Abstract: The present invention relates to an implantable device (1) comprising: —an ultrasonic unit (11) which includes an electric connection terminal, —a support plate (12) which includes a through-opening for the connection terminal to pass through, and —an attachment piece (13) which can cooperate with the connection terminal, the attachment piece (13) including a collar for pressing the support plate (12) against the ultrasonic unit (11) when the ultrasonic unit (11), the support plate (12) and the attachment piece (13) are joined.

Abstract: The present invention relates to a surgical kit for use in a craniectomy procedure, the surgical kit comprising: a medical device to be implanted in a cranial bone of a patient, the medical device (10) including several transducers for emitting ultrasound waves for treatment of brain tissue, a surgical accessory (20) intended to be positioned on the cranial bone of the patient, the surgical accessory (20) including a body whose outer perimeter defines the dimensions of an opening that is to be made in the cranial bone of the patient in order to receive the medical device, characterized in that the surgical accessory (20) comprises a plurality of holes (201) formed in the body, the position of each hole (201) on the body coinciding with the position of the axis of symmetry of a respective transducer, such that the accessory is able to be positioned optimally through the joint use of a neuronavigation system.

Abstract: The present invention relates to an implantable device (1) comprising: an ultrasonic unit (11) which includes an electric connection terminal, a support plate (12) which includes a through-opening for the connection terminal to pass through, and an attachment piece (13) which can cooperate with the connection terminal, the attachment piece (13) including a collar for pressing the support plate (12) against the ultrasonic unit (11) when the ultrasonic unit (11), the support plate (12) and the attachment piece (13) are joined.

Abstract: The present invention relates to an ultrasonic probe for heating, internally, an ultrasonically absorbent target medium, the probe comprising: at least one piezoelectric transducer (21) having a front face (212) intended to be positioned facing the target medium and a back face (211) opposite the front face (212), the transducer being able to emit at least one primary wave emanating from its front face and at least one secondary wave emanating from its back face, the probe being noteworthy in that it furthermore comprises: a reflector (24) facing the back face (211) of the transducer (21), the reflector (24) being suitable for reflecting the secondary wave emitted by the transducer (21); and a cooling-fluid layer (25) between the transducer (21) and the reflector (24).

Abstract: The present invention relates to a method for transiently disrupting a region of the blood-brain barrier (BBB) of a human using ultrasounds in the presence of an ultrasound contrast agent, and uses thereof. The method comprises the application of at least one ultrasound (US) beam with a pressure level higher than 1 MPa and a resonance frequency ranging from 0.5 to 1.5 MHz.

Abstract: The present invention relates to a surgical kit for use in a craniectomy procedure, the surgical kit comprising: a medical device to be implanted in a cranial bone of a patient, the medical device (10) including several transducers for emitting ultrasound waves for treatment of brain tissue, a surgical accessory (20) intended to be positioned on the cranial bone of the patient, the surgical accessory (20) including a body whose outer perimeter defines the dimensions of an opening that is to be made in the cranial bone of the patient in order to receive the medical device, characterized in that the surgical accessory (20) comprises a plurality of holes (201) formed in the body, the position of each hole (201) on the body coinciding with the position of the axis of symmetry of a respective transducer, such that the accessory is able to be positioned optimally through the joint use of a neuronavigation system.

Abstract: The present invention relates to an ultrasonic probe for heating, internally, an ultrasonically absorbent target medium, the probe comprising: at least one piezoelectric transducer (21) having a front face (212) intended to be positioned facing the target medium and a back face (211) opposite the front face (212), the transducer being able to emit at least one primary wave emanating from its front face and at least one secondary wave emanating from its back face, the probe being noteworthy in that it furthermore comprises: a reflector (24) facing the back face (211) of the transducer (21), the reflector (24) being suitable for reflecting the secondary wave emitted by the transducer (21); and a cooling-fluid layer (25) between the transducer (21) and the reflector (24).

Abstract: The present invention relates to a method for transiently disrupting a region of the blood-brain barrier (BBB) of a human using ultrasounds in the presence of an ultrasound contrast agent, and uses thereof. The method comprises the application of at least one ultrasound (US) beam with a pressure level higher than 1 MPa and a resonance frequency ranging from 0.5 to 1.5 MHz.