Abstract: A method for predicting risk of a future disease condition includes the steps of collecting and transporting bodily fluid to at least one colorimetric analyte sensing element, detecting the presence of bodily fluid, collecting optical data relating to the at least one colorimetric analyte sensing element with at least one spectrophotometer after a predetermined time period after detecting the presence of bodily fluid in contact with the colorimetric analyte sensing element, communicating the optical data to a computing system having at least one processor and data storage, analyzing the optical data to determine at least one analyte concentration in the bodily fluid, identifying a threshold analyte concentration of the at least one analyte in the bodily fluid that is an indicator of the risk of developing a future disease condition; and recording the at least one analyte concentration in the bodily fluid over time.

Abstract: A system and related methods include a durable component, an indicator component including an indicator zone comprising at least one colorimetric analyte sensing element, at least one moisture sensor, and a fluid collection reservoir. The durable component contains at least one spectrophotometer, a computing system, and means for electronic communication between the computing system and at least one external device. The indicator component includes at least one colorimetric analyte sensing element and a fluid transport layer in fluid communication with the indicator zone, and it is arranged and configured for attachment to the durable component. In addition, the moisture sensor is arranged and configured to communicate the presence of moisture to initiate a predetermined delay in measuring the concentration of at least one analyte. The fluid collection reservoir is releasable from at least one of the indicator components and the durable component at a predetermined breaking point for clinical analysis.

Abstract: A unit dose capsule for use with a sonic generator includes a deformable membrane adapted to releasably engage the distal end of the elongate horn, a nozzle including at least one delivery opening; a nozzle including at least one delivery opening; and a reservoir containing a liquid composition disposed therebetween. When the unit dose capsule is engaged to the distal end of the elongate horn, the nozzle is disposed in an outwardly facing orientation, and the reservoir is in liquid communication with the at least one nozzle. The unit dose capsule can be included in a kit with a handheld misting device comprising a housing having a dispensing window arranged and configured to contain a sonic generator and a power source.

Abstract: A system and related methods include a durable component, an indicator component including an indicator zone comprising at least one colorimetric analyte sensing element, at least one moisture sensor, and a fluid collection reservoir. The durable component contains at least one spectrophotometer, a computing system, and means for electronic communication between the computing system and at least one external device. The indicator component includes at least one colorimetric analyte sensing element and a fluid transport layer in fluid communication with the indicator zone, and it is arranged and configured for attachment to the durable component. In addition, the moisture sensor is arranged and configured to communicate the presence of moisture to initiate a predetermined delay in measuring the concentration of at least one analyte. The fluid collection reservoir is releasable from at least one of the indicator components and the durable component at a predetermined breaking point for clinical analysis.

Abstract: A unit dose capsule for use with a sonic generator includes a deformable membrane adapted to releasably engage the distal end of the elongate horn, a nozzle including at least one delivery opening; a nozzle including at least one delivery opening; and a reservoir containing a liquid composition disposed therebetween. When the unit dose capsule is engaged to the distal end of the elongate horn, the nozzle is disposed in an outwardly facing orientation, and the reservoir is in liquid communication with the at least one nozzle. The unit dose capsule can be included in a kit with a handheld misting device comprising a housing having a dispensing window arranged and configured to contain a sonic generator and a power source.

Abstract: A handheld misting device has a housing having a dispensing window is arranged and configured to contain a sonic generator, a power source coupled to the sonic generator, a plurality of reservoirs, each containing a liquid, and a plurality of nozzles, each nozzle arranged and configured for removable coupling to the sonic generator. Each nozzle is associated with and in liquid communication with a single reservoir. The sonic generator includes a converter and an elongate horn having a proximal end coupled to the converter and a distal end, and the nozzle is removably coupled to the distal end of the horn. Thus, the device delivers the liquid through a delivery opening formed in the nozzle, and activating the sonic generator energizes the liquid in the nozzle to generate an aerosol plume that is delivered through the dispensing window.

Abstract: An oral fluids sample collection method and apparatus includes a shield having a first face and a second face; an elastomeric nipple having an outer surface and defining a nipple interior extending from the first face of the shield; and a reservoir component extending from the second face of the shield comprising a reservoir having a reservoir interior. These elements are interconnected by a plurality of fluid conduit/valve combinations, including a first combination permitting flow from the nipple interior to an atmospheric vent port disposed on an exterior surface of the oral fluids collection device; a second combination permitting flow from the reservoir interior to the nipple interior; and a third combination permitting flow from a collection port disposed on the outer surface of the nipple to an exit port in the reservoir interior.

Abstract: A handheld misting device includes a sonic generator, a power source coupled to the sonic generator, at least one reservoir containing a first liquid, and a conduit from the at least one reservoir. The sonic generator includes a converter and an elongate horn comprising a first horn section coupled to the converter and a second horn section physically connected to and removable from the first horn section. Sonic energy delivered to the first horn section is conducted to the second horn section. The conduit transports liquid from the at least one reservoir to the second horn section to a delivery opening distal the first horn section.

Abstract: A method for predicting risk of a future disease condition includes the steps of collecting and transporting bodily fluid to at least one colorimetric analyte sensing element, detecting the presence of bodily fluid, collecting optical data relating to the at least one colorimetric analyte sensing element with at least one spectrophotometer after a predetermined time period after detecting the presence of bodily fluid in contact with the colorimetric analyte sensing element, communicating the optical data to a computing system having at least one processor and data storage, analyzing the optical data to determine at least one analyte concentration in the bodily fluid, identifying a threshold analyte concentration of the at least one analyte in the bodily fluid that is an indicator of the risk of developing a future disease condition; and recording the at least one analyte concentration in the bodily fluid over time.

