Abstract: A system (100) for providing a normalised microcirculatory resistance value for a vessel (110), is provided. The system includes one or more processors (120) configured to: compute (S110) a microcirculatory resistance value for the vessel (110) based on a transit time (TT) taken for an injected bolus to travel between a proximal position (Posa) in the vessel, and a distal position (Posd) in the vessel; and divide (S120) the computed microcirculatory resistance value by a transit length (dT) representing a length of the vessel between the proximal position (Posa) and the distal position (Posd), to provide the normalised microcirculatory resistance value.

Abstract: A system (100) for determining flow parameters of a lumen (110) in a hyperemic state induced subsequent to a contrast agent injection (Inj 1) into the lumen in a basal state, is provided. The system comprising one or more processors (120) configured to: determine (S110), based on received angiographic data representing the injected contrast agent and/or received injector data representing the injected contrast agent, a temporal window (TH0, TH1) representing a duration of the induced hyperemic state; and output (S120) a signal (Sh) indicative of the temporal window (TH0, TH1).

Abstract: An ultrasound system includes a processor circuit in communication with an array of acoustic elements and a display. The processor circuit receives B-mode and/or Doppler ultrasound data representative of mitral regurgitation associated with an orifice in a mitral valve. The processor circuit generates a model of the orifice and outputs a graphical representation of the model of the orifice to the display. The processor circuit generates a blood flow model of the mitral regurgitation based on the model of the orifice. The processor circuit compares the blood flow model to the Doppler data. The processor circuit changes the model of the orifice (e.g., a different shape, a different position, and/or a different orientation) such that the blood flow model is changed to match the Doppler data. The processor circuit outputs a graphical representation of the orifice with the different shape, the different position, and/or the different orientation to the display.

Abstract: The invention provides a processor for use in a system for obtaining a blood flow velocity measurement based on an angiogram obtained from a subject. The angiogram is representative of a vessel including a contrast agent therein, and wherein the contrast agent has been provided to the vessel in bursts at a given average frequency, thereby providing contrast data within the angiogram. The processor generates a velocity curve representing the blood flow velocity within the vessel over the cardiac cycle based on an estimated period of the cardiac cycle, an estimated instantaneous blood flow velocity of each angiogram image frame, a calculated confidence value of each angiogram image frame and the estimated point within the cardiac cycle represented by each angiogram image frame.