Abstract: The present disclosure provides transmembrane chimeric proteins derived from transposable element (TE)-exon fusion transcripts, as well as nucleic acids, antibodies, CARs, non-HLA restricted TCR and immune cells targeting such chimeric proteins that can be used in cancer therapy.

Abstract: The present disclosure relates to a pixel comprising: a photodiode comprising a portion of a substrate of a semiconductor material, extending vertically from a first face of the substrate to a second face of the substrate configured to receive light; a layer of a first material covering each of the lateral surfaces of the portion; a layer of a second material covering the portion on the side of the first face, first and second material having refractive indexes lower than that of the semiconductor material; and a diffractive structure disposed on a face of the photodiode on the side of the second face.

Abstract: The present disclosure relates to a pixel comprising: a photodiode comprising a portion of a substrate of a semiconductor material, extending vertically from a first face of the substrate to a second face of the substrate configured to receive light; a layer of a first material covering each of the lateral surfaces of the portion; a layer of a second material covering the portion on the side of the first face, first and second material having refractive indexes lower than that of the semiconductor material; and a diffractive structure disposed on a face of the photodiode on the side of the second face.

Abstract: A single photon avalanche diode (SPAD) includes a PN junction in a semiconductor well doped with a first type of dopant. The PN junction is formed between a first region doped with the first type of dopant and a second region doped with a second type of dopant opposite to the first type of dopant. The first doped region is shaped so as to incorporate local variations in concentration of dopants that are configured, in response to a voltage between the second doped region and the semiconductor well that is greater than or equal to a level of a breakdown voltage of the PN junction, to generate a monotonic variation in the electrostatic potential between the first doped region and the semiconductor well.

Abstract: A single photon avalanche diode (SPAD) includes a PN junction in a semiconductor well doped with a first type of dopant. The PN junction is formed between a first region doped with the first type of dopant and a second region doped with a second type of dopant opposite to the first type of dopant. The first doped region is shaped so as to incorporate local variations in concentration of dopants that are configured, in response to a voltage between the second doped region and the semiconductor well that is greater than or equal to a level of a breakdown voltage of the PN junction, to generate a monotonic variation in the electrostatic potential between the first doped region and the semiconductor well.

Abstract: A device includes a single photon avalanche diode in a portion of a substrate, wherein the portion has an octagonal profile. The octagonal profile is delimited by a wall forming an octagonal contour around the portion. The device further includes an array of diodes, wherein each diode is located in a corner between four adjacent single photon avalanche diodes. Each single photon avalanche diode further includes a doped anode region. A shallow trench isolation is formed in each doped anode region. A polysilicon line forming a resistor is supported at the upper surface of the shallow trench isolation.

Abstract: A device includes a single photon avalanche diode in a substrate and a resistor. The resistor is provided resting on an insulating trench located in a doped anode region of the single photon avalanche diode.

Abstract: Method and System for avoiding howling disturbance especially on conferences, wherein the method comprising the steps of using a howling detector unit implemented inside a multipoint control unit to receive an audio stream input from a client, analyzing the audio input with the howling detector in order to verify if howling noise is present, using at least two of a skewness analysis, a flatness analysis, a crest analysis, a rolloff analysis and preventing the audio stream input to be forwarded as an output to an audio mixer, if howling noise is present.

Abstract: Method and System for avoiding howling disturbance especially on conferences, wherein the method comprising the steps of using a howling detector unit implemented inside a multipoint control unit to receive an audio stream input from a client, analyzing the audio input with the howling detector in order to verify if howling noise is present, using at least two of a skewness analysis, a flatness analysis, a crest analysis, a rolloff analysis and preventing the audio stream input to be forwarded as an output to an audio mixer, if howling noise is present.

Abstract: A method of determining the quality of transmitted voice data can include: providing voice data at a transmitter side in a first data format, providing a first test signal in the first data format, combining the voice data and the test signal to form input data, transmitting the input data in a transmittal data format, receiving the transmitted input data at a receiver side to obtain output data, removing at least portions of a data packet in the output data or of a data packet derived therefrom in order to derive a second test signal, and analysing the derived second test signal by applying a predetermined analysis criterion in order to obtain at least one value for a quality indicator. An apparatus and system can also be configured to utilize embodiments of the method.

Abstract: A single photon avalanche diode (SPAD) includes a PN junction in a semiconductor well doped with a first type of dopant. The PN junction is formed between a first region doped with the first type of dopant and a second region doped with a second type of dopant opposite to the first type of dopant. The first doped region is shaped so as to incorporate local variations in concentration of dopants that are configured, in response to a voltage between the second doped region and the semiconductor well that is greater than or equal to a level of a breakdown voltage of the PN junction, to generate a monotonic variation in the electrostatic potential between the first doped region and the semiconductor well.

