Patents by Inventor Alexei Savinov

Alexei Savinov has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS RELATED TO MMP26 STATUS AS A DIAGNOSTIC AND PROGNOSTIC TOOL IN CANCER MANAGEMENT
    Publication number: 20070218512
    Abstract: Disclosed herein are compositions and methods involving identifying MMP-26 in a subject with cancer.
    Type: Application
    Filed: February 28, 2007
    Publication date: September 20, 2007
    Inventors: Alex Strongin, Stan Krajewski, Maryla Krajewski, Alexei Savinov
  • INHIBITORS OF MEMBRANE TYPE-1 MATRIX METALLOPROTEINASE FOR THE TREATMENT OF INSULIN-DEPENDENT DIABETES MELLITUS
    Publication number: 20070203244
    Abstract: Provided herein are compositions and methods for inhibiting the transmigration of T cells through pancreatic capillary endothelium and treating insulin-dependent diabetes mellitus (IDDM; type I diabetes) using inhibitors of MT1-MMP.
    Type: Application
    Filed: February 7, 2007
    Publication date: August 30, 2007
    Inventors: Alex Strongin, Alexei Savinov, Dimitri Rozanov
  • Methods of modulating homing of T cell by interruption of chemokine/chemokine receptor signaling
    Publication number: 20050008639
    Abstract: In certain embodiments, the invention relates to methods of modulating homing of T cells to the pancreas. Such methods comprise contacting the cells with an agonist or an antagonist of the chemokine CCL21, or with an agonist or an antagonist of a chemokine receptor of the T cells. In other embodiments, the invention relates to methods of treating an individual suffering from insulin-dependent diabetes. Such methods comprise administering to the individual an antagonist of the chemokine CCL21 or a chemokine receptor of the T cells. In yet other embodiments, the invention relates to methods of preventing or reducing the onset of insulin-dependent diabetes in an individual. Such methods comprise administering to the individual an antagonist of the chemokine CCL21 or a chemokine receptor of the T cells.
    Type: Application
    Filed: February 12, 2004
    Publication date: January 13, 2005
    Inventors: Alexander Chervonsky, Alexei Savinov