Patents by Inventor Alexis Borisy

Alexis Borisy has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Combinations of drugs for the treatment of neoplasms
    Publication number: 20040116407
    Abstract: The invention features a method for treating a patient having a cancer or other neoplasm by administering to the patient two compounds simultaneously or within 14 days of each other in amounts sufficient to treat the patient.
    Type: Application
    Filed: July 11, 2003
    Publication date: June 17, 2004
    Inventors: Alexis Borisy, Curtis Keith, Michael A. Foley, Brent R. Stockwell, Debra A. Gaw, M. James Nichols, Margaret S. Lee
  • Combinations for the treatment of inflammatory disorders
    Publication number: 20040116395
    Abstract: The invention features a pharmaceutical composition that includes amoxapine and a corticosteroid.
    Type: Application
    Filed: September 29, 2003
    Publication date: June 17, 2004
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Combinations for the treatment of inflammatory disorders
    Publication number: 20040110734
    Abstract: The invention features methods and compositions for the treatment of immunonflammatory disorders.
    Type: Application
    Filed: November 19, 2003
    Publication date: June 10, 2004
    Inventors: Robyn Sackeyflo, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders
    Publication number: 20040063769
    Abstract: The invention features a method for treating a patient having a cancer or other neoplasm, by administering to the patient (i) a benzimidazole or a metabolite or analog thereof; and (ii) pentamidine or a metabolite or analog thereof simultaneously or within 14 days of each other in amounts sufficient to inhibit the growth of the neoplasm.
    Type: Application
    Filed: October 2, 2003
    Publication date: April 1, 2004
    Inventors: Alexis Borisy, Curtis Keith, Michael A. Foley, Brent R. Stockwell
  • Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders
    Patent number: 6693125
    Abstract: The invention features a method for treating a patient having a cancer or other neoplasm, by administering to the patient (i) a benzimidazole or a metabolite or analog thereof; and (ii) pentamidine or a metabolite or analog thereof simultaneously or within 14 days of each other in amounts sufficient to inhibit the growth of the neoplasm.
    Type: Grant
    Filed: January 24, 2001
    Date of Patent: February 17, 2004
    Assignee: CombinatoRx Incorporated
    Inventors: Alexis Borisy, Curtis Keith, Michael A. Foley, Brent R. Stockwell
  • Combinations of drugs for the treatment of neoplastic disorders
    Publication number: 20030166642
    Abstract: The invention features a method for treating a patient having a cancer or other neoplasm by administering to the patient two compounds simultaneously or within 14 days of each other in amounts sufficient to treat the patient.
    Type: Application
    Filed: January 21, 2003
    Publication date: September 4, 2003
    Inventors: Alexis Borisy, Curtis Keith, Michael A. Foley, Brent R. Stockwell
  • Combinations for the treatment of immunoinflammatory disorders
    Publication number: 20030119786
    Abstract: The invention features a method for treating a patient having an immunoinflammatory disorder, by administering to the patient (i) a tetra-substituted pyrimidopyrimidine, and (ii) a corticosteroid simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit immunoinflammation.
    Type: Application
    Filed: October 4, 2002
    Publication date: June 26, 2003
    Inventors: Curtis Keith, Alexis Borisy, Grant Zimmerman, Edward Roydon Jost-Price, Palaniyandi Manivasakam, Nicole Hurst, Michael A. Foley
  • Combinations of chlorpromazine and pentamidine for the treatment of neoplastic disorders
    Patent number: 6569853
    Abstract: The invention features a method for treating a patient having a cancer or other neoplasm, by administering to the patient (i) chlorpromazine or a metabolite or analog thereof; and (ii) pentamidine or a metabolite or analog thereof simultaneously or within 14 days of each other in amounts sufficient to inhibit the growth of the neoplasm.
