Patents by Inventor Alfons Enhsen

Alfons Enhsen has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Carboxyalkoxy-substituted acyl-carboxyphenylurea derivatives and their use as medicaments
    Patent number: 7781459
    Abstract: The invention relates to acyl-carboxyphenylurea derivatives and to their physiologically tolerated salts and physiologically functional derivatives. Compounds of the formula I, in which the radicals have the stated meanings, and the physiological tolerated salts thereof and processes for preparing them are described. The compounds are suitable for example for the treatment of type II diabetes.
    Type: Grant
    Filed: December 20, 2006
    Date of Patent: August 24, 2010
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Elisabeth DeFossa, Dieter Kadereit, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt, Erich Von Roedern, Karl Schoenafinger, Alfons Enhsen
  • Acyl-4-carboxyphenylurea derivatives, processes for preparing them and their use
    Patent number: 7223796
    Abstract: The invention relates to acyl-4-carboxyphenylurea derivatives and to their physiologically tolerated salts and physiologically functional derivatives. The invention particularly relates to compounds of formula I, in which the radicals have the given meanings described herein, and to their physiologically tolerated salts and processes for preparing them. The compounds are, for example, suitable for use as antidiabetics.
    Type: Grant
    Filed: April 10, 2003
    Date of Patent: May 29, 2007
    Assignee: Sanofi-aventis Deutschland GmbH
    Inventors: Elisabeth Defossa, Dieter Kadereit, Karl Schoenafinger, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt, Erich Von Roedern, Alfons Enhsen, Joerg Rieke-Zapp
  • CARBOXYALKOXY-SUBSTITUTED ACYL-CARBOXYPHENYLUREA DERIVATIVES AND THEIR USE AS MEDICAMENTS
    Publication number: 20070088083
    Abstract: The invention relates to acyl-carboxyphenylurea derivatives and to their physiologically tolerated salts and physiologically functional derivatives. Compounds of the formula I, in which the radicals have the stated meanings, and the physiological tolerated salts thereof and processes for preparing them are described. The compounds are suitable for example for the treatment of type II diabetes.
    Type: Application
    Filed: December 20, 2006
    Publication date: April 19, 2007
    Applicant: Sanofi-Aventis Deutschland GmbH
    Inventors: Elisabeth DeFossa, Dieter Kadereit, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt, Erich Von Roedern, Karl Schoenafinger, Alfons Enhsen
  • Carbonylamino-substituted acyl phenyl urea derivatives, process for their preparation and their use
    Patent number: 7179941
    Abstract: The invention relates to compounds of the formula I in which the radicals are defined as specified, and also to their physiologically tolerated salts. The compounds are suitable, for example, as medicaments for preventing and treating type 2 diabetes.
    Type: Grant
    Filed: January 23, 2004
    Date of Patent: February 20, 2007
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Elisabeth Defossa, Dieter Kadereit, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt, Erich Von Roedern, Karl Schoenafinger, Alfons Enhsen
  • Acyl-3-carboxyphenylurea derivatives, processes for preparing them and their use
    Patent number: 7078404
    Abstract: The invention relates to acyl-3-carboxyphenylurea derivatives and to their physiologically tolerated salts and physiologically functional derivatives. The invention relates to compounds of formula I, in which the radicals have the given meanings, and to their physiologically tolerated salts and processes for preparing them. The compounds are, for example, suitable for use as antidiabetics.
    Type: Grant
    Filed: April 10, 2003
    Date of Patent: July 18, 2006
    Assignee: Sanofi-Aventis Deutschland GmbH
    Inventors: Elisabeth Defossa, Dieter Kadereit, Karl Schoenafinger, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt, Erich Von Roedern, Alfons Enhsen
  • Benzothiepine 1, 1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
    Patent number: 7019023
    Abstract: Substituted benzothiepine 1,1-dioxide derivatives of formula I: in which R1, R2, R3, R4, R5 and Z have the meanings indicated, and their physiologically tolerable salts and physiologically functional derivatives and a process for their preparation are described. The compounds are suitable, for example, as hypolipidemics.
