Patents by Inventor Alfred N. Fonteh

Alfred N. Fonteh has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for Evaluation and Treatment of Alzheimer's Disease and Applications Thereof
    Publication number: 20220236294
    Abstract: Methods to determine risk of Alzheimer's disease and applications thereof are described. Generally, systems and methods utilize analyte measurements, such as dicarboxylic acid levels, to determine a risk of Alzheimer's disease. Based on Alzheimer disease risk, diagnostics or treatments can be performed.
    Type: Application
    Filed: June 11, 2020
    Publication date: July 28, 2022
    Applicant: Huntington Medical Research Institutes
    Inventors: Alfred N. Fonteh, Michael G. Harrington, Katherine Jane Hamblin
  • METHODS OF DETERMINING LEVELS OF FREE AMINO ACIDS AND DIPEPTIDES AND DIAGNOSING ALZHEIMER'S DISEASE
    Publication number: 20150346219
    Abstract: Provided herein are methods of diagnosing Alzheimer's disease (“AD”) based on characteristic changes of the levels of certain free amino acids or dipeptides (collectively termed as “AD diagnosis markers”) in the body fluid sample of an individual, carnosine synthesis activities in the plasma, and dopamine synthesis activities in the plasma. Also provided are methods of simultaneously determining the levels of at least two free amino acids or dipeptides in the biological fluid sample of an individual.
    Type: Application
    Filed: June 2, 2015
    Publication date: December 3, 2015
    Inventors: Alfred N. FONTEH, Michael G. HARRINGTON
  • METHODS OF DETERMINING LEVELS OF FREE AMINO ACIDS AND DIPEPTIDES AND DIAGNOSING ALZHEIMER'S DISEASE
    Publication number: 20140308753
    Abstract: Provided herein are methods of diagnosing Alzheimer's disease (“AD”) based on characteristic changes of the levels of certain free amino acids or dipeptides (collectively termed as “AD diagnosis markers”) in the body fluid sample of an individual, carnosine synthesis activities in the plasma, and dopamine synthesis activities in the plasma. Also provided are methods of simultaneously determining the levels of at least two free amino acids or dipeptides in the biological fluid sample of an individual.
    Type: Application
    Filed: January 13, 2014
    Publication date: October 16, 2014
    Applicant: HUNTINGTON MEDICAL RESEARCH INSTITUTES
    Inventors: Alfred N. FONTEH, Michael G. HARRINGTON
  • Methods of determining levels of free amino acids and dipeptides and diagnosing Alzheimer's disease
    Patent number: 8670941
    Abstract: Provided herein are methods of diagnosing Alzheimer's disease (“AD”) based on characteristic changes of the levels of certain free amino acids or dipeptides (collectively termed as “AD diagnosis markers”) in the body fluid sample of an individual, carnosine synthesis activities in the plasma, and dopamine synthesis activities in the plasma. Also provided are methods of simultaneously determining the levels of at least two free amino acids or dipeptides in the biological fluid sample of an individual.
    Type: Grant
    Filed: August 17, 2007
    Date of Patent: March 11, 2014
    Assignee: Huntington Medical Research Institutes
    Inventors: Alfred N. Fonteh, Michael G. Harrington
  • METHODS OF DIAGNOSING AND TREATING MIGRAINE
    Publication number: 20120270816
    Abstract: The present invention provides methods of diagnosing migraine attacks and determining predisposition of an individual to the development of migraine based on sodium level in the cerebrospinal fluid (CSF) and/or brain extracellular fluid. The invention also provides methods of treating migraine, wherein the individual is selected for treatment based in the individual's sodium level in the CSF and/or brain extracellular fluid. The CSF sodium level may be based on the sodium concentration in the saliva.
    Type: Application
    Filed: March 6, 2012
    Publication date: October 25, 2012
    Inventors: Michael G. Harrington, Alfred N. Fonteh
  • Methods of diagnosing and treating migraine
    Patent number: 8163270
    Abstract: The present invention provides methods of diagnosing migraine attacks and determining predisposition of an individual to the development of migraine based on sodium level in the cerebrospinal fluid (CSF) and/or brain extracellular fluid. The invention also provides methods of treating migraine, wherein the individual is selected for treatment based in the individual's sodium level in the CSF and/or brain extracellular fluid. The CSF sodium level may be based on the sodium concentration in the saliva.
    Type: Grant
    Filed: April 24, 2007
    Date of Patent: April 24, 2012
    Assignee: Huntington Medical Research Institutes
    Inventors: Michael G. Harrington, Alfred N. Fonteh
  • METHODS OF DETERMINING LEVELS OF FREE AMINO ACID AND DIPEPTIDES AND DIAGNOSING ALZHEIMER'S DISEASES
    Publication number: 20110097736
    Abstract: Provided herein are methods of diagnosing Alzheimer's disease (“AD”) based on characteristic changes of the levels of certain free amino acids or dipeptides (collectively termed as “AD diagnosis markers”) in the body fluid sample of an individual, carnosine synthesis activities in the plasma, and dopamine synthesis activities in the plasma. Also provided are methods of simultaneously determining the levels of at least two free amino acids or dipeptides in the biological fluid sample of an individual.
    Type: Application
    Filed: August 17, 2007
    Publication date: April 28, 2011
    Inventors: Alfred N. Fonteh, Michael G. Harrington
  • METHODS OF DIAGNOSING AND TREATING MIGRAINE
    Publication number: 20090318374
    Abstract: The present invention provides methods of diagnosing migraine attacks and determining predisposition of an individual to the development of migraine based on sodium level in the cerebrospinal fluid (CSF) and/or brain extracellular fluid. The invention also provides methods of treating migraine, wherein the individual is selected for treatment based in the individual's sodium level in the CSF and/or brain extracellular fluid. The CSF sodium level may be based on the sodium concentration in the saliva.
    Type: Application
    Filed: April 24, 2007
    Publication date: December 24, 2009
    Inventors: Michael G. Harrington, Alfred N. Fonteh