Abstract: A system for processing biological specimens mounted on microscope slides by adding and removing processing fluids from microscope slides by means of capillary action using a slide holder capable of holding multiple microscope slides, and a spacer positioned in between two slides of a slide pair to create a capillary gap. A capillary gap adjuster can be used to pinch and release one end of the slide pair to create a pulsatile action to mix the reagent within the capillary gap. The system may further include a reagent holder, an absorbent pad, a series of reagent baths, and an incubator for holding one or more slide holders.

Abstract: A system for processing biological specimens mounted on microscope slides by adding and removing processing fluids from microscope slides by means of capillary action using a slide holder capable of holding multiple microscope slides, and a spacer positioned in between two slides of a slide pair to create a capillary gap. A capillary gap adjuster can be used to pinch and release one end of the slide pair to create a pulsatile action to mix the reagent within the capillary gap. The system may further include a reagent holder, an absorbent pad, a series of reagent baths, and an incubator for holding one or more slide holders.

Abstract: The preparation and use of stable, ready-to-use substrate-chromogen solutions for the detection and quantification of peroxidase or pseudoperoxidase activity are described. The substrate-chromogen solution according to the present invention contains a buffer, preferably imidazole buffer, a polymer, a hydroperoxide substrate, a chromogenic organic electron donor and electron donor of the carbohydrate type as a stabilizer. The substrate-chromogen solution retains its full peroxidatic activity and develops a negligible color during storage.