    Type: Grant
    Filed: June 27, 2003
    Date of Patent: March 28, 2006
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Wendelin Frick, Alfons Enhsen, Heiner Glombik, Hubert Heuer
  • Carboxamide-substituted phenylurea derivatives, process for their preparation and their use as medicaments
    Publication number: 20050143456
    Abstract: The invention relates to carboxamide-substituted phenylurea derivatives and their physiologically tolerated salts and physiologically functional derivatives. Compounds of the formula I in which the radicals have the stated meanings, and the physiologically tolerated salts thereof and process for their preparation are described. The compounds are suitable, for example, for treating type II diabetes.
    Type: Application
    Filed: November 1, 2004
    Publication date: June 30, 2005
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Elisabeth Defossa, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Erich Roedern, Stefan Peukert, Alfons Enhsen, Armin Bauer, Bernd Neises, Karl Wendt
  • Carbonylamino-substituted acyl phenyl urea derivatives, process for their preparation and their use
    Publication number: 20050014822
    Abstract: The invention relates to compounds of the formula I in which the radicals are defined as specified, and also to their physiologically tolerated salts. The compounds are suitable, for example, as medicaments for preventing and treating type 2 diabetes.
    Type: Application
    Filed: January 23, 2004
    Publication date: January 20, 2005
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Elisabeth Defossa, Dieter Kadereit, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt, Erich Von Roedern, Karl Schoenafinger, Alfons Enhsen
  • Carboxamide-substituted phenylurea derivatives, process for their preparation and their use as medicaments
    Patent number: 6812250
    Abstract: The invention relates to carboxamide-substituted phenylurea derivatives and their physiologically tolerated salts and physiologically functional derivatives. Compounds of the formula I in which the radicals have the stated meanings, and the physiologically tolerated salts thereof and process for their preparation are described. The compounds are suitable, for example, for treating type II diabetes.
    Type: Grant
    Filed: May 24, 2002
    Date of Patent: November 2, 2004
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Elisabeth Defossa, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Erich von Roedern, Stefan Peukert, Alfons Enhsen, Armin Bauer, Bernd Neises, Karl Ulrich Wendt
  • Carboxyalkoxy-substituted acyl-carboxyphenylurea derivatives and their use as medicaments
    Publication number: 20040157922
    Abstract: Carboxyalkoxy-substituted acyl-carboxyphenylurea derivatives and their use as medicaments
    Type: Application
    Filed: October 6, 2003
    Publication date: August 12, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Elisabeth Defossa, Dieter Kadereit, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt, Erich Von Roedern, Karl Schoenafinger, Alfons Enhsen
  • Benzothiepine 1, 1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
    Publication number: 20040087648
    Abstract: Substituted benzothiepine 1,1-dioxide derivatives of formula I: 1
    Type: Application
    Filed: June 27, 2003
    Publication date: May 6, 2004
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Wendelin Frick, Alfons Enhsen, Heiner Glombik, Hubert Heuer
  • Acyl-4-carboxyphenylurea derivatives, processes for preparing them and their use
    Publication number: 20040077716
    Abstract: The invention relates to acyl-4-carboxyphenylurea derivatives and to their physiologically tolerated salts and physiologically functional derivatives.
    Type: Application
    Filed: April 10, 2003
    Publication date: April 22, 2004
    Inventors: Elisabeth Defossa, Dieter Kadereit, Karl Schoenafinger, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt, Erich Von Roedern, Alfons Enhsen, Joerg Rieke-Zapp
  • Acyl-3-carboxyphenylurea derivatives, processes for preparing them and their use
    Publication number: 20030216370
    Abstract: The invention relates to acyl-3-carboxyphenylurea derivatives and to their physiologically tolerated salts and physiologically functional derivatives.
    Type: Application
    Filed: April 10, 2003
    Publication date: November 20, 2003
    Inventors: Elisabeth Defossa, Dieter Kadereit, Karl Schoenafinger, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Karl-Ulrich Wendt, Erich Von Roedern, Alfons Enhsen
  • Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
    Patent number: 6642269
    Abstract: Substituted benzothiepine 1,1-dioxide derivatives of formula I: in which R1, R2, R3, R4, R5 and Z have the meanings indicated, and their physiologically tolerable salts and physiologically functional derivatives and a process for their preparation are described. The compounds are suitable, for example, as hypolipidemics.
