Patents by Inventor Alfred Sui-Ting Lui

Alfred Sui-Ting Lui has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heterocyclic antiviral compounds
    Patent number: 8232271
    Abstract: Compounds having the formula I wherein R1, R2, R3a, R3b, R3c, R4, R5 and p are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
    Type: Grant
    Filed: October 30, 2009
    Date of Patent: July 31, 2012
    Assignee: Roche Palo Alto LLC
    Inventors: Jim Li, Alfred Sui-Ting Lui, Kristen Lynn McCaleb, Francisco Xavier Talamas
  • Heterocyclic antiviral compounds
    Patent number: 8168792
    Abstract: Compounds having the formula A-R wherein A is a heteroaryl and R is Ia, Ib or Ic and wherein A, R, R1, R2a, R2b, R2c, R3a, R3b, R4, R5, R6, Ra, Rb, Rc, Rd, X, X1, X2 and n are as are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
    Type: Grant
    Filed: March 5, 2010
    Date of Patent: May 1, 2012
    Assignee: Roche Palo Alto LLC
    Inventors: Sarah C. Abbot, Alfred Sui-Ting Lui, Jim Li, Francisco Xavier Talamas
  • Heterocyclic antiviral compounds
    Patent number: 8158631
    Abstract: Compounds having the formula I wherein R1, R2, R3, R4, and R5 are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
    Type: Grant
    Filed: June 24, 2010
    Date of Patent: April 17, 2012
    Assignee: Roche Palo Alto LLC
    Inventors: Elbert Chin, Javier de Vicente Fidalgo, Jim Li, Alfred Sui-Ting Lui, Kristen Lynn McCaleb, Ryan Craig Schoenfeld, Francisco Xavier Talamas
  • HETEROCYCLIC ANTIVIRAL COMPOUNDS
    Publication number: 20100330032
    Abstract: Compounds having the formula I wherein R1, R2, R3, R4, and R5 are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
    Type: Application
    Filed: June 24, 2010
    Publication date: December 30, 2010
    Inventors: Elbert Chin, Javier de Vicente Fidalgo, Jim Li, Alfred Sui-Ting Lui, Kristen Lynn McCaleb, Ryan Craig Schoenfeld, Francisco Xavier Talamas
  • HETEROCYCLIC ANTIVIRAL COMPOUNDS
    Publication number: 20100226879
    Abstract: Compounds having the formula A-R wherein A is a hetereoaryl and R is Ia, Ib or Ic and wherein A, R, R1, R2a, R2b, R2c, R3a, R3b, R4, R5, R6, Ra, Rb, Rc, Rd, X, X1, X2 and n are as are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
    Type: Application
    Filed: March 5, 2010
    Publication date: September 9, 2010
    Inventors: Sarah C. Abbot, Alfred Sui-Ting Lui, Jim Li, Francisco Xavier Talamas
  • Diaminopyrimidines as P2Xand P2Xmodulators
    Patent number: 7776872
    Abstract: Compounds of the formula I: or pharmaceutically acceptable salts thereof, wherein A, D, E, G, J, X, Y, Z R6, R7 and R8 are as defined herein. Also provided are methods of using the compounds for treating diseases mediated by a P2X3 and/or a P2X2/3 receptor antagonist and methods of making the compounds.
    Type: Grant
    Filed: August 25, 2006
    Date of Patent: August 17, 2010
    Assignee: Roche Palo Alto LLC
    Inventors: Michael Patrick Dillon, Alam Jahangir, Alfred Sui-Ting Lui, Robert Stephen Wilhelm
  • HETEROCYCLIC ANTIVIRAL COMPOUNDS
    Publication number: 20100111900
    Abstract: Compounds having the formula I wherein R1, R2, R3a, R3b, R3c, R4, R5 and p are as defined herein are Hepatitis C virus NS5b polymerase inhibitors. Also disclosed are compositions and methods for treating an HCV infection and inhibiting HCV replication.
    Type: Application
    Filed: October 30, 2009
    Publication date: May 6, 2010
    Inventors: Jim Li, Alfred Sui-Ting Lui, Kristen Lynn McCaleb, Francisco Xavier Talamas
  • Imidazo-substituted compounds as p38 kinase inhibitors
    Patent number: 7285561
    Abstract: The present invention discloses compounds corresponding to formula I: wherein A, Z, Z1, Y, R1 and R2 are as defined in the specification, as well as pharmaceutical formulations, methods of making and uses thereof.
    Type: Grant
    Filed: July 13, 2006
    Date of Patent: October 23, 2007
    Assignee: Roche Palo Alto LLC
    Inventors: David Michael Goldstein, Ronald Charles Hawley, Alfred Sui-Ting Lui, Eric Brian Sjogren
  • Imidazo-substituted compounds as p38 kinase inhibitors
    Patent number: 7285559
    Abstract: The present invention discloses compounds corresponding to formula I: wherein A, Z, Z1, Y, R1 and R2 are as defined in the specification, as well as pharmaceutical formulations, methods of making and uses thereof.
    Type: Grant
    Filed: July 13, 2006
    Date of Patent: October 23, 2007
    Assignee: Roche Palo Alto LLC
    Inventors: David Michael Goldstein, Ronald Charles Hawley, Alfred Sui-Ting Lui, Eric Brian Sjogren
  • Imidazo-substituted compounds as p38 kinase inhibitors
    Patent number: 7081462
    Abstract: The present invention discloses compounds corresponding to formula I: wherein A, Z, Z1, Y, R1 and R2 are as defined in the specification, as well as pharmaceutical formulations, methods of making and uses thereof.
    Type: Grant
    Filed: May 4, 2005
    Date of Patent: July 25, 2006
    Assignee: Roche Palo Alto LLC
    Inventors: David Michael Goldstein, Ronald Charles Hawley, Alfred Sui-Ting Lui, Eric Brian Sjogren
  • Imidazo-substituted compounds as p38 kinase inhibitors
    Patent number: 6949560
    Abstract: The present invention discloses compounds corresponding to formula I: wherein A, Z, Z1, Y, R1 and R2 are as defined in the specification, as well as pharmaceutical formulations, methods of making and uses thereof.
    Type: Grant
    Filed: April 3, 2003
    Date of Patent: September 27, 2005
    Assignee: Roche Palo Alto LLC
    Inventors: David Michael Goldstein, Ronald Charles Hawley, Alfred Sui-Ting Lui, Eric Brian Sjogren
  • Imidazo-substituted compounds as p38 kinase inhibitors
    Publication number: 20030232847
    Abstract: The present invention discloses compounds corresponding to formula I: 1
    Type: Application
    Filed: April 3, 2003
    Publication date: December 18, 2003
    Inventors: David Michael Goldstein, Ronald Charles Hawley, Alfred Sui-Ting Lui, Eric Brian Sjogren