Patents by Inventor Alfonso Fernandez

Alfonso Fernandez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 8989567
    Abstract: A three-dimensional (3D) scanner device for generating a three dimensional (3D) surface model of shaped objects, such as dental structures, applicable for use in the field of dentistry, particularly to dental prosthetics manufacturing. Methods and systems relating to the device are also disclosed.
    Type: Grant
    Filed: May 23, 2014
    Date of Patent: March 24, 2015
    Inventors: Alfonso Fernandez Pulido, David De Pablos Garcia
  • Publication number: 20130183358
    Abstract: Liposomes with cosmetic and/or dermopharmaceutical ingredients for the care of the skin, scalp and/or hair and their use in washing agents and/or sprays for the treatment of textile materials.
    Type: Application
    Filed: August 17, 2012
    Publication date: July 18, 2013
    Applicant: LIPOTEC, S.A.
    Inventors: Alfonso Fernandez Botello, Joseph-Lluis Viladot Petit, Raquel Delgado Gonzalez
  • Publication number: 20130064876
    Abstract: A process of treatment of textile materials containing microcapsules of active ingredients, the fibers and/or textile materials resulting from this process and their cosmetic or pharmaceutical use and/or their use as a repellent.
    Type: Application
    Filed: March 24, 2011
    Publication date: March 14, 2013
    Applicant: LIPOTEC S.A.
    Inventors: Josep LLuis Viladot Petit, Raquel Delgado Gonzalez, Alfonso Fernández Botello
  • Publication number: 20130017239
    Abstract: A delivery system for active ingredients which comprises lipid nanoparticles, such as solid lipid nanoparticles (SLN) or nanostructured lipid carriers (NLC), polymerically coated, and their use in the preparation of pharmaceutical, cosmetic and/or alimentary compositions.
    Type: Application
    Filed: March 24, 2011
    Publication date: January 17, 2013
    Applicant: LIPOTEC S.A.
    Inventors: Josep LLuis Viladot Petit, Raquel Delgado Gonzalez, Alfonso Fernández Botello
  • Publication number: 20120183982
    Abstract: The test of the invention comprises the measuring the total amount of xylose in urine and/or its concentration in blood following oral administration of 4-O-?-D-galactopyranosyl-D-xylose (4-GX) to the patient. It is a non-invasive test that is based on the direct evaluation of the global enzyme activity in the whole individual, not on measuring the metabolic consequences derived from its deficiency. It does not require specialised equipment, does not cause apparent discomfort in patients with lactase deficiency and is very reliable, thus overcoming the drawbacks of the diagnostic tests currently in use and is a statistically significantly better test in terms of its reliability; consequently it should become the reference or gold standard test for the indication of hypolactasia.
    Type: Application
    Filed: January 13, 2012
    Publication date: July 19, 2012
    Applicant: VENTER PHARMA, S.L.
    Inventors: Juan José ARAGÓN REYES, Alfonso FERNANDEZ-MAYORALAS ALVAREZ, Carmen HERMIDA DIAZ
  • Patent number: 7537909
    Abstract: An enzymatic process to obtain 4-O-?-D-galactopyranosyl-D-xylose useful in compositions or solutions in the in vivo evaluation of intestinal lactose activity in humans, that comprises the steps of preparing a reaction mixture of D-xylose, a ?-D-galactopyranoside and a reaction medium that comprises water buffered to a pH between 5.0 and 9.0; adding 10 to 1,000 units of ?-D-galactosidase per gram of ?-D-galactopyranoside; subjecting the reaction mixture to a reaction or a temperature between a temperature higher than the freezing point of the reaction mixture and 45° C., for 2 to 48 hours; for the reaction by deactivation of the ?-D-galactosidase; and to isolate and crystallize the fractions that contain 4-O-?-D-galactopyranosyl-D-xylose from a crystallization mixture selected between mixtures of acetone/methanol in a ratio between 5/1 to 20/1 and mixtures of acetone/water in a ratio between 5/1 to 20/1.
