Patents by Inventor Alexandre Mebazaa

Alexandre Mebazaa has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240100071
    Abstract: Subject matter of the present invention is a combination medication for use in the treatment of a patient having acute and/or persistent dyspnea comprising at least two of the following components: a beta blocker, and one agent of the group consisting of an angiotensin-converting enzyme (ACE) inhibitor, an angiotensin II inhibitor and a combination of angiotensin II inhibitor or an angiotensin receptor-neprilysin inhibitor (ARNi), and mineralo receptor antagonist (MRA), gliflozine, a loop-acting diuretic, wherein a sample of bodily fluid of said patient has a level of BNP>200 pg/mL and/or has a level NT-proBNP>600 pg/mL, and wherein said sample of bodily fluid is selected from the group comprising blood, plasma and serum, and wherein said patient is either a patient with heart failure with left ventricular ejection fraction (LVEF) greater and equal to 40%, preferably 50%, or a patient with no heart failure.
    Type: Application
    Filed: December 15, 2021
    Publication date: March 28, 2024
    Applicant: S-Form Pharma
    Inventors: Eric HALIOUA, Marcio SCORSIN, Alexandre MEBAZAA
  • Patent number: 11638529
    Abstract: The present invention relates in particular to the field of anesthesia and to a method for real-time evaluation of the mean arterial pressure of a patient from plethysmography measurements. It also relates to a method for treating a patient comprising by continuously evaluating the mean arterial pressure of the patient, based on values continuously calculated by plethysmography.
    Type: Grant
    Filed: December 21, 2018
    Date of Patent: May 2, 2023
    Assignee: ASSISTANCE PUBLIQUE—HOPITAUX DE PARIS
    Inventors: Fabrice Vallée, Jona Joachim, Maxime Coutrot, Joaquim Mateo, Étienne Gayat, Alexandre Mebazaa
  • Publication number: 20200390347
    Abstract: The present invention relates in particular to the field of anesthesia and to a method for real-time evaluation of the mean arterial pressure of a patient from plethysmography measurements.
    Type: Application
    Filed: December 21, 2018
    Publication date: December 17, 2020
    Inventors: Fabrice VALLÉE, Jona JOACHIM, Maxime COUTROT, Joaquim MATEO, Étienne GAYAT, Alexandre MEBAZAA
  • Publication number: 20180321257
    Abstract: The present invention concerns the use of CD146 as a marker of the vascular wall tension, especially for diagnosing, predicting and/or prognosticating diseases associated with variations of the vessel wall tension.
    Type: Application
    Filed: November 7, 2016
    Publication date: November 8, 2018
    Inventors: Alexandre Mebazaa, Mattia Arrigo
  • Patent number: 8784313
    Abstract: Novel prognosis methods associated with cases of postpartum haemorrhage providing a predictive test enabling practitioners to provide better management of patients suffering from postpartum haemorrhage. Different risk factors exist on which a score allowing prediction of the need to carry out invasive procedures to stop bleeding has been developed.
    Type: Grant
    Filed: August 6, 2009
    Date of Patent: July 22, 2014
    Assignee: Assistance Publique—Hopitaux de Paris
    Inventors: Alexandre Mebazaa, Etienne Gayat, Matthieu Resche-Rigon, Olivier Morel, Yann Fargeaudou, Matthias Rossignol, Didier Payen
  • Publication number: 20130190585
    Abstract: The present invention relates to an in vitro method of prognosis for the arrest of bleeding in a patient suffering from postpartum haemorrhage in the absence of an invasive procedure, comprising the following steps: (a) determining, using a biological sample from said patient, the plasma fibrinogen concentration, the blood troponin concentration and also the prothrombin time; (b) studying at least two clinical markers for said patient, selected from the group comprising heart rate and the presence of placentation abnormalities; (c) calculating a score Z according to the following equation: Z=a+b+v+d+e; where a is associated with the existence of placentation abnormalities in said patient, with a being 0 when no placentation abnormality is observed in said patient and a being 1 when one or more placentation abnormalities are observed in said patient; where b is associated with the heart rate of said patient, with b being 0 when the heart rate of said patient is less than or equal to 115 bpm (beats per minute)
    Type: Application
    Filed: August 6, 2009
    Publication date: July 25, 2013
    Inventors: Alexandre Mebazaa, Etienne Gayat, Matthieu Resche-Rigon, Olivier Morel, Yann Fargeaudou, Matthias Rossignol, Didier Payen