Patents by Inventor Alfonzo Jordan

Alfonzo Jordan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 1,3,8-Triazaspiro[4,5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders
    Publication number: 20060178390
    Abstract: The present invention is directed to novel 1,3,8-triazaspiro[4.5]decan-4-one derivatives of the general formula wherein all variables are as defined herein, useful in the treatment of disorders and conditions mediated by the ORL-1 G-protein coupled receptor. More particularly, the compounds of the present invention are useful in the treatment of disorders and conditions such as anxiety, depression, substance abuse, neuropathic pain, acute pain, migraine, asthma, cough and for improved cognition.
    Type: Application
    Filed: April 5, 2006
    Publication date: August 10, 2006
    Inventors: Alfonzo Jordan, Allen Reitz, Kevin Pan
  • 1,3,8-triazaspiro[4,5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders
    Patent number: 7053101
    Abstract: The present invention is directed to novel 1,3,8-triazaspiro[4.5]decan-4-one derivatives of the general formula wherein all variables are as defined herein, useful in the treatment of disorders and conditions mediated by the ORL-1 G-protein coupled receptor. More particularly, the compounds of the present invention are useful in the treatment of disorders and conditions such as anxiety, depression, substance abuse, neuropathic pain, acute pain, migraine, asthma, cough and for improved cognition.
    Type: Grant
    Filed: August 2, 2004
    Date of Patent: May 30, 2006
    Inventors: Alfonzo Jordan, Allen B. Reitz, Kevin Pan
  • Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE)
    Publication number: 20060079686
    Abstract: The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE.
    Type: Application
    Filed: August 4, 2005
    Publication date: April 13, 2006
    Inventors: Ellen Baxter, Robert Boyd, Steven Coats, Alfonzo Jordan, Allen Reitz, Charles Reynolds, Malcolm Scott
  • Novel 2-amino-quinazoline derivatives useful as inhibitors of beta-secretase (BACE)
    Publication number: 20060079687
    Abstract: The present invention is directed to novel 2-amino-3,4-dihydro-quinazoline derivatives, pharmaceutical compositions containing them and their use in the treatment of Alzheimer's disease (AD) and related disorders. The compounds of the invention are inhibitors of ?-secretase, also known as ?-site cleaving enzyme and BACE.
    Type: Application
    Filed: August 4, 2005
    Publication date: April 13, 2006
    Inventors: Ellen Baxter, Francois Bischoff, Robert Boyd, Mirielle Braeken, Steve Coats, Yifang Huang, Alfonzo Jordan, Chi Luo, Marc Mercken, Serge Maria Pieters, Allen Reitz, Charles Reynolds, Tina Ross, Brett Tounge, Mark Schulz, Hans De Winter
  • Neurotrophic pyrrolidines and piperidines, and related compositions and methods
    Publication number: 20050153951
    Abstract: This invention provides compounds having the following general structures: This invention also provides pharmaceutical compositions comprising same and methods of using these compositions to treat and prevent disorders characterized by neuronal damage.
    Type: Application
    Filed: September 14, 2004
    Publication date: July 14, 2005
    Inventors: Ramesh Kanojia, Alfonzo Jordan, Allen Reitz, Mark Macielag, Boyu Zhao
  • 1,2,8-Triazaspiro{decan-4-one derivatives useful for the treatment of orl-1receptor mediated disorders
    Publication number: 20050004154
    Abstract: The present invention is directed to novel 1,3,8-triazaspiro[4.5]decan-4-one derivatives of the general formula wherein all variables are as defined herein, useful in the treatment of disorders and conditions mediated by the ORL-1 G-protein coupled receptor. More particularly, the compounds of the present invention are useful in the treatment of disorders and conditions such as anxiety, depression, substance abuse, neuropathic pain, acute pain, migraine, asthma, cough and for improved cognition.
    Type: Application
    Filed: August 2, 2004
    Publication date: January 6, 2005
    Inventors: Alfonzo Jordan, Allen Reitz, Kevin Pan
  • 1,3,8-Triazaspiro[4.5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders
    Patent number: 6777421
    Abstract: The present invention is directed to novel 1,3,8-triazaspiro[4.5]decan-4-one derivatives of the general formula wherein all variables are as defined herein, useful in the treatment of disorders and conditions mediated by the ORL-1 G-protein coupled receptor. More particularly, the compounds of the present invention are useful in the treatment of disorders and conditions such as anxiety, depression, substance abuse, neuropathic pain, acute pain, migraine, asthma, cough and for improved cognition.
    Type: Grant
    Filed: April 5, 2002
    Date of Patent: August 17, 2004
    Assignee: Ortho-McNeil Pharmaceutical, Inc.
    Inventors: Alfonzo Jordan, Allen B. Reitz, Kevin Pan
  • 1,3,8-Triazaspiro[4.5]decan-4-one derivatives useful for the treatment of ORL-1 receptor mediated disorders
    Publication number: 20030109539
    Abstract: The present invention is directed to novel 1,3,8-triazaspiro[4.
    Type: Application
    Filed: April 5, 2002
    Publication date: June 12, 2003
    Inventors: Alfonzo Jordan, Allen B. Reitz, Kevin Pan