Abstract: Cosmetic treatment method for adding fibers to natural eyelashes, comprising: a) applying an adhesive composition (A) to at least part of the eyelashes, b) bringing fibers (12) borne by an applicator (10) into contact with said adhesive composition (A) present on said eyelashes, c) moving the applicator (10) away from the eyelashes, so as to release fibers (12) which adhere to said eyelashes.

Abstract: A cosmetic applicator (3) for applying a composition (P) to human keratinous fibers, notably eyelashes or eyebrows, is provided. The cosmetic applicator (3) comprises: —A stem (5) having at least a rectilinear portion extending along a rectilinear axis (Y), —a brush (10) at one end of the stem (5), the brush comprising: —a curved core (43) having a distal end (46) and defining a convex side and an opposite concave side, the distal end of the core being offset from the rectilinear axis (Y) of the stem on the convex side of the core, —application members (41) supported by the core (43).

Abstract: This invention relates to a cosmetic product applicator (14) including: —a gripping member (16) extending along a longitudinal axis (A), —a rod carrier (18) arranged in the gripping member (16), —a rod (20) secured to the rod carrier (18) and —a cosmetic product application member (22) carried by the rod (20), the rod carrier being (18) mounted mobile in rotation about the longitudinal axis (A) with respect to the gripping member (16), The rod carrier (18) has a first and a second circumferential linear contact region (86, 90) with the gripping member (16) about the longitudinal axis (A) and a second circumferential linear contact region (86, 90) with the gripping member (16) about the longitudinal axis (A), the rod carrier (18) being arranged totally apart from the gripping member (16) in an intermediate region (92) between the first linear contact region (86) and the second linear contact region (90).

Abstract: Packaging and application device, including: a container containing a product to be applied, a screen through which the product contained in the container exits, the screen having dispensing orifices with different sections, with at least three orifices of which the section varies in a strictly decreasing manner with distance from the centre of the screen.

Abstract: The invention relates to an applicator for applying a cosmetic product, such as a mascara, including a gripping member, a stem extending along a longitudinal axis and having, along said longitudinal axis, a first end secured to the gripping member and a second, opposite end, an applicator member for applying the cosmetic product, which is secured to the second end of the stem and includes a brush comprising a core and bristles that are held by the core in a portion of the core bearing the bristles, the bristles having free ends that define an envelope surface, and a comb having a plurality of application elements borne by a holder, wherein the holder of the comb is made in one piece with the stem.

Abstract: The invention relates to a process for applying a coating composition on keratin fibers, comprising the following steps: a) application of a base composition on the keratin fibers; then b) application of a coating composition of the base composition on the keratin fibers, the application of the coating composition comprising the driving in rotation of an application member with respect to a gripping member, by displacing the application member on said keratin fibers, the application member being impregnated with said coating composition of the base composition.

Abstract: Use of an applicator in free rotation for the makeup removal of mascara The invention also has for object a cosmetic application requisite comprising: —an application member able to be driven in rotation by the keratin fibers with respect to a gripping member; and —makeup removal composition for keratin fibers comprising an aqueous phase and at least one surfactant. It also has for object a method for applying this requisite.

Abstract: The present invention relates to a device (1) for packaging and applying at least one cosmetic product, comprising: —a container (2) delimiting at least two compartments (11, 12), —a closure cap (3) for closing the container (2), designed to close each compartment (11, 12) in a leaktight manner.

Abstract: Cosmetic treatment method for adding fibers to natural eyelashes, comprising: a) applying an adhesive composition (A) to at least part of the eyelashes, b) bringing fibers (12) borne by an applicator (10) into contact with said adhesive composition (A) present on said eyelashes, c) moving the applicator (10) away from the eyelashes, so as to release fibers (12) which adhere to said eyelashes.

Abstract: The present invention relates to a packaging and application device (1) comprising an applicator (20) having an applicator member (23), and a container (10) containing the product to be applied, provided with a wiping member (30) for wiping the applicator member as it is taken out of the container, the wiping member comprising a wiping lip (35) defining a wiping orifice (37) through which the applicator member passes as it is taken out of the container, the wiping lip comprising at least one extension (40) which is directed towards the bottom of the container, is connected to the wiping lip and comes into contact with the applicator member when the latter is withdrawn from the container.

