Patents by Inventor Alexandre Nesterov

Alexandre Nesterov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Identifying Modulators of Insect Transient Receptor Potential Channels
    Publication number: 20230176038
    Abstract: The present invention relates to a screening method for determining whether or not a candidate compound is a modulator of a complex consisting of the insect transient receptor potential channel Nanchung protein and the insect transient receptor potential channel Water witch protein. The present invention further relates to a screening method for determining whether or not a candidate compound directly binds to the complex consisting of the Nanchung protein and Water witch protein. The present invention further relates to a screening method for determining whether or not a candidate compound is a modulator of the insect Water witch protein. The present invention further provides a method of insect control by applying an insect-specific TRP channel modulator determined by the screening method. The present invention further provides a method of classifying an insecticide compound by its mode of action using the binding assay and/or a functional assay.
    Type: Application
    Filed: December 10, 2020
    Publication date: June 8, 2023
    Inventors: Alexandre NESTEROV, Ramani KANDASAMY, Lynn F. STAM
  • Methods for Identifying Compounds that Directly Bind to Insect Transient Receptor Potential Channels
    Publication number: 20180220653
    Abstract: The present invention relates to a screening method for determining whether or not a candidate compound directly binds to an insect transient receptor potential V (TRPV) channel. The present invention further provides a method of identifying a compound that directly binds to a Nanchung protein, TRP and/or TRPV protein and/or channel using, a binding assay. The present invention further provides a method of classifying an insecticide compound by its mode of action using the binding assay and/or a functional assays.
    Type: Application
    Filed: June 17, 2016
    Publication date: August 9, 2018
    Inventors: Alexandre Nesterov, Ramani Kandasamy, Wolfgang von Deyn, Damian London, Katherine Lelito, Vincent L Salgado
  • Methods for determining modulators of insect transient receptor potential V (TRPV) channel
    Patent number: 10024845
    Abstract: The present invention relates to a screening method for determining whether or not a candidate compound is a modulator of an insect transient receptor potential V (TRPV) channel. The present invention further provides a method of insect control by applying to an insect-specific TRPV channel modulator determined by the screening method. The present invention further relates to an expression vector that includes a nucleic acid molecule coding for an insect TRPV channel. Also, the present invention relates to cell that includes the expression vector encoding a TRPV channel.
    Type: Grant
    Filed: December 19, 2014
    Date of Patent: July 17, 2018
    Inventors: Alexandre Nesterov, Ramani Kandasamy, Barbara Wedel, Vincent L Salgado
  • Methods for Determining Modulators of Insect Transient Receptor Potential V (TRPV) Channel
    Publication number: 20170003279
    Abstract: The present invention relates to a screening method for determining whether or not a candidate compound is a modulator of an insect transient receptor potential V (TRPV) channel. The present invention further provides a method of insect control by applying to an insect-specific TRPV channel modulator determined by the screening method. The present invention further relates to an expression vector that includes a nucleic acid molecule coding for an insect TRPV channel. Also, the present invention relates to cell that includes the expression vector encoding a TRPV channel.
    Type: Application
    Filed: December 19, 2014
    Publication date: January 5, 2017
    Applicant: BASF SE
    Inventors: Alexandre Nesterov, Ramani Kandasamy, Barbara Wedel, Vincent L Salgado