Patents by Inventor Alexandre V. Nikolaitchik

Alexandre V. Nikolaitchik has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 7078554
    Abstract: Compositions and methods for determining the presence or concentration of glucose in a sample which may also contain an alpha-hydroxy acid or a beta-diketone. The method uses a compound having at least two recognition elements for glucose, oriented such that the interaction between the compound and glucose is more stable than the interaction between the compound and the alpha-hydroxy acid or beta-diketone, such that the presence of the alpha-hydroxy acid or the beta-diketone does not substantially interfere with said determination.
    Type: Grant
    Filed: October 4, 2004
    Date of Patent: July 18, 2006
    Assignee: Sensors for Medicine and Science, Inc.
    Inventors: George Y. Daniloff, Aristotle G. Kalivretenos, Alexandre V. Nikolaitchik
  • Patent number: 6800451
    Abstract: Compositions and methods for determining the presence or concentration of glucose in a sample which may also contain an alpha-hydroxy acid or a beta-diketone. The method uses a compound having at least two recognition elements for glucose, oriented such that the interaction between the compound and glucose is more stable than the interaction between the compound and the alpha-hydroxy acid or beta-diketone, such that the presence of the alpha-hydroxy acid or the beta-diketone does not substantially interfere with said determination.
    Type: Grant
    Filed: July 3, 2002
    Date of Patent: October 5, 2004
    Assignee: Sensors for Medicine and Science, Inc.
    Inventors: George Y. Daniloff, Aristotle G. Kalivretenos, Alexandre V. Nikolaitchik
  • Publication number: 20030082663
    Abstract: Compositions and methods for determining the presence or concentration of glucose in a sample which may also contain an alpha-hydroxy acid or a beta-diketone. The method uses a compound having at least two recognition elements for glucose, oriented such that the interaction between the compound and glucose is more stable than the interaction between the compound and the alpha-hydroxy acid or beta-diketone, such that the presence of the alpha-hydroxy acid or the beta-diketone does not substantially interfere with said determination.
    Type: Application
    Filed: July 3, 2002
    Publication date: May 1, 2003
    Inventors: George Y. Daniloff, Aristotle G. Kalivretenos, Alexandre V. Nikolaitchik
  • Publication number: 20020127626
    Abstract: Compositions and methods for determining the presence or concentration of glucose in a sample which may also contain an alpha-hydroxy acid or a beta-diketone. The method uses a compound having at least two recognition elements for glucose, oriented such that the interaction between the compound and glucose is more stable than the interaction between the compound and the alpha-hydroxy acid or beta-diketone, such that the presence of the alpha-hydroxy acid or the beta-diketone does not substantially interfere with said determination.
    Type: Application
    Filed: December 28, 2001
    Publication date: September 12, 2002
    Applicant: Sensors for Medicine and Science, Inc.
    Inventors: George Y. Daniloff, Aristotle G. Kalivretenos, Alexandre V. Nikolaitchik
  • Publication number: 20020119581
    Abstract: Disclosed are methods for detecting analytes with indicator systems which may undergo a molecular configurational change upon exposure to the analyte. The configurational change affects a detectable quality associated with the indicator system, thereby allowing detection of the presence or concentration of the analyte.
    Type: Application
    Filed: December 28, 2001
    Publication date: August 29, 2002
    Inventors: George Y. Daniloff, Aristotle G. Kalivretenos, Alexandre V. Nikolaitchik, Edwin F. Ullman
  • Publication number: 20020094586
    Abstract: Disclosed are methods for detecting analytes with indicator systems which may undergo a molecular configurational change upon exposure to the analyte. The configurational change affects a detectable quality associated with the indicator system, thereby allowing detection of the presence or concentration of the analyte.
    Type: Application
    Filed: January 5, 2001
    Publication date: July 18, 2002
    Applicant: Sensors for Medicine and Science, Inc.
    Inventors: George Y. Daniloff, Aristotle G. Kalivretenos, Alexandre V. Nikolaitchik, Edwin F. Ullman
  • Publication number: 20020090734
    Abstract: Compositions and methods for determining the presence or concentration of glucose in a sample which may also contain an alpha-hydroxy acid or a beta-diketone. The method uses a compound having at least two recognition elements for glucose, oriented such that the interaction between the compound and glucose is more stable than the interaction between the compound and the alpha-hydroxy acid or beta-diketone, such that the presence of the alpha-hydroxy acid or the beta-diketone does not substantially interfere with said determination.
    Type: Application
    Filed: January 5, 2001
    Publication date: July 11, 2002
    Inventors: George Y. Daniloff, Aristotle G. Kalivretenos, Alexandre V. Nikolaitchik
  • Patent number: 6344360
    Abstract: Compositions and methods for determining the presence or concentration of an analyte in a sample by exposing the sample to an indicator molecule comprising a fluorescent lanthanide metal chelate complex. The presence or concentration of the analyte in the sample is determined by observing and/or measuring the change in intensity of fluorescence emitted by the lanthanide metal chelate complex upon binding of the analyte to one or more recognition elements in the complex. The fluorescent indicator molecules can be used in various types of fluorescent sensing devices and are useful in various fields, including energy, medicine and agriculture.
    Type: Grant
    Filed: March 11, 1999
    Date of Patent: February 5, 2002
    Assignee: Sensors for Medicine and Science, Inc.
    Inventors: Arthur E. Colvin, George Y. Daniloff, Aristole G. Kalivretenos, David Parker, Edwin E. Ullman, Alexandre V. Nikolaitchik