Patents by Inventor Alexis A. Cordi

Alexis A. Cordi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8653073
    Abstract: Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
    Type: Grant
    Filed: February 21, 2013
    Date of Patent: February 18, 2014
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Claude Ortuno, Alexis Cordi, Jean-Michel Lacoste, Imre Fejes, Michael Burnbridge, John Hickman, Alain Pierre
  • Patent number: 8569285
    Abstract: Compounds of formula (I): wherein R1 represents a hydrogen atom or a heterocyclic, cyano, alkoxycarbonyl, alkylsulphonylaminoalkyl or N-hydroxycarboximidamide group. Medicinal products containing the same which are useful as modulators of the AMPA receptor.
    Type: Grant
    Filed: September 15, 2011
    Date of Patent: October 29, 2013
    Assignee: Les Laboratoires Servier
    Inventors: Alexis Cordi, Patrice Desos, Pierre Lestage, Laurence Danober
  • Patent number: 8541412
    Abstract: Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
    Type: Grant
    Filed: November 2, 2011
    Date of Patent: September 24, 2013
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Claude Ortuno, Alexis Cordi, Imre Fejes, Vincent Lacoste, Pauline Lacoste
  • Patent number: 8288433
    Abstract: Compounds of formula (I): wherein: R1 represents a hydrogen atom or a —COOR group, R2 represents a group G or a linear or branched (C1-C6)alkyl group substituted by a group G, wherein G represents a —(CH2)n-A-(CH2)m—B—(CR4R5)p—(CH2)o—R6 group as defined in the description, R3 represents a hydrogen atom, an alkyl group or an NO2 group. Medicinal products containing the same which are useful in treating hypertension and cardiovascular pathologies.
    Type: Grant
    Filed: December 10, 2008
    Date of Patent: October 16, 2012
    Assignee: Les Laboratoires Servier
    Inventors: Alexis Cordi, Laure Haberkorn, Tony Verbeuren, Christine Courchay, Serge Simonet
  • Patent number: 8236790
    Abstract: Compounds of formula (I): wherein: R1 and R2, which may be the same or different, each represent a hydrogen or halogen atom or an alkyl, alkoxy, alkylthio, acyl, alkoxycarbonyl, carboxy, hydroxy, hydroxyalkyl, cyano, nitro, amino, substituted or unsubstituted aminocarbonyl, aminosulphonyl, alkylsulphonylaminoalkyl, N-hydroxy-carboximidamide or benzyloxy group, R3 represents a hydrogen atom or an alkyl, cycloalkyl or cycloalkylalkyl group, R4 represents a hydrogen atom or a substituted or unsubstituted alkyl group Medicinal products containing the same which are useful in treating or preventing conditions treatable by an AMPA receptor modulator and/or an NMDA receptor antagonist.
    Type: Grant
    Filed: March 19, 2010
    Date of Patent: August 7, 2012
    Assignee: Les Laboratories Servier
    Inventors: Alexis Cordi, Patrice Desos, Pierre Lestage, Laurence Danober
  • Patent number: 8173644
    Abstract: This invention relates to the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for higher order behaviors. These brain networks are involved in cognitive abilities related to memory impairment, such as is observed in a variety of dementias, an in imbalances in neuronal activity between different brain regions, as is suggested in disorders such as Parkinson's disease, schizophrenia and affective disorders. In a particular aspect, the present invention relates to a compound useful for treatment of such conditions, and methods of using this compound for such treatment.
    Type: Grant
    Filed: December 28, 2007
    Date of Patent: May 8, 2012
    Assignee: Les Laboratoires Servier
    Inventors: Alexis Cordi, Gary Rogers, Rudolf Mueller
  • Publication number: 20120071462
    Abstract: Compounds of formula (I): wherein R1 represents a hydrogen atom or a heterocyclic, cyano, alkoxycarbonyl, alkylsulphonylaminoalkyl or N-hydroxycarboximidamide group. Medicinal products containing the same which are useful as modulators of the AMPA receptor.
