Patents by Inventor Alfonzo D. Jordan

Alfonzo D. Jordan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Substituted benzothiazole and benzoxazole derivatives useful as inhibitors of DPP-1
    Patent number: 8481547
    Abstract: The present invention is directed to substituted benzothiazole and benzoxazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by DPP-1.
    Type: Grant
    Filed: December 16, 2010
    Date of Patent: July 9, 2013
    Assignee: Janssen Pharmaceutica NV
    Inventors: Alfonzo D. Jordan, Renee L. DesJarlais, Dennis J. Hlasta, Michael H. Parker, Carsten Schubert, Kimberly White
  • 2-amino-quinazoline derivatives useful as inhibitors of ?-secretase (BACE)
    Patent number: 8426429
    Abstract: The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE.
    Type: Grant
    Filed: August 4, 2005
    Date of Patent: April 23, 2013
    Assignee: Jansssen Pharmaceutica N.V.
    Inventors: Ellen Baxter, Robert Boyd, Steven J. Coats, Alfonzo D. Jordan, Allen B. Reitz, Charles H. Reynolds, Mark Schulz, Malcolm Scott
  • 2-amino-quinazoline derivatives useful as inhibitors of ?-secretase (BACE)
    Patent number: 8383637
    Abstract: The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE.
    Type: Grant
    Filed: August 4, 2005
    Date of Patent: February 26, 2013
    Assignee: Jansssen Pharmaceutica N.V.
    Inventors: Ellen Baxter, Francois Paul Bischoff, Robert E. Boyd, Mirielle Braeken, Steve Coats, Yifang Huang, Alfonzo D. Jordan, Chi Luo, Marc Hubert Mercken, Serge Maria Aloysius Pieters, Allen B. Reitz, Charles H. Reynolds, Tina Morgan Ross, Brett A. Tounge, Mark J. Schulz, Hans Louis Jos De Winter
  • SUBSTITUTED BENZOTHIAZOLE AND BENZOXAZOLE DERIVATIVES USEFUL AS INHIBITORS OF DPP-1
    Publication number: 20110152287
    Abstract: The present invention is directed to substituted benzothiazole and benzoxazole derivatives, pharmaceutical compositions containing them and their use in the treatment of disorders and conditions modulated by DPP-1.
    Type: Application
    Filed: December 16, 2010
    Publication date: June 23, 2011
    Inventors: Alfonzo D. Jordan, Renee L. DesJarlais, Dennis J. Hlasta, Michael H. Parker, Carsten Schubert, Kimberly White
  • Neurotrophic pyrrolidines and piperidines, and related compositions and methods
    Patent number: 6809107
    Abstract: This invention provides compounds having the following general structures: This invention also provides pharmaceutical compositions comprising same and methods of using these compositions to treat and prevent disorders characterized by neuronal damage.
    Type: Grant
    Filed: June 14, 2000
    Date of Patent: October 26, 2004
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Ramesh M. Kanojia, Alfonzo D. Jordan, Allen B. Reitz, Mark J. Macielag, Boyu Zhao
  • 5-?(heteroaryl)alkyl!-3-oxo-pyrido?1,2-a!benzimidazole-4-carboxamide derivatives useful in treating central nervous system disorders
    Patent number: 5922731
    Abstract: A compound of the general formula 1; ##STR1## is disclosed as useful in treating disorders of the central nervous system. Pharmaceutical compositions and methods of treatment are also disclosed.
    Type: Grant
    Filed: June 30, 1997
    Date of Patent: July 13, 1999
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Allen B. Reitz, Louis J. Fitzpatrick, Alfonzo D. Jordan, Pauline J. Sanfilippo
  • S-heteroatom containing alkyl substituted-3-oxo-pyrido?1,2-A!benzimidozole-4-carboxamide derivatives useful in treating central nervous system disorders
    Patent number: 5817668
    Abstract: A compound of the general formula 1; ##STR1## is disclosed as useful in treating disorders of the central nervous system. Pharmaceutical compositions and methods of treatment are also disclosed.
    Type: Grant
    Filed: October 3, 1997
    Date of Patent: October 6, 1998
    Assignee: Ortho Pharmaceutical Corporation
    Inventors: Allen B. Reitz, Alfonzo D. Jordan, Pauline J. Sanfilippo, Malcolm K. Scott, Anna Vavouyios-Smith