Abstract: This invention relates to the use of a pyrazolyl-pyrimidine of the formula (I). n=0, 1, 2 or 3 (I) in the manufacture of a medicament for use in the treatment or prophylaxis of pain. and to their pharmaceutical formulations and to their methods of use.

Abstract: This invention relates to new use of pyrazolyl derivatives and pharmaceutically acceptable salts thereof, which have been found to possess analgesic activity and are accordingly useful in the treatment or prophylaxis of pain conditions in the human or animal body, for example in the manufacture of medicaments for the treatment or prevention of pain in a warm-blooded animal such as man.

Abstract: This invention relates to new use of pyrazolyl derivatives and pharmaceutically acceptable salts thereof, which have been found to possess analgesic activity and are accordingly useful in the treatment or prophylaxis of pain conditions in the human or animal body, for example in the manufacture of medicaments for the treatment or prevention of pain in a warm-blooded animal such as man.

Abstract: The present invention relates to certain spirooxindole derivatives and to pharmaceutically acceptable salts thereof, which exhibit good analgesic properties and are effective in the treatment of chronic pain. The derivatives have the structure of formula I: wherein: Ar is benzene or pyridine; X is NHCO—; —CONH—; or —NH—SO2—; Y is a single bond; and Z is —CH═CHCH2.

Abstract: The present invention relates to certain spirooxindole derivatives of the formula I, and pharmaceutically acceptable salts thereof, which exhibit good analgesic properties and are particularly effective in the treatment of chronic pain.

Abstract: A weight-balancing stand arrangement supports a sheet of material or the like and includes a bottom stand-part and a top stand-part. The top stand-part includes a horizontal beam provided with a horizontal guide surface. The guide surface coacts with widely spaced apart end portions of two guide rods, the opposite end-parts of which are placed closer together and are pivotally mounted on the bottom stand-part and coact with one or more devices which function to forcibly create a clear related rotational pattern for the two guide rods. The arrangement also includes spring devices which act between the bottom stand-part and at least one of the guide rods.