Abstract: The aim of the invention is to provide an electrochemical cell which is as simply constructed as possible and which requires as little production effort as possible. This is achieved by an electrochemical cell, in which a first connection conductor is secured to a cover element in a first connection region by means of a first potting element, said first potting element being surrounded and/or accommodated by a first compensation element of the electrochemical cell in the first connection region, and/or in which a second connection conductor is secured to the cover element in a second connection region by means of a second potting element, said second potting element being surrounded and/or accommodated by a second compensation element of the electrochemical cell in the second connection region.

Abstract: The invention relates to a process for the preparation of compounds of formula (I), which are useful intermediates in the synthesis of Upadacitinib and structurally related compounds, by using Weinreb amide (III), or an equivalent thereof, as key intermediate.

Abstract: A process for preparing compounds of formula (I), or a salt or solvate thereof, including Brexpiprazole, which process comprises cyclization of a compound of formula (II) or (III), or a salt or solvate thereof. The invention also refers to intermediates of said process.

Abstract: A method and system for formulating a required composition in order to produce a determined product from the supply of at least one ingredient that has a time-varying composition; the method has the steps of: (a) pre-establishing a final profile of components of the required composition; (b) providing a first ingredient and a second ingredient, where at least one of them has a time-varying composition; (c) determining an initial profile of components of the first ingredient and the second ingredient; (d) estimating an amount of the first ingredient and the second ingredient to be supplied; (e) supplying, simultaneously or sequentially, the estimated amount of the first ingredient and the second ingredient, and simultaneously, in-line and/or in real-time, generating a real-time profile of components of the amount of the first ingredient and the second ingredient as they are being supplied; (f) determining in-line or in real-time whether the amount of the first ingredient and/or the amount of the second ingredi

Abstract: The present invention relates to new and improved processes for the preparation of deoxycholic acid (DCA) and pharmaceutically acceptable salts thereof, as well as to novel intermediates useful for the preparation of DCA and pharmaceutically acceptable salts thereof.

Abstract: A process for the preparation of obeticholic acid and derivatives thereof by: (a) hydrogenation of the double bond and reductive opening of the epoxide of a compound of formula (II) or a salt or solvate thereof to obtain a compound of formula (IIIa) and/or (IIIb), or salts or solvates thereof and (b) conversion of a compound of formula (IIIa) and/or a compound of formula (IIIb), or a salt or solvate thereof, into a compound of formula (I), or a salt or solvate thereof

Abstract: An edible and thermoreversible oleogel comprising an oil or mixture of oils, grease or mixtures of fats and a structuring agent or mixture of structuring agents on the basis of a distilled monoglyceride of saturated fatty acid having from 12 to 24 carbon atoms that contains more than 90% by weight of monoglycerides, the monoglycerides of the saturated fatty acid are at least 40% by weight of monoglycerides of stearic acid and at least 30% by weight of monoglycerides of palmitic acid. The oleogel is prepared by the combination of oil, grease, and the structuring agent followed by a heating of the mixture, which is then cooled to obtain the oleogel. The resulting oleogel can be used as a substitute for fat in food products.

Abstract: The present invention relates to new and improved processes for the preparation of deoxycholic acid (DCA) and pharmaceutically acceptable salts thereof, as well as to DCA and pharmaceutically acceptable salts thereof, the carbon atoms of which are derived partially or solely from plant sources.

Abstract: A process for preparing compounds of formula (I), or a salt or solvate thereof, including Brexpiprazole, which process comprises cyclization of a compound of formula (II) or (III), or a salt or solvate thereof. The invention also refers to intermediates of said process.

Abstract: A process for the preparation of obeticholic acid and derivatives thereof by: (a) hydrogenation of the double bond and reductive opening of the epoxide of a compound of formula (II) or a salt or solvate thereof to obtain a compound of formula (IIIa) and/or (IIIb), or salts or solvates thereof and (b) conversion of a compound of formula (IIIa) and/or a compound of formula (IIIb), or a salt or solvate thereof, into a compound of formula (I), or a salt or solvate thereof

Abstract: A process for preparing compounds of formula (I), or a salt or solvate thereof, including Brexpiprazole, which process comprises cyclization of a compound of formula (II) or (III), or a salt or solvate thereof. The invention also refers to intermediates of said process.

Abstract: An additive manufacturing system includes a printing surface for supporting a printed part, and a part removal system, including at least one wire configured to move relative to the printing surface and configured to engage the printed part for removing the printed part from the printing surface. In another embodiment, an additive manufacturing system includes a printing surface for supporting a printed part, and a part removal system, including at least one saw configured to move relative to the printing surface and configured to engage the printed part for removing the printed part from the printing surface.

Abstract: An additive manufacturing system includes a hopper for containing a feedstock, at least one helical drive positioned downstream from the hopper for receiving the feedstock therefrom, a heat source positioned proximate at least a portion of the at least one helical drive, and an outlet. The at least one helical drive is configured to advance the feedstock toward the outlet, the heat source is configured to at least partially liquefy the feedstock advanced by the at least one helical drive, and the outlet is configured to dispense the at least partially liquefied feedstock based on a desired toolpath. The at least one helical drive may include at least one of a screw, a bolt, an auger, or an Archimedean screw.

Abstract: An additive manufacturing system includes performing at least one first 3D printing process to at least partially manufacture an artifact, measuring at least one measured dimension of the at least partially manufactured artifact, and comparing the at least one measured dimension to at least one corresponding nominal dimension to provide at least one comparison. The process also includes generating at least one regression model in response to the at least one comparison.

Abstract: A process for preparing compounds of formula (I), or a salt or solvate thereof, including Brexpiprazole, which process comprises cyclization of a compound of formula (II) or (III), or a salt or solvate thereof. The invention also refers to intermediates of said process.

Abstract: An edible and thermoreversible oleogel comprising an oil or mixture of oils, grease or mixtures of fats and a structuring agent or mixture of structuring agents on the basis of a distilled monoglyceride of saturated fatty acid having from 12 to 24 carbon atoms that contains more than 90% by weight of monoglycerides, the monoglycerides of the saturated fatty acid are at least 40% by weight of monoglycerides of stearic acid and at least 30% by weight of monoglycerides of palmitic acid. The oleogel is prepared by the combination of oil, grease, and the structuring agent followed by a heating of the mixture, which is then cooled to obtain the oleogel. The resulting oleogel can be used as a substitute for fat in food products.

Abstract: The present invention relates to new and improved processes for the preparation of deoxycholic acid (DCA) and pharmaceutically acceptable salts thereof, as well as to novel intermediates useful for the preparation of DCA and pharmaceutically acceptable salts thereof.

Abstract: The present invention relates to new and improved processes for the preparation of deoxycholic acid (DCA) and pharmaceutically acceptable salts thereof, as well as to DCA and pharmaceutically acceptable salts thereof, the carbon atoms of which are derived solely from plant sources.

Abstract: In various embodiments, magnetic materials are fabricated in layer-by-layer fashion via additive manufacturing techniques.

Abstract: An electric and/or telecommunications cables having retro-reflective integral covers to be used in harsh environments with low or null visibility and the manufacturing process thereof. The cable comprises a core capable of incorporating a plurality of electric and/or telecommunications conductors, reinforcement elements and/or filler elements; a first protective cover layer wrapping the core; at least one reflective tape including visible external light retro-reflective elements, and wrapping the first protective cover layer, which constitutes a second cover layer; and a third protective cover layer wrapping the second cover layer, constituted by the reflective tape having retro-reflective elements and the first protective cover layer.