Abstract: This invention relates to a cosmetic product applicator (14) including: —a gripping member (16) extending along a longitudinal axis (A), —a rod carrier (18) arranged in the gripping member (16), —a rod (20) secured to the rod carrier (18) and —a cosmetic product application member (22) carried by the rod (20), the rod carrier being (18) mounted mobile in rotation about the longitudinal axis (A) with respect to the gripping member (16), The rod carrier (18) has a first and a second circumferential linear contact region (86, 90) with the gripping member (16) about the longitudinal axis (A) and a second circumferential linear contact region (86, 90) with the gripping member (16) about the longitudinal axis (A), the rod carrier (18) being arranged totally apart from the gripping member (16) in an intermediate region (92) between the first linear contact region (86) and the second linear contact region (90).

Abstract: Packaging and application device, including: a container containing a product to be applied, a screen through which the product contained in the container exits, the screen having dispensing orifices with different sections, with at least three orifices of which the section varies in a strictly decreasing manner with distance from the centre of the screen.

Abstract: The present invention relates to a device (1) for packaging and applying at least one cosmetic product, comprising: —a container (2) delimiting at least two compartments (11, 12), —a closure cap (3) for closing the container (2), designed to close each compartment (11, 12) in a leaktight manner.

Abstract: Device for packaging and applying eyeliner, including: a container containing the eyeliner to be applied, an applicator tip for applying the eyeliner contained in the container, having two opposite main facets, with a variable width that passes through a maximum, the two facets converging in the direction of the distal end of the applicator tip.

Abstract: The present invention relates to a cosmetic applicator for applying a non-liquid composition (P) to human keratin materials, the applicator: —comprising a stem (7) that extends along a longitudinal axis (X), —defining an internal space (9) that is able to contain the composition (P) to be applied, and —having at least one opening (18) that is in communication with the internal space (9) and leads onto an application surface (8).

Abstract: The present invention relates to a packaging and application device (1) comprising an applicator (20) having an applicator member (23), and a container (10) containing the product to be applied, provided with a wiping member (30) for wiping the applicator member as it is taken out of the container, the wiping member comprising a wiping lip (35) defining a wiping orifice (37) through which the applicator member passes as it is taken out of the container, the wiping lip comprising at least one extension (40) which is directed towards the bottom of the container, is connected to the wiping lip and comes into contact with the applicator member when the latter is withdrawn from the container.

Abstract: Methods and compositions containing oxytocin or an oxytocin analog, specifically carbetocin, are provided for the prevention and treatment of autism spectrum disorders, related disorders and symptoms of such disorders. The methods and compositions of the invention are effective in the treatment of social withdrawal, eye contact avoidance, repetitive behaviors, anxiety, attention deficit, hyperactivity, depression, loss of speech, verbal communication difficulties, aversion to touch, visual difficulties, comprehension difficulties, and sound and light sensitivity. Additional compositions and methods are provided which employ oxytocin or an oxytocin analog in combination with a secondary or adjunctive therapeutic agent to yield more effective treatment tools against autism spectrum disorders and related disorders.

Abstract: Methods for treating metabolic diseases are described for intranasal delivery of an exenatide, comprising an aqueous mixture of exendin, and a delivery enhancer selected from the group consisting of a solubilizer, a chelator, and a surfactant, and the pharmaceutical formulations used therein.

Abstract: Methods and compositions of the invention employ acetylcholinesterase (ACE) inhibitors to prevent and treat diseases and other disorders of the central nervous system (CNS), including Alzheimer's disease. ACE inhibitors are administered for targeted delivery to the CNS, for example by intranasal delivery. The methods and compositions of the present invention yield therapeutic concentrations of ACE inhibitors in a CNS tissue or compartment without the attendant disadvantages, risks and side effects of oral or injection delivery. Exemplary ACE inhibitors for use within the invention include galantamine and various salts and derivatives of galantamine. Carboxylate salts of galantamine (e.g., galantamine gluconate, galantamine lactate, galantamine citrate and galantamine glucarate) described herein exhibit a significant increase in solubility compared to other forms of galantamine, such as galantamine hydrobromide.