Abstract: A system and kit for measuring analyte concentration in a bodily fluid include a durable component, at least one indicator component including an indicator zone, and at least one moisture sensor. The kit has multiple individually packaged indicator components. Methods of measuring analyte concentration in bodily fluids include the steps of collecting and transporting bodily fluid to at least one colorimetric analyte sensing element and detecting the presence of bodily fluid in contact with the at least one colorimetric analyte sensing element, collecting optical data relating to the at least one colorimetric analyte sensing element with at least one spectrophotometer after a predetermined time period after detecting the presence of bodily fluid, communicating the optical data to a computing system having at least one processor and data storage, and analyzing the optical data to determine at least one analyte concentration in the bodily fluid.

Abstract: A disposable indicator component for use in a system for measuring analyte concentration in a bodily fluid includes an indicator zone comprising at least one colorimetric analyte sensing element, and a coupler for coupling the indicator component to a component having at least one spectrophotometer contained within a housing.

Abstract: A device for treating the brain includes a light source configured to emit near infrared light. The device also includes a collimator configured to receive the near infrared light emitted by the light emitter. The collimator is further configured to collimate the near infrared light. The device also includes an optic configured to focus collimated light. A reflector of the device is configured to change a direction of the collimated light. The reflector is at a distal end of the device, and the distal end is configured to fit between an upper portion of an eyelid of a patient and an orbital socket of the patient.

Abstract: A dual modality system includes a chassis having a receptacle and means to couple the chassis to a desired treatment area of a user's body; a durable energy subsystem coupled to the chassis, arranged and configured to deliver energy to the desired treatment area of a user's body; and a replaceable thermal subsystem arranged and configured for removable placement in the receptacle of the chassis, arranged and configured to deliver thermal energy.

Abstract: A dual modality system includes a flexible chassis including a durable energy subsystem and a replaceable thermal subsystem. The durable energy subsystem has a plurality of energy emitters disposed in an emission region of the chassis having a length and a width, wherein the emission region length and emission region width are both substantially greater than an emission region depth. The replaceable thermal subsystem has a thermal source affixed to flexible web having an adhesive surface and at least one structure arranged and configured to couple the thermal subsystem to a chassis comprising a durable energy subsystem in a configuration wherein the thermal source is substantially superposed over the emission region of the chassis.

Abstract: An economical dual modality system is useful in a system for independent delivery of two distinct energy modalities to a mammalian body and includes a thermal subsystem. The thermal subsystem includes a thermal source affixed to flexible web having an adhesive surface and at least one structure arranged and configured to couple the thermal subsystem to a chassis comprising a durable energy subsystem.

Abstract: A device for treating the brain includes a light source configured to emit near infrared light. The device also includes a collimator configured to receive the near infrared light emitted by the light emitter. The collimator is further configured to collimate the near infrared light. The device also includes an optic configured to focus collimated light. A reflector of the device is configured to change a direction of the collimated light. The reflector is at a distal end of the device, and the distal end is configured to fit between an upper portion of an eyelid of a patient and an orbital socket of the patient.

Abstract: A method for at-home skin condition analyses includes coupling an adapter to a port of a wearable lamp platform. placing the wearable lamp platform on a portion of a user's body, coupling a data acquisition device to the adapter and activating the data acquisition device to acquire data pertaining to the user's body through the optical lens, analyzing the data pertaining to the user's body, determining a light treatment regimen for the user's body, and applying light treatment to the user's body according to the determined light treatment regimen. The port has disposed therein an optical lens and having a plurality of image image-acquisition lamps disposed thereabout. The image-acquisition lamps are energized by a power source electrically coupled to the wearable lamp platform, and the wearable lamp platform comprises a plurality of treatment lamps arranged and configured to irradiate a portion of a wearer's body.

Abstract: A kit comprising a wearable lamp platform a frame for holding the wearable lamp platform in a fixed orientation spaced from the user's body, an adapter arranged and configured to couple a data acquisition device to the optical lens of the at least one port; and a power source controller electrically coupled to the wearable lamp platform provides a simple and elegant solution to providing economic, at-home skin condition analyses. The wearable lamp platform includes a plurality of treatment lamps arranged and configured to irradiate a portion of a wearer's body, and at least one port extending through the lamp platform from the outer surface to the inner surface. The at least one port has disposed therein an optical lens and a plurality of image-acquisition lamps disposed thereabout.

Abstract: A system to generate a vapor from a liquid includes an electric heater and an elongate wick. The electric heater defines an interior void having an inner surface and a plurality of apertures, and it is formed of an electrically resistive material contained within a heat diffusing material. The elongate wick is formed of a durable elongate structure having a plurality of liquid-conducting features on the outer surface. At least a portion of the liquid-conducting features of the elongate wick proximate the first end engage at least a portion of the one inner surface of the electric heater and are capable of conducting a the liquid from a source proximate the second end of the wick along the outer surface of the elongate wick to the electric heater.

Abstract: A system for delivering energy to an isolated part of a mammalian body includes an electrically powered patch and a self-supporting adhesive film. The patch has a major surface and comprises a matrix of at least one flexible, biocompatible material which is capable of conforming to the isolated body part. The self-supporting adhesive film has a first non-tacky surface arranged and configured for releasable attachment to the patch and a second tacky surface, opposite the first surface, for adhesive attachment to the isolated body part. The releasable attachment between the self-supporting adhesive film and the electrically powered patch has a lower strength than the adhesive attachment between the film and the isolated body part. Thus, during use the electrically powered patch is removable from the self-supporting adhesive film while leaving the self-supporting adhesive film adhered to the isolated body part.