Abstract: The object of the invention is therefore to provide a method for the preparation of amino-functional polyorganosiloxanes, in which (A) organosiloxanes containing Si—OH groups are reacted with (B) at least stoichiometric amounts of monoalkoxy(aminoalkyl) silanes with respect to the Si—OH groups, wherein catalytically active additives selected from acid, base or metal-organic compound are used in amounts of less than 0.1 ppm acid, less than 30 ppm base and less than 0.4% metal-organic compound.

Abstract: Organopolysiloxanes having amino groups are prepared by reacting wherein (A) silanes of the formula R1—O—SiR2—O—R1 ??(I) with (B) silanes of the formula (R32N)—X—SiR42—O—R2 ??(II) and (C) water.

Abstract: The object of the invention is therefore to provide a method for the preparation of amino-functional polyorganosiloxanes, in which (A) organosiloxanes containing Si—OH groups are reacted with (B) at least stoichiometric amounts of monoalkoxy(aminoalkyl) silanes with respect to the Si—OH groups, wherein catalytically active additives selected from acid, base or metal-organic compound are used in amounts of less than 0.1 ppm acid, less than 30 ppm base and less than 0.4% metal-organic compound.

Abstract: Organopolysiloxanes containing units of the formulae O3-a/2RaSi—Y—(SiRaO3-a/2)b and R1cSiO4-c are prepared by catalyzed reaction, in a first step, of a mixture of X3-aRaSi—Y—(SiRaX3-a)b and R1cSiX4-c and siloxanes which have structural units of the formulae O3-a/2RaSi—Y—(SiRaO3-a/2)b and R1cSiO4-c and having weight average molar mass of 100 to 950 g/mol and reacting the mixture obtained therefrom with water or aqueous acid, producing organopolysiloxanes having a weight average molar mass of 1,000 to 100,000 g/mol, wherein R and R1 each are monovalent C1-30 SiC-bonded organic groups optionally containing one or more N and/or O atoms, Y is a 2-12 valent C1-30 organic group optionally containing one or more O atoms, X is a hydrolyzable group, a is 0 or 1, b is 1 to 11, and c is 0, 1, 2, or 3.

Abstract: Organopolysiloxanes containing units of the formulae O3-a/2RaSi—Y—(SiRaO3-a/2)b and R1cSiO4-c are prepared by catalyzed reaction, in a first step, of a mixture of X3-aRaSi—Y—(SiRaX3-a)b and R1cSiX4-c and siloxanes which have structural units of the formulae O3-a/2RaSi—Y—(SiRaO3-a/2)b and R1cSiO4-c and having weight average molar mass of 100 to 950 g/mol and reacting the mixture obtained therefrom with water or aqueous acid, producing organopolysiloxanes having a weight average molar mass of 1,000 to 100,000 g/mol, wherein R and R1 each are monovalent C1-30 SiC-bonded organic groups optionally containing one or more N and/or O atoms, Y is a 2-12 valent C1-30 organic group optionally containing one or more O atoms, X is a hydrolyzable group, a is 0 or 1, b is 1 to 11, and c is 0, 1, 2, or 3.

Abstract: Cyclic siloxanes are separated from short chain hydroxyl-terminated siloxanes by contact with steam at at least 650 hPa absolute. The cyclic siloxanes and other components which are separated by use of steam can be recovered by phase separation, and preferably used in other processes.

Abstract: Cyclic siloxanes are separated from short chain hydroxyl-terminated siloxanes by contact with steam at at least 650 hPa absolute. The cyclic siloxanes and other components which are separated by use of steam can be recovered by phase separation, and preferably used in other processes.

Abstract: The selectivity of hydrosilylation of unsaturated organic compounds by Si—H functional organosilicon compounds is improved by use of a silyl polyphosphate ester in conjunction with a platinum hydrosilylation catalyst.

