Patents by Inventor Alexis KALERGIS PARRA

Alexis KALERGIS PARRA has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240042012
    Abstract: The invention relates to an immunogenic formulation containing one or more modified recombinant strains of Bacillus Calmette-Guerin (BCG), in a concentration between 104?109 bacteria, where each BCG strain expresses at least one protein or immunogenic fragment of SARS-CoV-2, in a pharmaceutically acceptable saline buffer, where this formulation serves to prepare vaccines to prevent, treat or attenuate SARS-CoV-2 infections.
    Type: Application
    Filed: December 23, 2021
    Publication date: February 8, 2024
    Inventors: Alexis KALERGIS PARRA, Susan BUENO RAMÍREZ, Pablo GONZALEZ MUÑOZ, Angello RETAMAL DIAZ, Jorge SOTO RAMIREZ
  • Publication number: 20230390378
    Abstract: The invention relates to an immunogenic formulation containing the bacillus Calmette-Guerin (BCG) strain in a concentration between 104-109 bacteria, expressing at least one protein or immunogenic fragment of Andesvirus (ANDV), in a pharmaceutically acceptable saline buffer solution, which serves to prepare a vaccine useful for preventing, treating or attenuating ANDV infections. ANDV belongs to the Hantavirus family and is a highly virulent human pathogen, which annually affects dozens of people in Chile generating in some infected a Hantavirus Cardiopulmonary Syndrome (HCPS).
    Type: Application
    Filed: November 10, 2021
    Publication date: December 7, 2023
    Inventors: Alexis KALERGIS PARRA, Susan BUENO RAMÍREZ, Pablo GONZALEZ MUÑOZ
  • Publication number: 20210347862
    Abstract: The invention relates to a monoclonal antibody or fragment thereof, which recognizes the N (nucleocapsid) protein of the human respiratory syncytial virus (RSV), useful for the development of diagnostic methods for RSV infection and for the production of pharmaceutical compositions intended for the treatment, protection and/or prophylaxis of RSV infection.
    Type: Application
    Filed: September 3, 2018
    Publication date: November 11, 2021
    Inventors: Alexis KALERGIS PARRA, Susan BUENO RAMÍREZ
  • Publication number: 20210347856
    Abstract: The present invention refers to a new monoclonal antibody or fragment thereof, called 14F5F6, which specifically recognizes herpes simplex virus (HSV), in its two types, herpes simplex virus type 1 and herpes simplex virus type 2 (HSV-1 and HSV-2). Preferably, the antibody of the invention is useful for the development of methods for the diagnosis of herpes simplex virus infection, as well as for the production of pharmaceutical compositions intended for the treatment, protection and/or prophylaxis of infection specifically caused by HSV-1 and HSV-2.
    Type: Application
    Filed: August 28, 2018
    Publication date: November 11, 2021
    Inventors: Alexis KALERGIS PARRA, Susan BUENO RAMÍREZ, Pablo GONZALEZ MUÑOZ
  • Publication number: 20210347857
    Abstract: The present invention refers to a new monoclonal antibody or fragment thereof, called 11B2C7, which specifically recognizes herpes simplex virus (HSV), in its two types, herpes simplex virus type 1 and herpes simplex virus type 2 (HSV-1 and HSV-2). Preferably, the antibody of the invention is useful for the development of methods for the diagnosis of herpes simplex virus infection, as well as for the production of pharmaceutical compositions intended for the treatment, protection and/or prophylaxis of infection specifically caused by HSV-1 and HSV-2.
    Type: Application
    Filed: August 28, 2018
    Publication date: November 11, 2021
    Inventors: Alexis KALERGIS PARRA, Susan BUENO RAMÍREZ, Pablo GONZALEZ MUÑOZ