Abstract: Some embodiments relate to an attachment system for attaching at least one panel to a supporting structure that includes at least one girder extending in a first direction, the girder including a holding rim and a surface for bearing the panel thereon. The system includes a flange, a clamp and a clamping assembly linking the flange to the clamp, which are arranged so as to sandwich, during assembly, the holding rim of the girder with the panel so that they bear on the bearing surface of the girder. The clamp includes a first series of teeth projecting towards the flange in a manner substantially parallel to an axis of the clamping assembly. The teeth are to engage, via gripping, with the holding rim of the girder during assembly.

Abstract: Novel antibodies directed against Dual Ig domain containing cell adhesion molecule (DICAM) are described. These anti-DICAM antibodies are capable of detecting DICAM by Western blot and/or flow cytometry, blocking the interaction between DICAM and its ligand ?V?3 integrin, and/or blocking the migration of inflammatory cytokine-secreting TH17 lymphocytes across the blood brain barrier. Uses of these antibodies or compositions comprising same for the diagnosis, prevention and/or treatment of autoimmune/inflammatory conditions, such as neuroinflammatory conditions, and for the targeting, identification and selection of inflammatory cytokine-secreting TH17 lymphocytes or precursor thereof are also disclosed.

Abstract: Some embodiments relate to an attachment system for attaching at least one panel to a supporting structure that includes at least one girder extending in a first direction, the girder including a holding rim and a surface for bearing the panel thereon. The system includes a flange, a clamp and a clamping assembly linking the flange to the clamp, which are arranged so as to sandwich, during assembly, the holding rim of the girder with the panel so that they bear on the bearing surface of the girder. The clamp includes a first series of teeth projecting towards the flange in a manner substantially parallel to an axis of the clamping assembly. The teeth are to engage, via gripping, with the holding rim of the girder during assembly.

Abstract: Novel antibodies directed against Dual Ig domain containing cell adhesion molecule (DICAM) are described. These anti-DICAM antibodies are capable of detecting DICAM by Western blot and/or flow cytometry, blocking the interaction between DICAM and its ligand ?V?3 integrin, and/or blocking the migration of inflammatory cytokine-secreting TH17 lymphocytes across the blood brain barrier. Uses of these antibodies or compositions comprising same for the diagnosis, prevention and/or treatment of autoimmune/inflammatory conditions, such as neuroinflammatory conditions, and for the targeting, identification and selection of inflammatory cytokine-secreting TH17 lymphocytes or precursor thereof are also disclosed.

Abstract: Methods, uses, agents and compositions useful for the diagnosis, prevention and/or treatment of inflammatory conditions, such as neuroinflammatory conditions such as multiple sclerosis, and for the identification and selection of inflammatory cytokine-secreting T cell or a precursor thereof, based on the expression and/or modulation of melanoma cell adhesion molecule (MCAM) are disclosed.

Abstract: Methods, uses, agents and compositions useful for the diagnosis, prevention and/or treatment of inflammatory conditions, such as neuroinflammatory conditions such as multiple sclerosis, and for the identification and selection of inflammatory cytokine-secreting T cell or a precursor thereof, based on the expression and/or modulation of melanoma cell adhesion molecule (MCAM) are disclosed.

Abstract: Methods, uses, agents and compositions useful for the prevention, treatment and/or diagnosis of neuroinflammatory conditions such as multiple sclerosis and spinal cord injury based on the modulation of nerve injury-induced protein-1 (Ninjurin-1) are disclosed.

Abstract: Methods, uses, agents and compositions useful for the diagnosis, prevention and/or treatment of inflammatory conditions, such as neuroinflammatory conditions such as multiple sclerosis, and for the identification and selection of inflammatory cytokine-secreting T cell or a precursor thereof, based on the expression and/or modulation of melanoma cell adhesion molecule (MCAM) are disclosed.

Abstract: Methods, uses, agents and compositions useful for the diagnosis, prevention and/or treatment of inflammatory conditions, such as neuroinflammatory conditions such as multiple sclerosis, and for the identification and selection of inflammatory cytokine-secreting T cell or a precursor thereof, based on the expression and/or modulation of melanoma cell adhesion molecule (MCAM) are disclosed.

Abstract: Methods, uses, agents and compositions useful for the diagnosis, prevention and/or treatment of inflammatory conditions, such as neuroinflammatory conditions such as multiple sclerosis, and for the identification and selection of inflammatory cytokine-secreting T cell or a precursor thereof, based on the expression and/or modulation of melanoma cell adhesion molecule (MCAM) are disclosed.

Abstract: Methods, uses, agents and compositions useful for the prevention, treatment and/or diagnosis of neuroinflammatory conditions such as multiple sclerosis and spinal cord injury based on the modulation of nerve injury-induced protein-1 (Ninjurin-1) are disclosed.