Patents by Inventor Alfred R. Sundquist

Alfred R. Sundquist has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compositions and methods for inhibiting light-induced inactivation of biological reagents
    Patent number: 7588908
    Abstract: Disclosed is a fluorescent conjugate comprising a biological reagent, a fluorescent molecule, and a means for impeding phototoxic degradation of the biological reagent. The impeding means can be a cross-linking substance having a long molecular distance, whereby the cross-linking substance links the fluorescent molecule and the biological reagent; a quencher of singlet oxygen; a quencher of a free radical; or a combination thereof. Also disclosed is a solution comprising a fluorescent conjugate of a biological reagent and a fluorescent molecule together with an oxygen depleting system.
    Type: Grant
    Filed: January 7, 2003
    Date of Patent: September 15, 2009
    Assignee: Biosite, Inc.
    Inventors: Kenneth F. Buechler, Paul H. McPherson, Alfred R. Sundquist
  • Novel compositions and methods for inhibiting light-induced inactivation of biological reagents
    Publication number: 20030129642
    Abstract: Disclosed is a fluorescent conjugate comprising a biological reagent, a fluorescent molecule, and a means for impeding phototoxic degradation of the biological reagent. The impeding means can be a cross-linking substance having a long molecular distance, whereby the cross-linking substance links the fluorescent molecule and the biological reagent; a quencher of singlet oxygen; a quencher of a free radical; or a combination thereof. Also disclosed is a solution comprising a fluorescent conjugate of a biological reagent and a fluorescent molecule together with an oxygen depleting system.
    Type: Application
    Filed: January 7, 2003
    Publication date: July 10, 2003
    Applicant: Biosite Diagnostics, Inc.
    Inventors: Kenneth F. Buechler, Paul H. McPherson, Alfred R. Sundquist
  • Compositions and methods for inhibiting light-induced inactivation of biological reagents
    Patent number: 6544797
    Abstract: Disclosed is a fluorescent conjugate comprising a biological reagent, a fluorescent molecule, and a means for impeding phototoxic degradation of the biological reagent. The impeding means can be a cross-linking substance having a long molecular distance, whereby the cross-linking substance links the fluorescent molecule and the biological reagent; a quencher of singlet oxygen; a quencher of a free radical; or a combination thereof. Also disclosed is a solution comprising a fluorescent conjugate of a biological reagent and a fluorescent molecule together with an oxygen depleting system.
    Type: Grant
    Filed: April 9, 1997
    Date of Patent: April 8, 2003
    Assignee: Biosite Diagnostics, Inc.
    Inventors: Kenneth F. Buechler, Paul H. McPherson, Alfred R. Sundquist
  • Methods, procedures, and formats for using microelectronic array devices to perform multiplex immunoassay analyses
    Publication number: 20010049111
    Abstract: This invention relates to devices and methods for carrying out multi-step and multiplex immunoaffinity binding reactions in microscopic formats. In particular, these devices and methods allow the user to rapidly carry out multiple immunoassays in the same sample volume, and to rapidly resolve the results of those immunoassays in an electronically assisted format. The assays may be further multiplexed in that several samples may be analyzed and visualized on the same microelectronic array.
    Type: Application
    Filed: February 14, 2001
    Publication date: December 6, 2001
    Inventors: Norbert Windhab, Michael J. Heller, Richard R. Anderson, Michael D. Fiechtner, Tina S. Nova, Markus Schweitzer, Alfred R. Sundquist, Christoph Brucher, Jill M. Orwick, Jochen Muller, Stefan Raddatz, Donald E. Ackley, Christian Hamon