    Type: Grant
    Filed: December 17, 2003
    Date of Patent: May 26, 2009
    Assignees: Consejo Superior de Investigaciones Cientificas, Universidad Autonoma de Madrid
    Inventors: Francisco Javier Cañada Vicinay, Guillerno Corrales Morales, Alfonso Fernández-Mayoralas Alvarez, Manuel Martín Lomas, Juan José Aragón Reyes
  • Publication number: 20090095267
    Abstract: The inventive apparatus relates to a magnetic apparatus comprising vanes and grooves for fuel supply treatment. The inventive apparatus consists of a tubular device which is installed in the fuel supply line and which houses a second tube. According to the inventive apparatus, the second tube in turn contains a series of magnets with opposing poles and is surrounded by a helical sheet or vanes, said inner tube and the helical sheet or vanes being equipped with holes and micro holes, and grooves, in order to generate a centrifugal action in the fuel while its molecules are polarized by the magnets.
    Type: Application
    Filed: March 3, 2005
    Publication date: April 16, 2009
    Inventor: Alfonso Fernandez De La Torre
  • Patent number: 7206278
    Abstract: A method, system, and device are provided for increasing the total amount of useful information transmitted in a radio communication system. The method includes receiving a selection signal with which a cluster is selected; receiving data streams of information from at least two subscribers so that the streams have identical characteristics; dividing the data streams into a plurality of bit streams in order to form bit groupings through the selection of at least one bit from each one of said bit streams, for the purpose of carrying out the allocation of a state to each one of the groupings formed. Each state is associated with the cluster selected. Thereafter, the components that define the states are transmitted using orthogonal frequency division multiplexing (OFDM).
    Type: Grant
    Filed: September 17, 2001
    Date of Patent: April 17, 2007
    Assignee: Alcatel
    Inventor: Alfonso Fernandez Duran
  • Patent number: 7164664
    Abstract: System that allocates a carrier frequency to a radio link, for transmitting data bursts between a remote unit and a fixed unit, by employing orthogonal frequency division multiplexing OFDM. The fixed unit records a predetermined number of parameters relative to the communication in course, for the purpose of weighting said parameters, such as number of errors in the radio link and number of retransmissions or the like, and allocates to these parameters a probability level. The fixed unit allocates a probability level to each carrier frequency, so that it responds to a communication set-up request allocating the carrier frequency with the highest probability.
    Type: Grant
    Filed: December 3, 2001
    Date of Patent: January 16, 2007
    Assignee: Alcatel
    Inventors: Alfonso Fernandez Duran, Francisco Escrihuela Langa
  • Publication number: 20050238580
    Abstract: The invention relates to the use in humans of a method which is based on the use of 4-galactosyl-xylose and which involves an alternative technique to evaluate xylose in urine. The method consists of measuring the concentration of xylose in the blood following the oral administration of 4-galactosyl-xylose to the patient, the use of said method being even more suitable in the case of newborns. The invention also relates to the technology used for the in vivo evaluation of intestinal lactase activity, by way of a non-invasive test for the diagnosis of a deficiency of said enzyme, which consists of directly evaluating the overall activity of the enzyme in the individual and not in assessing the consequences of said deficiency. The inventive method does not require specialized equipment, does not cause any obvious discomfort to patients with a lactase deficiency and is extremely reliable, thereby eliminating the inconveniences of currently used diagnostic tests.
    Type: Application
    Filed: April 13, 2005
    Publication date: October 27, 2005
    Inventors: Juan Aragon Reyes, Alfonso Fernandez-Mayoralas Alvarez
  • Publication number: 20050069535
    Abstract: The present invention is related to the field of immunology and more specifically with immunotherapeutic combinations used for controlling growth and/or cell proliferation of tumors. By means of the present invention a therapeutic effect against tumors is observed by the combination of idiotypic vaccines whose principle active is an anti-ganglioside antibody (Ab1), with idiotypic vaccines whose principle active is anti-idiotype antibody (Ab2) obtained against an anti-ganglioside antibody, or vaccines whose principle active is one or more gangliosides. Combinations of these vaccines are described that cause a synergic therapeutic effect against tumors. The referred combinations can be applied to patients in different clinical conditions of tumors that express gangliósidos.