    Type: Grant
    Filed: July 24, 2002
    Date of Patent: November 4, 2003
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Wendelin Frick, Alfons Enhsen, Heiner Glombik, Hubert Heuer
  • Carboxamide-substituted phenylurea derivatives, process for their preparation and their use as medicaments
    Publication number: 20030176497
    Abstract: The invention relates to carboxamide-substituted phenylurea derivatives and their physiologically tolerated salts and physiologically functional derivatives.
    Type: Application
    Filed: May 24, 2002
    Publication date: September 18, 2003
    Inventors: Elisabeth Defossa, Thomas Klabunde, Hans-Joerg Burger, Andreas Herling, Erich von Roedern, Stefan Peukert, Alfons Enhsen, Armin Bauer, Bernd Neises, Karl Ulrich Wendt
  • Substituted 1,3-diaryl-2-pyrid-2-yl-3-(pyrid-2-ylamino)propanol derivatives, process for their preparation, pharmaceuticals comprising these compounds and their use
    Patent number: 6596728
    Abstract: Substituted 1,3-diaryl-2-pyridin-2-yl-3-(pyridin-2-ylamino)propanol derivatives of the formula (I), and salts thereof, in which the radicals have the meanings given in the specification, and physiologically tolerated salts thereof and processes for their preparation are described. The compounds are suitable, for example, as hypolipidemic agents.
    Type: Grant
    Filed: October 1, 1999
    Date of Patent: July 22, 2003
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Reinhard Kirsch, Alfons Enhsen, Heiner Glombik, Werner Kramer, Eugen Falk
  • Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
    Publication number: 20030017996
    Abstract: Substituted benzothiepine 1,1-dioxide derivatives of formula I: 1
    Type: Application
    Filed: July 24, 2002
    Publication date: January 23, 2003
    Applicant: Aventis Pharma Deutschland GmbH
    Inventors: Wendelin Frick, Alfons Enhsen, Heiner Glombik, Hubert Heuer
  • Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
    Patent number: 6441022
    Abstract: Substituted benzothiepine 1,1-dioxide derivatives of formula I: in which R1, R2, R3, R4, R5 and Z have the meanings indicated, and their physiologically tolerable salts and physiologically functional derivatives and a process for their preparation are described. The compounds are suitable, for example, as hypolipidemics.
    Type: Grant
    Filed: February 2, 2001
    Date of Patent: August 27, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Wendelin Frick, Alfons Enhsen, Heiner Glombik, Hubert Heuer
  • Benzo(b)thiepine-1,1-dioxide derivatives, a method for the production thereof, medicaments containing these compounds, and their use
    Patent number: 6387944
    Abstract: The invention relates to substituted benzo(b)thiepine-1,1-dioxide derivatives and to the acid addition salts thereof. The invention relates to compounds of formula (I), wherein R1, R2, R3, R4, R5 and Z have the cited descriptions, to the physiologically compatible salts, to physiologically functional derivatives, and to a method for the production thereof. The compounds are suited, for example, as hypolipidemic agents.
    Type: Grant
    Filed: December 7, 2000
    Date of Patent: May 14, 2002
    Assignee: Aventis Pharma Deutschland GmbH
    Inventors: Wendelin Frick, Alfons Enhsen, Heiner Glombik, Hubert Heuer
  • Benzothiepine 1,1-dioxide derivatives, a process for their preparation, pharmaceuticals comprising these compounds, and their use
    Publication number: 20020045583
    Abstract: Substituted benzothiepine 1,1-dioxide derivatives of formula I: 1
    Type: Application
    Filed: February 2, 2001
    Publication date: April 18, 2002
    Applicant: Hoechst Marion Roussel Deutschland
    Inventors: Wendelin Frick, Alfons Enhsen, Heiner Glombik, Hubert Heuer