Patents by Inventor Alexandru TREFILOV

Alexandru TREFILOV has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microparticles for cell disruption and/or biomolecule recovery
    Patent number: 10661264
    Abstract: The present invention provides novel methods of cell disruption and release of biomolecules from a cell. The invention comprises the use of positively and/or negatively charged microparticles comprising ground resin. It is particularly useful for purification of biomolecules from cell culture.
    Type: Grant
    Filed: August 14, 2018
    Date of Patent: May 26, 2020
    Assignees: BOEHRINGER INGELHEIM RCV GMBH & CO KG, SANDOZ AG
    Inventors: Rainer Hahn, Alois Jungbauer, Alexandru Trefilov
  • Adsorbent composition and use thereof
    Patent number: 10537887
    Abstract: The present invention provides a novel adsorbent composition for recovering biomolecules from a fluid. The composition comprises positively and negatively charged microparticles in the form of ground particles. The adsorbent is particularly useful for purification of biomolecules from the cell culture.
    Type: Grant
    Filed: August 25, 2014
    Date of Patent: January 21, 2020
    Assignees: BOEHRINGER INGELHEIM RCV & GMBH CO KG, SANDOZ AG
    Inventors: Rainer Hahn, Alois Jungbauer, Alexandru Trefilov, Moritz Imendoerffer
  • MICROPARTICLES FOR CELL DISRUPTION AND/OR BIOMOLECULE RECOVERY
    Publication number: 20190046969
    Abstract: The present invention provides novel methods of cell disruption and release of biomolecules from a cell. The invention comprises the use of positively and/or negatively charged microparticles comprising ground resin. It is particularly useful for purification of biomolecules from cell culture.
    Type: Application
    Filed: August 14, 2018
    Publication date: February 14, 2019
    Inventors: Rainer Hahn, Alois Jungbauer, Alexandru Trefilov
  • Microparticles for cell disruption and/or biomolecule recovery
    Patent number: 10076749
    Abstract: The present invention provides novel methods of cell disruption and release of biomolecules from a cell. The invention comprises the use of positively and/or negatively charged microparticles comprising ground resin. It is particularly useful for purification of biomolecules from cell culture.
    Type: Grant
    Filed: August 25, 2014
    Date of Patent: September 18, 2018
    Assignees: BOEHRINGER INGELHEIM RCV GMBH & CO KG, SANDOZ AG
    Inventors: Rainer Hahn, Alois Jungbauer, Alexandru Trefilov
  • MICROPARTICLES FOR CELL DISRUPTION AND/OR BIOMOLECULE RECOVERY
    Publication number: 20160200760
    Abstract: The present invention provides novel methods of cell disruption and release of biomolecules from a cell. The invention comprises the use of positively and/or negatively charged microparticles comprising ground resin. It is particularly useful for purification of biomolecules from cell culture.
    Type: Application
    Filed: August 25, 2014
    Publication date: July 14, 2016
    Inventors: Rainer HAHN, Alois JUNGBAUER, Alexandru TREFILOV
  • NOVEL ADSORBENT COMPOSITION AND USE THEREOF
    Publication number: 20160193598
    Abstract: The present invention provides a novel adsorbent composition for recovering biomolecules from a fluid. The composition comprises positively and negatively charged microparticles in the form of ground particles. The adsorbent is particularly useful for purification of biomolecules from the cell culture.
    Type: Application
    Filed: August 25, 2013
    Publication date: July 7, 2016
    Applicant: Boehringer Ingelhelim RCV GMBH & Co KG
    Inventors: Rainer HAHN, Alois JUNGBAUER, Alexandru TREFILOV, Moritz IMENDOERFFER