Abstract: Disclosed herein is a method comprising: exposing an organ to be transplanted to an aqueous solution comprising: sodium (Na+) ions at a concentration between 30 and 150 mmol·L?1; potassium ions (K+) at a concentration between 10 and 40 mmol·L?1; polyethylene glycol with a molecular weight of 35,000 g·mol?1 (PEG 35000) at a concentration between 2 and 5 g·L?1, wherein the step of exposing further comprises preserving and/or rinsing and/or reconditioning the organ in the aqueous solution.

Abstract: The present disclosure relates to a pixel comprising: a photodiode comprising a portion of a substrate of a semiconductor material, extending vertically from a first face of the substrate to a second face of the substrate configured to receive light; a layer of a first material covering each of the lateral surfaces of the portion; a layer of a second material covering the portion on the side of the first face, first and second material having refractive indexes lower than that of the semiconductor material; and a diffractive structure disposed on a face of the photodiode on the side of the second face.

Abstract: This invention relates to an aqueous solution for preserving and rinsing organs to be transplanted comprising: sodium (Na+) ions at a concentration between 30 and 150 mmol·L?1; potassium ions (K+) at a concentration between 10 and 40 mmol·L?1; polyethylene glycol with a molecular weight of 35,000 g·mol-1 (PEG 35000) at a concentration between 2 and 5 g·L?1.

Abstract: A method of determining the quality of transmitted voice data can include: providing voice data at a transmitter side in a first data format, providing a first test signal in the first data format, combining the voice data and the test signal to form input data, transmitting the input data in a transmittal data format, receiving the transmitted input data at a receiver side to obtain output data, removing at least portions of a data packet in the output data or of a data packet derived therefrom in order to derive a second test signal, and analysing the derived second test signal by applying a predetermined analysis criterion in order to obtain at least one value for a quality indicator. An apparatus and system can also be configured to utilize embodiments of the method.

Abstract: This invention relates to an aqueous solution for preserving and rinsing organs to be transplanted comprising: sodium (Na+) ions at a concentration between 30 and 150 mmol.L?1; potassium ions (K+) at a concentration between 10 and 40 mmol.L?1; polyethylene glycol with a molecular weight of 35,000 g.mo1-1 (PEG 35000) at a concentration between 2 and 5 g.L?1.

Abstract: A method for assessing quality of a video transmission over a network between a transmitting side and a receiving side can include receiving, at the receiving side, a video stream generated at the transmitting side and transmitted via the network to the receiving side including a plurality of frames. At least one of the frames can include synthetically created portions. At the receiving side, the video stream received from the transmitting side can be analyzed by comparing the video stream received with the video stream originally transmitted. The receiving side can also generate and output a quality score for the video stream received. The output score can be based on the performed analysis. A system and communication apparatus configured to utilize an embodiment of the method are also provided.

Abstract: A system and method for selecting a communication connection candidate for transmission of a media stream via a media connection over a communications network can include use of the ICE protocol for selecting a transmission communication connection candidate for transmitting the media stream from a local peer to a remote peer. During transmission of the media stream from the local peer to the remote peer via the selected transmission communication connection candidate, the communication connection candidates can be tested with respect to Quality of Service (QoS), in both communication directions. The QoS of at least one tested communication connection candidate can be compared to the QoS of the selected communication connection candidate transmitting the media stream. If a tested communication connection candidate provides a better QoS, then the transmission of the media stream can be switched to that communication connection candidate.

Abstract: A system and method for selecting a communication connection candidate for transmission of a media stream via a media connection over a communications network can include use of the ICE protocol for selecting a transmission communication connection candidate for transmitting the media stream from a local peer to a remote peer. During transmission of the media stream from the local peer to the remote peer via the selected transmission communication connection candidate, the communication connection candidates can be tested with respect to Quality of Service (QoS), in both communication directions. The QoS of at least one tested communication connection candidate can be compared to the QoS of the selected communication connection candidate transmitting the media stream. If a tested communication connection candidate provides a better QoS, then the transmission of the media stream can be switched to that communication connection candidate.

Abstract: A method for assessing quality of a video transmission over a network between a transmitting side and a receiving side can include receiving, at the receiving side, a video stream generated at the transmitting side and transmitted via the network to the receiving side including a plurality of frames. At least one of the frames can include synthetically created portions. At the receiving side, the video stream received from the transmitting side can be analyzed by comparing the video stream received with the video stream originally transmitted. The receiving side can also generate and output a quality score for the video stream received. The output score can be based on the performed analysis. A system and communication apparatus configured to utilize an embodiment of the method are also provided.