Patents by Inventor Alfred I. Geller

Alfred I. Geller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Helper virus-free herpesvirus vector packaging system
    Patent number: 5998208
    Abstract: We have now discovered a helper virus free herpesvirus packaging system. This system can be used to package a wide range of desired nucleotide segments, preferably a DNA segment, into an empty herpesvirus particle because of the large genomes of herpesviruses. Preferably, the herpesvirus is an alpha herpesvirus. More preferably, the herpesvirus is an alpha herpesvirus such as Varicella-Zoster virus, pseudorabies virus, or a herpes simplex virus such as HSV-1 or HSV-2. Another preferred herpesvirus is Epstein-Barr virus.
    Type: Grant
    Filed: January 21, 1998
    Date of Patent: December 7, 1999
    Assignee: Children's Medical Center Corporation
    Inventors: Cornel Fraefel, Alfred I. Geller, Filip Lim
  • Helper virus-free herpesvirus vector packaging system
    Patent number: 5851826
    Abstract: We have now discovered a helper virus free herpesvirus packaging system. This system can be used to package a wide range of desired nucleotide segments, preferably a DNA segment, into an empty herpesvirus particle because of the large genomes of herpesviruses. Preferably, the herpesvirus is an alpha herpesvirus. More preferably, the herpesvirus is an alpha herpesvirus such as Varicella-Zoster virus, pseudorabies virus, or a herpes simplex virus such as HSV-1 or HSV-2. Another preferred herpesvirus is Epstein-Barr virus.
    Type: Grant
    Filed: July 26, 1995
    Date of Patent: December 22, 1998
    Assignee: Children's Medical Center Corporation
    Inventors: Cornel Fraefel, Alfred I. Geller, Filip Lim
  • Herpes simplex virus type I expression vector
    Patent number: 5501979
    Abstract: A recombinant HSV-1 vector capable of infecting and being propagated in a non-mitotic cell. The vector can be used to treat neurological diseases, and to produce animal and in vitro models of such diseases.
    Type: Grant
    Filed: November 30, 1993
    Date of Patent: March 26, 1996
    Assignee: The General Hospital Corporation
    Inventors: Alfred I. Geller, Xandra O. Breakefield