Patents by Inventor Alfred B. Bahnson

Alfred B. Bahnson has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Gene therapy for Gaucher disease using retroviral vectors
    Patent number: 5911983
    Abstract: The present invention relates to gene therapy for Gaucher disease using retroviral vectors which express the glucocerebrosidase gene. Methods are provided for transduction of autologous hematopoietic stem cells (e.g., human CD34+ cells) with these vectors and for transplantation of the transduced cells into a Gaucher disease patient to provide therapeutically effective levels of glucocerebrosidase activity. The invention also provides for retroviral vectors that express the glucocerebrosidase gene, and for human hematopoietic cells that contain the retroviral vector.
    Type: Grant
    Filed: June 6, 1995
    Date of Patent: June 15, 1999
    Assignee: University of Pittsburgh
    Inventors: John A. Barranger, Paul Robbins, Alfred B. Bahnson