Abstract: A liquid supply system in which liquid is only supposed to flow from a high-pressure upstream portion to a low-pressure downstream portion is provided with a backflow preventer and upstream thereof with an isolating valve assembly. The backflow preventer opens completely whenever the pressure upstream of itself drops below a predetermined minimum, thereby draining the conduit downstream of itself to prevent reverse flow in the line. The isolating valve assembly continuously monitors the pressure in the upstream and downstream conduit portions and shuts a cutoff valve between these portions whenever the pressure differential between the two portions falls below a predetermined minimum, while simultaneously depressurizing or draining the downstream portion.