Patents by Inventor Alfonso Baldi

Alfonso Baldi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240156744
    Abstract: Method for loading various molecules into plant-derived nanovesicles, comprising the following steps: a. suspending the isolated nanovesicles in a phosphate buffered saline; b. analyzing the suspended nanovesicles with a technique called “Nanoparticle Tracking Analysis” using a “Nanosight” for the evaluation of concentration and size distribution; c. re-suspending the nanovesicles in phosphate buffered saline; d. transferring the nanovesicles to sterile means; e. adding the fluorescent chemical to be loaded; f. treating the nanovesicles in the sterile means to facilitate the entry of the molecule to be loaded through their cell membrane; g. transferring the nanovesicles loaded with the desired molecule into ultra¬centrifuge tubes; h. re-suspending the pellet containing the nanovesicles in phosphate buffered saline and storing the supernatant obtained from the ultracentrifugation as a control for subsequent analysis; i. re-suspending the nanovesicles in phosphate buffered saline and proceed with testing.
    Type: Application
    Filed: March 23, 2022
    Publication date: May 16, 2024
  • Publication number: 20230023462
    Abstract: The invention according to the present document discloses a device 1 configured for conveying a toxic aerosol from a drug contained in a syringe (S) or in a vial (F) toward a suction pipe, comprising a cylindrical hollow element comprising an inner space configured for accommodating a syringe so that the inner walls of said space slidingly adhere to the outer walls of the syringe barrel, provided with a proximal end 2.10 which includes an opening 2.6 configured in such a way as to allow the insertion of a syringe barrel, and a flange configured for accommodating a syringe flange, and a distal end 2.11 which includes an opening 2.7 configured in such a way as to allow the cone, fitting, and needle of said syringe to pass through, and a cap configured for being connected to said cylindrical hollow element present in two configurations, one suitable for administering a drug and another suitable for taking a drug from a vial, in particular a drug potentially releasing a toxic aerosol.
    Type: Application
    Filed: December 30, 2019
    Publication date: January 26, 2023
    Inventors: Enrico Pierluigi Spugnini, Alfonso Baldi
  • Patent number: 9861711
    Abstract: The present invention relates to isolated ligands of anti-Mullerian hormone marked so as to be directly detectable by means of magnetic resonance imaging in the endometriosic lesions. In particular, such ligands can be used in a method for diagnosing in vivo endometriosis wherein said method comprises a passage of localizing and/or evaluating the entity of the endometriosic lesions in a patient.
    Type: Grant
    Filed: August 4, 2014
    Date of Patent: January 9, 2018
    Inventors: Pietro Giulio Signorile, Alfonso Baldi
  • Publication number: 20160184463
    Abstract: The present invention relates to isolated ligands of anti-Mullerian hormone marked so as to be directly detectable by means of magnetic resonance imaging in the endometriosic lesions. In particular, such ligands can be used in a method for diagnosing in vivo endometriosis wherein said method comprises a passage of localizing and/or evaluating the entity of the endometriosic lesions in a patient.
    Type: Application
    Filed: August 4, 2014
    Publication date: June 30, 2016
    Inventors: Pietro Giulio SIGNORILE, Alfonso BALDI
  • Publication number: 20150141276
    Abstract: The present description relates to an in vitro method for the diagnosis of endometriosis, an in vitro method for the monitoring of endometriosis and a kit for the diagnosis of endometriosis and/or for the monitoring of endometriosis in a subject.
    Type: Application
    Filed: May 13, 2013
    Publication date: May 21, 2015
    Inventors: Pietro Giulio Signorile, Alfonso Baldi