Abstract: The invention relates to a method and an optical transmission system for compensation of dispersion in optical transmission lines in which dispersion compensation fibers are applied, with the dispersion compensation fibers being arranged at the beginning as well as at the end of the line segments of the optical fibers forming the transmission line. The signal distortions due to non-linear effects are reduced by making use of the recognition that non-linearities should only occur at as small as possible an accumulated dispersion. This is obtained by an unequal division of the dispersion compensation fiber applied for the compensation of the dispersion of the optical fiber, with the part of the dispersion compensation fiber attached at the beginning of a line segment being directly connected to the optical fiber and having an accumulated dispersion which is smaller as to amount than the accumulated dispersion of the part of the dispersion compensation fiber attached at the end of the optical fiber.