    Type: Grant
    Filed: November 6, 2000
    Date of Patent: May 27, 2003
    Assignee: CombinatoRx, Incorporated
    Inventors: Alexis Borisy, Curtis Keith, Michael A. Foley, Brent R. Stockwell
  • Screening system for identifying drug-drug interactions and methods of use thereof
    Publication number: 20030096309
    Abstract: The invention features a method of screening for drug-drug interactions using combinational arrays. The method includes the steps of: (a) providing (i) a test drug; (ii) a drug library; and (iii) an assay, (b) contacting the test drug and at least some of the library drugs from the drug library in the assay under conditions that ensure that each test drug/library drug contacting is segregated from the others, (c) recording the result of the contacting of the test drug and the library drug in the assay, and (d) identifying combinations of drugs that produce a result in the assay that is different from the results produced by either drug of the combination by itself. According to the method, each of the identified combinations indicates an interaction between the test drug and the library drug.
    Type: Application
    Filed: August 20, 2002
    Publication date: May 22, 2003
    Inventors: Alexis Borisy, Daniel Grau, Brent R. Stockwell, Curtis Keith
  • Combinations for the treatment of inflammatory disorders
    Publication number: 20030078246
    Abstract: The invention features a method for treating a patient having an inflammatory disorder, by administering to the patient (i) a tricyclic antidepressant (e.g., amoxapine); and (ii) a corticosteroid (e.g., prednisolone) simultaneously or within 14 days of each other in amounts sufficient to reduce or inhibit inflammation.
    Type: Application
    Filed: July 9, 2002
    Publication date: April 24, 2003
    Inventors: Robyn Sackeyfio, Jason Fong, Nicole Hurst, Palaniyandi Manivasakam, Edward Roydon Jost-Price, Grant Zimmermann, Curtis Keith, Alexis Borisy
  • Combinations of drugs (e.g., a benzimidazole and pentamidine) for the treatment of neoplastic disorders
    Publication number: 20020165261
    Abstract: The invention features a method for treating a patient having a cancer or other neoplasm, by administering to the patient (i) a benzimidazole or a metabolite or analog thereof; and (ii) pentamidine or a metabolite or analog thereof simultaneously or within 14 days of each other in amounts sufficient to inhibit the growth of the neoplasm.
    Type: Application
    Filed: January 24, 2001
    Publication date: November 7, 2002
    Inventors: Alexis Borisy, Curtis Keith, Michael A. Foley, Brent R. Stockwell
  • Methods for identifying combinations of entities as therapeutics
    Publication number: 20020019011
    Abstract: The invention features a method of screening two-entity or higher order combinations for biological activity using combinational arrays. The method includes the steps of: (a) providing the entities, (b) creating an array of combinations of entities, (c) providing a test element that includes one or more distinct biological moieties, (d) contacting the array of combinations of entities with the test element under conditions that ensure that each entity/test element contacting is segregated from the others, (e) detecting or measuring a property of the test element, and (f) identifying combinations of entities that cause an effect on the property of the test element that is different from the effect of an entity of the combination by itself.
    Type: Application
    Filed: March 22, 2001
    Publication date: February 14, 2002
    Inventors: Brent R. Stockwell, Alexis Borisy, Michael A. Foley
  • Methods for identifying combinations of entities as therapeutics
    Publication number: 20020019010
    Abstract: The invention features a method of screening two-entity or higher order combinations for biological activity using combinational arrays. The method includes the steps of: (a) providing the entities, (b) creating an array of combinations of entities, (c) providing a test element that includes one or more distinct biological moieties, (d) contacting the array of combinations of entities with the test element under conditions that ensure that each entity/test element contacting is segregated from the others, (e) detecting or measuring a property of the test element, and (f) identifying combinations of entities that cause an effect on the property of the test element that is different from the effect of an entity of the combination by itself.
    Type: Application
    Filed: March 22, 2001
    Publication date: February 14, 2002
    Inventors: Brent R. Stockwell, Alexis Borisy, Michael A. Foley