Abstract: Provided herein are antibodies that bind to the alpha subunit of an IL-7 receptor (IL-7R?). Also provided are uses of these antibodies in therapeutic applications, such as treatment of inflammatory diseases. Further provided are cells that produce the antibodies, polynucleotides encoding the heavy and/or light chain regions of the antibodies, and vectors comprising the polynucleotides.

Abstract: The present invention relates to the use of a linear octafluorobutene as a dielectric compound in an environmentally safe dielectric-insulation or arc-extinction fluid for an apparatus for the generation, the transmission, the distribution and/or the usage of electrical energy.

Abstract: A method for operating an ore comminution circuit is provided. The method includes obtaining at least one sensor signal related to an ore feed to the comminution circuit; determining a first ore grindability parameter of the ore feed from the at least one sensor signal, using a model; determining a second ore grindability parameter using parameters of the comminution circuit and/or of at least one comminution device in the comminution circuit; and updating the model with the second ore grindability parameter and the at least one sensor signal.

Abstract: The present invention relates to an apparatus for the generation, the distribution and/or the usage of electrical energy. The apparatus comprises a housing enclosing an insulating space and an electrically conductive part arranged in the insulating space, said insulating space containing a dielectric insulation medium, at least a portion of which being in the form of an insulation gas comprising an organofluorine compound. According to the invention, at least some of the components of the apparatus that are directly exposed to the insulation gas are made of a material which remains unaltered during exposure to the insulation gas for a period of more than 1 year at operational conditions and/or have a surface, at least a portion of which is devoid of any nucleophilic group reactive towards the organofluorine compound and/or reactive towards any degradation product thereof at operational conditions.

Abstract: The present invention relates to an electrical apparatus having an insulating space which contains a dielectric insulation fluid comprising an organofluorine compound. At least one solid component of the apparatus that is directly exposed to the insulation fluid contains a basic body made of a first material and a protective layer made of a second material different from the first material, the protective layer being directly or indirectly applied on the basic body and having a thickness of at least 50 ?m. The organofluorine compound is selected from the group consisting of: fluoroethers, fluoroketones, fluoroolefins, fluoronitriles, and mixtures thereof, and the first material comprises or consists of a material selected from the group consisting of: a polymeric material, a ceramic, a composite material, and mixtures or combinations thereof.

Abstract: A method for operating an ore comminution circuit is provided. The method includes obtaining at least one sensor signal related to an ore feed to the comminution circuit; determining a first ore grindability parameter of the ore feed from the at least one sensor signal, using a model; determining a second ore grindability parameter using parameters of the comminution circuit and/or of at least one comminution device in the comminution circuit; and updating the model with the second ore grindability parameter and the at least one sensor signal.

Abstract: The application relates to a method for determining a property of a fluid component of a fluid present in a compartment of an electrical apparatus by means of a measurement device arranged outside the compartment and comprising a chamber for receiving a quantity of the fluid from the compartment. Amongst other steps of the method, an optical path in the chamber is illuminated by a light source and a first intensity of light is measured by a light detector. Then fluid is released from the compartment into the chamber and a second intensity (Ix) of light is measured. Based on these measurements the property of the fluid component is determined.

Abstract: The present invention relates to an electrical apparatus for generation, transmission, distribution and/or usage of electrical energy, comprising a housing enclosing an electrical apparatus interior space, at least a portion of which forms at least one insulation space having an electrical component and containing a surrounding insulation medium comprising an amount of carbon dioxide mco2. The insulation space is formed by at least one insulation space compartment, in which an adsorber for reducing or eliminating the amount of water mH2O and optionally further contaminants from the insulation medium is arranged. The amount of adsorber mads arranged in the at least one insulation space compartment complies with the formulae (I) and (II). m ads ? m H 2 ? O k ads , H 2 ? O ( I ) m ads ? 0.

Abstract: The present invention relates to the use of a linear octafluorobutene as a dielectric compound in an environmentally safe dielectric-insulation or arc-extinction fluid for an apparatus for the generation, the transmission, the distribution and/or the usage of electrical energy.

Abstract: A method and device for estimating a density value ?m indicative of a true density ? or for estimating a viscosity value ?m indicative of a true viscosity ? of a fluid is disclosed. For this, a first resonance frequency fR of a first mechanical oscillator in a reference volume and a second resonance frequency fF of a second mechanical oscillator in contact with the fluid are measured. The estimated value ?m or ?m is then derived using these resonance frequencies fR and fF. During this derivation, at least one fluid-temperature- or fluid-pressure-dependent parameter of the fluid is used. Additionally or alternatively, the first (i.e. reference) mechanical oscillator is arranged in contact with a reference fluid. Thus, fundamental errors in the derivation of the estimated value ?m or ?m are reduced and the estimated value becomes more reliable.

