunctional and monofunctional compounds are also provided.Type: GrantFiled: December 20, 2018Date of Patent: June 23, 2020Assignee: Acquist LLCInventors: Raymond P. Warrell, Jr., John J. Piwinski, Alexandre Larivée, Arshad Siddiqui, Karen Thai
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Publication number: 20200017477Abstract: Bifunctional compounds that increase uric acid excretion and reduce uric acid production, and monofunctional compounds that either increase uric acid excretion or reduce uric acid production. Methods of using these compounds for reducing uric acid levels in blood or serum, for treating disorders of uric acid metabolism, and for maintaining normal uric acid levels in blood or serum are also provided. Pharmaceutical compositions comprising the bifunctional and monofunctional compounds are also provided.Type: ApplicationFiled: June 21, 2017Publication date: January 16, 2020Inventors: John J. Piwinski, Ronald N. Buckle, Alexandre Larivée, Arshad Siddiqui, Raymond P. Warrell, JR.
