Patents by Inventor Alfred M. DelVecchio

Alfred M. DelVecchio has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hepatitis C virus NS5B truncated protein and methods thereof to identify antiviral compounds
    Publication number: 20030190606
    Abstract: The invention provides HCV NS5B polypeptides and DNA (RNA) encoding HCV NS5B polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing HCV NS5B polypeptides to screen for antiviral compounds.
    Type: Application
    Filed: January 13, 2003
    Publication date: October 9, 2003
    Applicant: SmithKline Beecham Corporation
    Inventor: Alfred M. DelVecchio
  • Hepatitis C virus NS5B truncated protein and methods thereof to identify antiviral compounds
    Patent number: 6228576
    Abstract: The invention provides HCV NS5B polypeptides and DNA (RNA) encoding HCV NS5B polypeptides and methods for producing such polypeptides by recombinant techniques. Also provided are methods for utilizing HCV NS5B polypeptides to screen for antiviral compounds.
    Type: Grant
    Filed: December 9, 1998
    Date of Patent: May 8, 2001
    Assignee: SmithKline Beecham Corporation
    Inventor: Alfred M. DelVecchio
  • Screening methods using an atpase protein from hepatitis C virus
    Patent number: 6010848
    Abstract: Disclosed are screening methods to identify molecules which activate or inhibit the activity of an ATPase protein of the Flaviviridae family, particularly NS4B protein of Hepatitis C Virus (HCV). These inhibitors and activators of HCV NS4B protein potentially can be used as antiviral compounds and as therapeutic agents for the treatment of viruses linked to the Flaviviridae family, particularly HCV, flaviviruses such as yellow fever virus, Dengue virus types 1-4, and pestiviruses such as bovine viral diarrhea virus and classic swine fever, among others.
    Type: Grant
    Filed: June 19, 1998
    Date of Patent: January 4, 2000
    Assignee: Smithkline Beecham Corporation
    Inventors: Alfred M. Delvecchio, Weidong Zhong