    Type: Application
    Filed: April 8, 2002
    Publication date: March 31, 2005
    Inventors: Luis Fernandez Molina, Ana Vazquez Lopez, Rolando Perez Rodriguez, Adriana Carr Perez, Yildian Diaz Rodriguez, Mauro Alfonso Fernandez
  • Publication number: 20040241811
    Abstract: An enzymatic process to obtain 4-O-&bgr;-D-galactopyranosyl-D-xylose useful in compositions or solutions in the in vivo evaluation of intestinal lactose activity in humans, that comprises the steps of preparing a reaction mixture of D-xylose, a &bgr;-D-galactopyranoside and a reaction medium that comprises water buffered to a pH between 5.0 and 9.0; adding 10 to 1,000 units of &bgr;-D-galactosidase per gram of &bgr;-D-galactopyranoside; subjecting the reaction mixture to a reaction or a temperature between a temperature higher than the freezing point of the reaction mixture and 45° C., for 2 to 48 hours; for the reaction by deactivation of the &bgr;-D-galactosidase; and to isolate and crystallize the fractions that contain 4-O-&bgr;-D-galactopyranosyl-D-xylose from a crystallization mixture selected between mixtures of acetone/methanol in a ratio between 5/1 to 20/1 and mixtures of acetone/water in a ratio between 5/1 to 20/1.
    Type: Application
    Filed: December 17, 2003
    Publication date: December 2, 2004
    Inventors: Francisco Javier Canada Vicinay, Guillerno Corrales Morales, Alfonso Fernandez-Mayorales Alvarez, Manuel Martin Lomas, Juan Jose Aragon Reyes
  • Publication number: 20020067703
    Abstract: System that allocates a carrier frequency to a radio link, for transmitting data bursts between a remote unit (14) and a fixed unit (11), by employing orthogonal frequency division multiplexing OFDM. The fixed unit (11) records a predetermined number of parameters relative to the communication in course, for the purpose of weighting said parameters, such as number of errors in the radio link and number of retransmissions or the like, and allocates to these parameters a probability level.
    Type: Application
    Filed: December 3, 2001
    Publication date: June 6, 2002
    Applicant: ALCATEL
    Inventors: Alfonso Fernandez Duran, Francisco Escrihuela Langa
  • Publication number: 20020034175
    Abstract: Method for increasing the total amount of useful information (throughput) transmitted in a radiocommunication system in which are performed the functions of: reception of a selection signal with which a cluster is selected; reception of data streams of information from at least two subscribers so that said streams have identical characteristics; division of said data streams into a plurality of bit streams in order to form bit groupings through the selection of at least one bit from each one of said bit streams, for the purpose of carrying out the allocation of a state to each one of the groupings formed. Each state is associated with the cluster selected. Thereafter, the components that define the states are transmitted using orthogonal frequency division multiplexing (OFDM).
    Type: Application
    Filed: September 17, 2001
    Publication date: March 21, 2002
    Applicant: ALCATEL
    Inventor: Alfonso Fernandez Duran
  • Patent number: 6285859
    Abstract: A method for predistorting a signal sent from a first unit (U1) to a second unit, the first unit (U1) sending data to the second unit (U2) through a first channel and the second unit (U2) sending data to the first unit (U1) through a second channel. The method comprises the computing (53) of representative coefficients of the second channel (H2) on the basis of a second predetermined sequence sent (52) from the second unit (U2) to the first unit (U1). According to the method, the first unit (U1) sends a first predetermined sequence to the second unit (U2) which sends it back in the form received to the first unit (U1), in the form of a return sequence. The first unit (U1) computes representative coefficients of the first and second channels jointly (H1, H2) on the basis of the returned sequence received. The signal sent by the first unit is predistorted according to the representative coefficients of the channel and the said representative coefficients of the first and second channels jointly.
    Type: Grant
    Filed: February 5, 1999
    Date of Patent: September 4, 2001
    Assignee: Alcatel
    Inventors: Alfonso Fernández Durán, Gregorio Núñez León De Santos
  • Publication number: 20010000703
    Abstract: The present invention refers to a transmission/reception unit that exchanges data with a remote unit by means of a channel using distributed modulation/demodulation treatment means. The transmission/reception unit includes equalization means (23) to equalize a first signal received from said remote unit and predistortion means to predistort a second signal transmitted to said remote unit. According to the invention, the unit is characterized in that the modulation/demodulation treatment means operate in a non-linear way and the unit includes means (230) to store information that is representative of a non-linear distortion of said modulation/demodulation treatment means and which defines a non-linear reference, and means (233) to adjust coefficients (CO) in the equalization means (23) according to the signal received from the remote unit and said representative information, the mentioned adjusted coefficients being transmitted to said predistortion means.