Abstract: A method for deriving at least one operating parameter of a fluid-insulated electrical apparatus, in particular of gas-insulated switchgear. The operating parameter is dependent on a dielectric breakdown strength of an insulation fluid of the electrical apparatus. The insulation fluid includes at least three components that are assigned to at least a first and a second component group such that at least one component group comprises at least two components. The component groups differ in their weighted average values of the molecular masses of the components in the respective component groups. At least one quantity which is indicative of the concentration of the first component group and of the concentration of the second component group is determined from the insulation fluid, e.g. by measuring one or more measurement variables with one or more sensors. The operating parameter is then derived using the at least one quantity.

Abstract: The application relates to a method for determining a property of a fluid component of a fluid present in a compartment of an electrical apparatus by means of a measurement device arranged outside the compartment and comprising a chamber for receiving a quantity of the fluid from the compartment. Amongst other steps of the method, an optical path in the chamber is illuminated by a light source and a first intensity of light is measured by a light detector. Then fluid is released from the compartment into the chamber and a second intensity (Ix) of light is measured. Based on these measurements the property of the fluid component is determined.

Abstract: The present invention relates to an electrical apparatus having an insulating space which contains a dielectric insulation fluid comprising an organofluorine compound. At least one solid component of the apparatus that is directly exposed to the insulation fluid contains a basic body made of a first material and a protective layer made of a second material different from the first material, the protective layer being directly or indirectly applied on the basic body and having a thickness of at least 50 ?m. The organofluorine compound is selected from the group consisting of: fluoroethers, fluoroketones, fluoroolefins, fluoronitriles, and mixtures thereof, and the first material comprises or consists of a material selected from the group consisting of: a polymeric material, a ceramic, a composite material, and mixtures or combinations thereof.

Abstract: An apparatus for the generation, the distribution or the usage of electrical energy, the apparatus including a housing enclosing an insulating space and an electrical component arranged in the insulating space. The insulating space contains a dielectric insulation gas including an organofluorine compound A. The apparatus further includes a molecular sieve arranged such as to come into contact with the insulation gas. The molecular sieve has an average pore size y greater than the molecular size of at least one decomposition product of the organofluorine compound A generated during operation of the apparatus. The adsorption capability of the molecular sieve for organofluorine compound A is lower than for the at least one decomposition product. The apparatus further includes at least one desiccant arranged such as to come into contact with the insulation gas.

Abstract: A monitoring device for determining the concentration of a dielectric insulation fluid such as a perfluoroketones in a room housing at least one high-voltage electrical apparatus and being accessible by humans essentially without modifying the room conditions, for example the room being a part of an air-insulated substation, with the monitoring system including one or more sensors for determining an emission and/or absorption of the dielectric insulation fluid molecules at at least one wavelength or wavelength band of the electromagnetic wave spectrum.

Abstract: The present invention relates to an electrical apparatus for generation, transmission, distribution and/or usage of electrical energy, comprising a housing enclosing an electrical apparatus interior space, at least a portion of which forms at least one insulation space having an electrical component and containing a surrounding insulation medium comprising an amount of carbon dioxide mco2. The insulation space is formed by at least one insulation space compartment, in which an adsorber for reducing or eliminating the amount of water mH2O and optionally further contaminants from the insulation medium is arranged. The amount of adsorber mads arranged in the at least one insulation space compartment complies with the formulae (I) and (II). m ads ? m H 2 ? O k ads , H 2 ? O ( I ) m ads ? 0.

Abstract: The present invention relates to an apparatus for the generation, the distribution and/or the usage of electrical energy. The apparatus comprises a housing enclosing an insulating space and an electrically conductive part arranged in the insulating space, said insulating space containing a dielectric insulation medium, at least a portion of which being in the form of an insulation gas comprising an organofluorine compound. According to the invention, at least some of the components of the apparatus that are directly exposed to the insulation gas are made of a material which remains unaltered during exposure to the insulation gas for a period of more than 1 year at operational conditions and/or have a surface, at least a portion of which is devoid of any nucleophilic group reactive towards the organofluorine compound and/or reactive towards any degradation product thereof at operational conditions.

Abstract: A method and device for operating a fluid-insulated electrical apparatus. The insulation fluid of the electrical apparatus includes at least two components. The method includes the step of determining a physical state of the insulation fluid by measuring at least three measurement variables with sensors. The method further includes the step of deriving trend variables indicative of changes over time for the measurement variables and/or for characterizing variables. These characterizing variables are derived from the measurement variables by using a relating equation, such as an equation of state, and are also indicative of the physical state of the insulation fluid. By testing for specific patterns of the trend variables, an operating state of the electrical apparatus is determined. The possible operating states correspond to specific and distinguishable non-fault and fault scenarios for the electrical apparatus.

Abstract: A process for providing a contamination-reducing component to an electrical apparatus, the electrical apparatus including a housing enclosing an insulating space and an electrical component arranged in the insulating space, the insulating space including an insulation medium which includes or consists of carbon dioxide. The process includes the steps of presaturating the contamination-reducing component with carbon dioxide before placing it inside the electrical apparatus.

Abstract: A dielectric insulation medium including sulphur hexafluoride (SF6) and/or tetrafluoro methane (CF4), in a mixture with at least one further component being an at least partially fluorinated fluoroketone.