Patents by Inventor Alfred J. Nijkerk

Alfred J. Nijkerk has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 5320095
    Abstract: The invention relates to a device for use with the inhalation of powdered materials contained in rod-shaped capsules, having two parts (2, 3) which may be pivoted one relative to the other, and provided with a mixing chamber (7) having substantially tangentially directed air inlet openings, said mixing chamber having one end in communication with a mouth piece (6) and the other end in communication with a capsule receiving cavity (26), the latter being formed in conformity with the longitudinal sectional shape of a capsule and having at at least one longitudinal end a passage opening (27) for a transversely (=in the longitudinal direction of the capsule receiving cavity) reciprocating piercing needle, and wherein the part (2) of the device comprising the mouth piece (6) is mounted to pivot relative to the capsule receiving cavity comprising part (3) of the device between a closed ready for use-position and an opened position permitting the insertion of a capsule.
    Type: Grant
    Filed: September 23, 1992
    Date of Patent: June 14, 1994
    Assignee: Pharmachemie B.V.
    Inventors: Alfred J. Nijkerk, Jarig E. Schram, Sander J. Sinot
  • Patent number: 5177076
    Abstract: An aqueous folinate solution stable at refrigerator temperature is provided which contains folinate ions, complexed calcium ions, and if desired free calcium ions in a total amount of more than 12 mg/ml, as well as anions of a complexing agent for calcium. This solution is prepared by incorporating the complexing agent therein.
    Type: Grant
    Filed: November 21, 1989
    Date of Patent: January 5, 1993
    Assignee: Pharmachemie BV
    Inventors: Alfred J. Nijkerk, Johanna M. P. Vermeer
  • Patent number: 5104896
    Abstract: A carboplatin composition is provided in the form of an aqueous solution of carboplatin buffered at a pH of 2-6.5. Such a ready to use solution possesses a remarkable stability.
    Type: Grant
    Filed: May 29, 1990
    Date of Patent: April 14, 1992
    Assignee: Pharmachemie B.V.
    Inventors: Alfred J. Nijkerk, Johanna M. P. Vermeer