    Type: Application
    Filed: December 20, 2000
    Publication date: May 3, 2001
    Inventors: Gregorio Nunez Leon De Santos, Jose Manuel Paez Borrallo, Javier Casajus Quiros, Rafael Burriel Lluna, Alfonso Fernandez Duran
  • Patent number: 6205170
    Abstract: The present invention refers to a transmission/reception unit that exchanges data with a remote unit by means of a channel using distributed modulation/demodulation treatment means. The transmission/reception unit includes equalization means (23) to equalize a first signal received from said remote unit and predistortion means to predistort a second signal transmitted to said remote unit. According to the invention, the unit is characterized in that the modulation/demodulation treatment means operate in a non-linear way and the unit includes means (230) to store information that is representative of a non-linear distortion of said modulation/demodulation treatment means and which defines a non-linear reference, and means (233) to adjust coefficients (CO) in the equalization means (23) according to the signal received from the remote unit and said representative information, the mentioned adjusted coefficients being transmitted to said predistortion means.
    Type: Grant
    Filed: March 10, 1998
    Date of Patent: March 20, 2001
    Assignee: Alcatel
    Inventors: Gregorio Núñez León De Santos, José Manuel Paez Borrallo, Javier Casajús Quirós, Rafael Burriel Lluna, Alfonso Fernández Durań
  • Patent number: 6101219
    Abstract: An adaptive equaliser particularly for equalising digital signals with analogue modulation, where use is made of a training sequence formed by a previously known sequence of symbols which is applied to said equaliser simultaneously with the demodulated signal present in the receiver. In this way a first estimate is made of the coefficients of the filter or filters of the equaliser that compensate the linear distortions in the transmission channel. The training sequence (TS), before being used in the equaliser (CEQ), is first applied to a lowpass filter whose transfer function is the same as that of the premodulation filter employed in the modulator. This transfer function also incorporates distortion effects, both linear and non-linear, to which the data are subjected in the receive side when they have been demodulated prior to their detection or regeneration.
    Type: Grant
    Filed: September 10, 1996
    Date of Patent: August 8, 2000
    Assignee: Alcatel NV
    Inventors: Mariano Perez Abadia, Gregorio Nunez Leon De Santos, Alfonso Fernandez Duran
  • Patent number: 5994092
    Abstract: There is disclosed the use of O-.beta.-D-galactopyranosyl-D-xyloses, particularly 2-O-.beta.-D-galactopyranosyl-D-xylose and 3-O-.beta.-D-galactopyranosyl-D-xylose, for the preparation of compositions and solutions intended to the evaluation of the intestinal lactase, which present an affinity to the substantially enchanced lactase. There is also disclosed a process for producing O-.beta.-D-galactopyranosyl-D-xyloses, comprising: reacting a D-xylose and a substrate of .beta.-D-galactopyranosyl in the presence of an enzyme .beta.-galactosidase, in an aqueous medium buffered to a pH comprised between 5.0 and 9.0 and at temperature between 4 and 37.degree. C., deactivating the .beta.-galactosidase by heating at 100.degree. C. when reaching the maximum yield of formation of disaccharides detected through thin layer chromatography, and isolating the formed disaccharides through filtration in a packed column with a thinner selected between water and water/alcohol.
    Type: Grant
    Filed: November 4, 1997
    Date of Patent: November 30, 1999
    Assignees: Universidad Autonoma, Consejo Superior Investigaciones Cientificas
    Inventors: Juan Jose Aragon Reyes, Francisco Javier Canada Vicinay, Alfonso Fernandez-Mayoralas Alvarez, Rosa Lopez Alvarez, Manuel Martin Lomas, Daniel Villanueva Torregroza
  • Patent number: 5817513
    Abstract: The present invention relates to immunotherapy strategies for the treatment of malignancies. The present immunotherapy strategies have gangliosides as a target. Gangliosides are glycosphingolipids which are present on normal cells and on malignant cells. On malignant cells they are more abundant and expressed in a different organization and conformation. The present invention provides antibodies which recognize these gangliosides, which antibodies are specific, have recurrent idiotypes and have value as immunoregulators. The invention further provides anti-idiotypic antibodies against anti-ganglioside antibodies. These are useful in vaccination strategies.
    Type: Grant
    Filed: December 9, 1994
    Date of Patent: October 6, 1998
    Assignee: Centro de Inmunologia Molecular
    Inventors: Ana Maria Vazguez Lopez, Angel Mauro Alfonso Fernandez, Rolando Perez Rodriguez, Amparo E. Macias Abraham, Carlos Manuel Alvarez Valcarcel, Maria Eliana Lanio Ruiz