Patents by Inventor Alexy Pronin

Alexy Pronin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Expression of functional human olfactory cyclic nucleotide gated (CNG) channel in recombinant host cells and use thereof in cell based assays to identify smell modulators
    Publication number: 20030228633
    Abstract: The present invention relates to isolated nucleic acid sequences that encode human olfactory cyclic nucleotide gated (CNG) channel subunits, and the corresponding polypeptides. The invention further relates to the use of human CNG channels to profile, screen for, and identify compounds that modulate the human olfactory CNG channel. More specifically, the invention relates to the expression of the human olfactory CNG channel in cells, preferably mammalian cells, and the use of these cells in high throughput cell-based assays to identify compounds that enhance or block human olfactory CNG function. Compounds that activate the olfactory CNG channel will enhance smell and can be used to make foods more palatable for individuals with attenuated olfactory function. Conversely, compounds that inhibit the olfactory CNG channel will inhibit smell and can be use to block malodors.
    Type: Application
    Filed: July 8, 2002
    Publication date: December 11, 2003
    Applicant: Senomyx, Inc.
    Inventors: Mark Zoller, Hong Xu, Lena Staszewski, Bryan Moyer, Alexy Pronin, Jon Elliot Adler, Guy Servant, Nicholas Callamaras