    Type: Application
    Filed: September 15, 2011
    Publication date: March 22, 2012
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Alexis Cordi, Patrice Desos, Pierre Lestage, Laurence Danober
  • Patent number: 8133889
    Abstract: Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
    Type: Grant
    Filed: August 4, 2010
    Date of Patent: March 13, 2012
    Assignee: Les Laboratoires Servier
    Inventors: Jean-Claude Ortuno, Alexis Cordi, Jean-Michel Lacoste, Vincent Lacoste, legal representative, Pauline Lacoste, legal representative, Imre Fejes, Michael Burbridge, John Hickman, Alain Pierre
  • Publication number: 20120046287
    Abstract: Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
    Type: Application
    Filed: November 2, 2011
    Publication date: February 23, 2012
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Jean-Claude Ortuno, Alexis Cordi, Jean-Michel Lacoste, Vincent Lacoste, Pauline Lacoste, Imre Fejes
  • Publication number: 20110034460
    Abstract: Compounds of formula (I): wherein: m and n represent 1 or 2, A represents a pyrrolyl group, X represents a C(O), S(O) or SO2 group, R1 and R2 represent an alkyl group or, together with the nitrogen atom carrying them, form a heterocyclic group, R3 and R4, together with the atoms carrying them, form a heterocyclic group, R5 represents a hydrogen atom or an alkyl group, R6 represents a hydrogen atom or a halogen atom. Medicinal products containing the same which are useful in treating cancer.
    Type: Application
    Filed: August 4, 2010
    Publication date: February 10, 2011
    Applicant: Les Laboratoires Servier
    Inventors: Jean-Claude Ortuno, Alexis Cordi, Jean-Michel Lacoste, Vincent Lacoste, Pauline Lacoste, Imre Fejes, Michael Burbridge, John Hickman, Alain Pierre
  • Publication number: 20100286225
    Abstract: Compounds of formula (I): wherein: R1 represents a hydrogen atom or a —COOR group, R2 represents a group G or a linear or branched (C1-C6)alkyl group substituted by a group G, wherein G represents a —(CH2)n-A-(CH2)m—B—(CR4R5)p—(CH2)o-R6 group as defined in the description, R3 represents a hydrogen atom, an alkyl group or an NO2 group.
    Type: Application
    Filed: December 10, 2008
    Publication date: November 11, 2010
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Alexis Cordi, Laure Haberkorn, Tony Verbeuren, Christine Courchay, Serge Simonet
  • Publication number: 20100240635
    Abstract: Compounds of formula (I): wherein: R1 and R2, which may be the same or different, each represent a hydrogen or halogen atom or an alkyl, alkoxy, alkylthio, acyl, alkoxycarbonyl, carboxy, hydroxy, hydroxyalkyl, cyano, nitro, amino, substituted or unsubstituted aminocarbonyl, aminosulphonyl, alkylsulphonylaminoalkyl, N-hydroxy-carboximidamide or benzyloxy group, R3 represents a hydrogen atom or an alkyl, cycloalkyl or cycloalkylalkyl group, R4 represents a hydrogen atom or a substituted or unsubstituted alkyl group Medicinal products containing the same which are useful in treating or preventing conditions treatable by an AMPA receptor modulator and/or an NMDA receptor antagonist.
    Type: Application
    Filed: March 19, 2010
    Publication date: September 23, 2010
    Applicant: LES LABORATOIRES SERVIER
    Inventors: Alexis Cordi, Patrice Desos, Pierre Lestage, Laurence Danober
  • Publication number: 20100137295
    Abstract: This invention relates to the prevention and treatment of cerebral insufficiency, including enhancement of receptor functioning in synapses in brain networks responsible for higher order behaviors. These brain networks are involved in cognitive abilities related to memory impairment, such as is observed in a variety of dementias, and in imbalances in neuronal activity between different brain regions, as is suggested in disorders such as Parkinson's disease, schizophrenia and affective disorders. In a particular aspect, the present invention relates to a compound useful for treatment of such conditions, and methods of using this compound for such treatment.
    Type: Application
    Filed: December 28, 2007
    Publication date: June 3, 2010
    Inventor: Alexis Cordi
  • Patent number: 7494995
    Abstract: A compound selected from those of formula (I): wherein: R1 represents an NR3SO2R4 group wherein: R3 represents a hydrogen atom or an alkyl group, R4 represents an alkyl group, aryl group or NR5R6 group, R2 represents an alkyl, cycloalkyl or cycloalkylalkyl group, and medicinal products containing the same which are useful in treating conditions treatable by antagonists of type H3 central histamine receptors.
