Patents by Inventor Alfio Bertolini

Alfio Bertolini has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8318673
    Abstract: An anti-hemorrhage medication pack for administering an anti-hemorrhage drug, in particular for the treatment of hemorrhage caused by trauma in emergency situations comprises an active ingredient selected from the group comprising the 1-24 amino acid sequence of the adrenocorticotropic hormone (ACTH 1-24) and all its fragments and analogues, and analogues of fragments, with agonist activity on the MC4 melanocortin receptors, and all the synthesis agonists, including those with a nonpeptidic structure, of the MC4 melanocortin receptors. An auto-injector (1; 11) includes the drug for automatically injecting a patient with the drug.
    Type: Grant
    Filed: July 6, 2007
    Date of Patent: November 27, 2012
    Assignee: Health Ricerca e Sviluppo S.R.L.
    Inventors: Giorgio Noera, Alfio Bertolini
  • Publication number: 20090318361
    Abstract: An anti-hemorrhage medication pack for administering an anti-hemorrhage drug, in particular for the treatment of hemorrhage caused by trauma in emergency situations comprises an active ingredient selected from the group comprising the 1-24 amino acid sequence of the adrenocorticotropic hormone (ACTH 1-24) and all its fragments and analogues, and analogues of fragments, with agonist activity on the MC4 melanocortin receptors, and all the synthesis agonists, including those with a nonpeptidic structure, of the MC4 melanocortin receptors. An auto-injector (1; 11) includes the drug for automatically injecting a patient with the drug.
    Type: Application
    Filed: July 6, 2007
    Publication date: December 24, 2009
    Inventors: Giorgio Noera, Alfio Bertolini
  • Patent number: 5380710
    Abstract: Pharmaceutical compositions containing ACTH(1-24) are effective in the treatment of shock conditions and of respiratory and cardiocirculatory insufficiency. The compositions of the invention may be administered by parenteral or inhalatory route at a dosage ranging from 1 to 10 mg of active principle.
    Type: Grant
    Filed: October 11, 1990
    Date of Patent: January 10, 1995
    Inventor: Alfio Bertolini
  • Patent number: 4794104
    Abstract: The parenteral administration of 80-160 .mu.g per kg body weight of substituted or unsubstituted fragments of ACTH (1-39) having formula ACTH (X-Y) wherein X is an integer from 1 to 5 and Y is an integer from 10 to 39 (provided that, when X is 1, Y is not 24) restores the normal blood pressure and respiratory frequence in a patient in serious shock conditions, particularly in hypovolemic shock.
    Type: Grant
    Filed: January 2, 1987
    Date of Patent: December 27, 1988
    Inventor: Alfio Bertolini
  • Patent number: 4794103
    Abstract: Pharmaceutical compositions containing a polypeptide of the cholecystokinin-cerulein group are effective in the treatment of shock conditions and of respiratory and cardiocirculatory insufficiences.The compositions of the invention may be administered by parenteral or inhalatory route at a dosage ranging from 5 to 20 .mu.g of active principle per kg of body weight.
    Type: Grant
    Filed: January 2, 1987
    Date of Patent: December 27, 1988
    Inventor: Alfio Bertolini
  • Patent number: 4291035
    Abstract: Pharmaceutical compositions comprising trimethoprim and a N-ethyl-.gamma.-pyridone-3-carboxylic acid derivative, such as nalidixic, oxolinic or piromidic acid, are more effective than previously known trimethoprim-containing compositions for the treatment of infections affecting the urinary tract.Trimethoprim and the foregoing acid derivatives unpredictably show a noticeable synergistic effect.
    Type: Grant
    Filed: July 11, 1979
    Date of Patent: September 22, 1981
    Assignee: Sigma-Tau Industrie Farmaceutiche Riunite S.p.A.
    Inventor: Alfio Bertolini