Abstract: The invention relates to a method for producing alkoxy-substituted 1,2-bissilylethanes of the general formula 1 (R1O)nR2(3-n)Si—CH2—CH2—SiR2(3-n)(OR1)n??(1), which comprises reacting, in a first step, a mixture containing compounds of the general formulae 2 and 3 ClnR2(3-n)Si—CH2—CH2—SiR2(3-n)Cln??(2) ClnR2(3-n)Si—CH?CH—SiR2(3-n)Cln??(3) with an alcohol of the general formula 4 R1OH??(4) and, in a second step, subjecting the resultant mixture which contains compounds of the general formula 1 and compounds of the general formula 5 (R1O)nR2(3-n)Si—CH?CH—SiR2(3-n)(OR1)n??(5) to reductive conditions such that the compound of the general formula 5 is converted into a compound of the general formula 1, wherein R1 and R2 are monovalent, unsubstituted or halogen-substituted hydrocarbon radicals having 1 to 16 carbon atoms and n is the value 1, 2 or 3.

Abstract: Alkoxysilylmethyl isocyanurates are prepared in high space time yield by reaction of a chloromethylalkoxysilane with a metal isocyanate in the presence of a tetrakis[hydrocarbon]ammonium phase transfer catalyst, with minimal formation of byproducts.

Abstract: Blocked silyl isocyanates contain a methylene group between the blocked isocyanate group and silicon. The blocked isocyanates are easily prepared in high yield and purity.

Abstract: Blocked silyl isocyanates contain a methylene group between the blocked isocyanate group and silicon. The blocked isocyanates are easily prepared in high yield and purity.

Abstract: A new class of C2-symmetric biaryldiphosphines comprising a fused ring system (dioxacycle) which has at least seven ring atoms and can be varied synthetically. The biaryldiphosphines can be used as ligands for preparing metal complexes useful as catalysts in organic synthesis, and the dioxacycles can be varied to optimize reaction with specific substrates.

Abstract: A process is provided for preparing an enantiopure 1,3-dioxolan-4-one or 1,3-oxathiolan-5-one derivative, which includes bringing a mixture containing enantiomeric 1,3-dioxolan-4-one or 1,3-oxathiolan-5-one derivatives and an enzyme with hydrolytic activity into contact in the presence of a nucleophile. Cleaving a dioxolanone/oxathiolanone ring of one enantiomer occurs by the enzyme with hydrolytic activity and, after the cleavage of one enantiomer has taken place, the uncleaved enantiomer of the 1,3-dioxolan-4-one or 1,3-oxathiolan-5-one derivative is isolated.

Abstract: Process for the enantioselective preparation of secondary alcohols, wherein a racemic or enantiomerically enriched mixture of acetoacetic esters of chiral secondary alcohols is subjected to enantioselective enzymatic solvolysis in the presence of a nucleophile and a lipase capable of the solvolytic cleavage of an ester group.

Abstract: The invention relates to tyrosine kinase inhibitors of the bis-indolyl compound type of the general formula I: pharmaceuticals containing them and their use for the treatment of malignant and other diseases based on pathological cell proliferation.

Abstract: A process is provided for preparing an enantiopure 1,3-dioxolan-4-one or 1,3-oxathiolan-5-one derivative, which includes bringing a mixture containing enantiomeric 1,3-dioxolan-4-one or 1,3-oxathiolan-5-one derivatives and an enzyme with hydrolytic activity into contact in the presence of a nucleophile. Cleaving a dioxolanone/oxathiolanone ring of one enantiomer occurs by the enzyme with hydrolytic activity and, after the cleavage of one enantiomer has taken place, the uncleaved enantiomer of the 1,3-dioxolan-4-one or 1,3-oxathiolan-5-one derivative is isolated.

Abstract: A process for the preparation of an enantiomerically pure tertiary &bgr;-hydroxycarboxylic acid or its ester, wherein an enantiomer mixture of compounds is brought into contact with an enzyme, which is capable of the hydrolytic cleavage of an ester bond, in an aqueous medium such that one enantiomer of the enantiomer mixture is hydrolyzed.

Abstract: The invention relates to tyrosine kinase inhibitors of the bis-indolyl compound type of the general formula I: 1

Abstract: The invention relates to tyrosine kinase inhibitors of the bis-indolyl compound type of the general formula I: pharmaceuticals containing them and their use for the treatment of malignant and other diseases based on pathological cell proliferation.