    Type: Grant
    Filed: May 11, 2006
    Date of Patent: February 24, 2009
    Assignee: Les Laboratoires Servier
    Inventors: Patrice Desos, Alexis Cordi, Pierre Lestage
  • Patent number: 7494994
    Abstract: A compound selected from those of formula (I): wherein: X represents a C(O) or SO2 group, R1 represents an aryl group or a group NR3R4 wherein R3 and R4 are as defined in the description, R2 represents an alkyl, (C3-C8)cycloalkyl or (C3-C8)cycloalkyl-(C1-C6)alkyl group, its isomers, and addition salts thereof, and medicinal products containing the same which are useful in treating conditions treatable by antagonists of type H3 central histamine receptors.
    Type: Grant
    Filed: May 11, 2006
    Date of Patent: February 24, 2009
    Assignee: Les Laboratoires Servier
    Inventors: Patrice Desos, Alexis Cordi, Pierre Lestage
  • Publication number: 20070270415
    Abstract: The invention relates to compounds of formula (I): wherein: R1 represents alkyl substituted by one or more halogen atoms, R2 represents hydrogen, halogen or hydroxy, R3 represents unsubstituted or substituted aryl, their isomers, and also addition salts thereof. and medicinal products containing the same which are useful in treating or preventing disorders associated with AMPA flux.
    Type: Application
    Filed: July 27, 2007
    Publication date: November 22, 2007
    Applicant: LESLABORATOIRES SERVIER
    Inventors: Patrice Desos, Alexis Cordi, Pierre Lestage
  • Patent number: 7268130
    Abstract: The invention relates to compounds of formula (I): wherein: R1 represents alkyl substituted by one or more halogen atoms, R2 represents hydrogen, halogen or hydroxy, R3 represents unsubstituted or substituted aryl, their isomers, and also addition salts thereof. and medicinal products containing the same which are useful in treating or preventing disorders associated with AMPA flux.
    Type: Grant
    Filed: November 2, 2005
    Date of Patent: September 11, 2007
    Assignee: Les Laboratoires Servier
    Inventors: Patrice Desos, Alexis Cordi, Pierre Lestage
  • Patent number: 7262190
    Abstract: The invention relates to compounds of formula (I): wherein: R1 represents hydrogen, alkyl or cycloalkyl, R2 represents hydrogen, halogen or hydroxy, A represents CR3R4 or NR3 wherein R3 and R4 are as defined in the description, Y represents an alkylene chain as described in the description, X represents NR5R6, S(O)nR7, OR8, C(O)R9, amidino or a heterocycle, their isomers, and addition salts thereof; and medicinal products containing the same which are useful in the prevention or treatment of diseases associated with AMPA flux.
    Type: Grant
    Filed: December 8, 2005
    Date of Patent: August 28, 2007
    Assignee: Les Laboratoires Servier
    Inventors: Patrice Desos, Alexis Cordi, Pierre Lestage, Laurence Danober
  • Patent number: 7262191
    Abstract: The invention relates to compounds of formula (I): wherein: X represents oxygen or sulphur, R1 represents linear or branched (C1-C6)alkyl substituted by one or more halogen atoms, R2 represents hydrogen, halogen or hydroxy, R3 represents a group R4 or —Y—R5 wherein R4, Y and R5 are as defined in the description, and medicinal products containing the same which are useful in treating or preventing disorders associated with AMPA flux.
    Type: Grant
    Filed: November 3, 2005
    Date of Patent: August 28, 2007
    Assignee: Les Laboratories Servier
    Inventors: Patrice Desos, Alexis Cordi, Pierre Lestage
  • Publication number: 20060258671
    Abstract: A compound selected from those of formula (I): wherein: R1 represents an NR3SO2R4 group wherein: R3 represents a hydrogen atom or an alkyl group, R4 represents an alkyl group, aryl group or NR5R6 group, R2 represents an alkyl, cycloalkyl or cycloalkylalkyl group, and medicinal products containing the same which are useful in treating conditions treatable by antagonists of type H3 central histamine receptors.
    Type: Application
    Filed: May 11, 2006
    Publication date: November 16, 2006
    Inventors: Patrice Desos, Alexis Cordi, Pierre Lestage