Patents by Inventor Alfredo Andres Celedon
Alfredo Andres Celedon has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Patent number: 11860354Abstract: An imaging system is described for measuring the position or movement of a particle having a size of less than about 20 microns. The system comprises an optional sample holder configured to hold a sample with a particle, an optional illumination source configured to illuminate the sample, a lens having a magnification ratio from about 1:5 to about 5:1 and configured to generate the image of the sample, an image sensor having a pixel size of up to about 20 microns and configured to sense the image of the sample, and an image processor operatively connected to the image sensor to process the image of the particle in order to determine the position or movement of the particle. The dimension of the image of each particle is at least about 1.5 times the dimension of the particle multiplied by the magnification ratio of the lens, and the image of each particle is distributed on at least two pixels of the sensor. The imaged area of the sample is at least about one millimeter squared.Type: GrantFiled: May 12, 2022Date of Patent: January 2, 2024Assignee: Scanogen Inc.Inventors: Zhiguang Xu, Alfredo Andres Celedon
-
Publication number: 20230039492Abstract: The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the complex comprises an elongated region, a particle that is coupled to the first probe, and a solid support that is coupled to the second probe. Specific binding of a target analyte can be distinguished from non-specific binding of the particle by measuring the displacement of the particle.Type: ApplicationFiled: October 25, 2022Publication date: February 9, 2023Inventors: Alfredo Andres Celedon, Saravana Radha Krishna Murthy, Zhiguang Xu, Danielle Elise Schultz, Troy Allen Horn
-
Patent number: 11505818Abstract: The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the complex comprises an elongated region, a particle that is coupled to the first probe, and a solid support that is coupled to the second probe. Specific binding of a target analyte can be distinguished from non-specific binding of the particle by measuring the displacement of the particle.Type: GrantFiled: December 12, 2018Date of Patent: November 22, 2022Assignee: Scanogen Inc.Inventors: Alfredo Andres Celedon, Saravana Radha Krishna Murthy, Zhiguang Xu, Danielle Elise Schultz, Troy Allen Horn
-
Publication number: 20220276480Abstract: An imaging system is described for measuring the position or movement of a particle having a size of less than about 20 microns. The system comprises an optional sample holder configured to hold a sample with a particle, an optional illumination source configured to illuminate the sample, a lens having a magnification ratio from about 1:5 to about 5:1 and configured to generate the image of the sample, an image sensor having a pixel size of up to about 20 microns and configured to sense the image of the sample, and an image processor operatively connected to the image sensor to process the image of the particle in order to determine the position or movement of the particle. The dimension of the image of each particle is at least about 1.5 times the dimension of the particle multiplied by the magnification ratio of the lens, and the image of each particle is distributed on at least two pixels of the sensor. The imaged area of the sample is at least about one millimeter squared.Type: ApplicationFiled: May 12, 2022Publication date: September 1, 2022Inventors: ZHIGUANG XU, ALFREDO ANDRES CELEDON
-
Patent number: 11360296Abstract: An imaging system is described for measuring the position or movement of a particle having a size of less than about 20 microns. The system comprises an optional sample holder configured to hold a sample with a particle, an optional illumination source configured to illuminate the sample, a lens having a magnification ratio from about 1:5 to about 5:1 and configured to generate the image of the sample, an image sensor having a pixel size of up to about 20 microns and configured to sense the image of the sample, and an image processor operatively connected to the image sensor to process the image of the particle in order to determine the position or movement of the particle. The dimension of the image of each particle is at least about 1.5 times the dimension of the particle multiplied by the magnification ratio of the lens, and the image of each particle is distributed on at least two pixels of the sensor. The imaged area of the sample is at least about one millimeter squared.Type: GrantFiled: September 4, 2020Date of Patent: June 14, 2022Assignee: Scanogen IncInventors: Zhiguang Xu, Alfredo Andres Celedon
-
Publication number: 20200400932Abstract: An imaging system is described for measuring the position or movement of a particle having a size of less than about 20 microns. The system comprises an optional sample holder configured to hold a sample with a particle, an optional illumination source configured to illuminate the sample, a lens having a magnification ratio from about 1:5 to about 5:1 and configured to generate the image of the sample, an image sensor having a pixel size of up to about 20 microns and configured to sense the image of the sample, and an image processor operatively connected to the image sensor to process the image of the particle in order to determine the position or movement of the particle. The dimension of the image of each particle is at least about 1.5 times the dimension of the particle multiplied by the magnification ratio of the lens, and the image of each particle is distributed on at least two pixels of the sensor. The imaged area of the sample is at least about one millimeter squared.Type: ApplicationFiled: September 4, 2020Publication date: December 24, 2020Inventors: ZHIGUANG XU, ALFREDO ANDRES CELEDON
-
Patent number: 10768406Abstract: An imaging system is described for measuring the position or movement of a particle having a size of less than about 20 microns. The system comprises an optional sample holder configured to hold a sample with a particle, an optional illumination source configured to illuminate the sample, a lens having a magnification ratio from about 1:5 to about 5:1 and configured to generate the image of the sample, an image sensor having a pixel size of up to about 20 microns and configured to sense the image of the sample, and an image processor operatively connected to the image sensor to process the image of the particle in order to determine the position or movement of the particle. The dimension of the image of each particle is at least about 1.5 times the dimension of the particle multiplied by the magnification ratio of the lens, and the image of each particle is distributed on at least two pixels of the sensor. The imaged area of the sample is at least about one millimeter squared.Type: GrantFiled: February 28, 2017Date of Patent: September 8, 2020Assignee: Scanogen Inc.Inventors: Zhiguang Xu, Alfredo Andres Celedon
-
Publication number: 20190112641Abstract: The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the complex comprises an elongated region, a particle that is coupled to the first probe, and a solid support that is coupled to the second probe. Specific binding of a target analyte can be distinguished from non-specific binding of the particle by measuring the displacement of the particle.Type: ApplicationFiled: December 12, 2018Publication date: April 18, 2019Applicant: Scanogen Inc.Inventors: Alfredo Andres Celedon, Saravana Radha Krishna Murthy, Zhiguang Xu, Danielle Elise Schultz, Troy Allen Horn
-
Patent number: 10179930Abstract: The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the complex comprises an elongated region, a particle that is coupled to the first probe, and a solid support that is coupled to the second probe. Specific binding of a target analyte can be distinguished from non-specific binding of the particle by measuring the displacement of the particle.Type: GrantFiled: February 5, 2015Date of Patent: January 15, 2019Assignee: Scanogen Inc.Inventors: Alfredo Andres Celedon, Saravana Radha Krishna Murthy, Zhiguang Xu, Danielle Elise Schultz, Troy Allen Horn
-
Publication number: 20170363851Abstract: An imaging system is described for measuring the position or movement of a particle having a size of less than about 20 microns. The system comprises an optional sample holder configured to hold a sample with a particle, an optional illumination source configured to illuminate the sample, a lens having a magnification ratio from about 1:5 to about 5:1 and configured to generate the image of the sample, an image sensor having a pixel size of up to about 20 microns and configured to sense the image of the sample, and an image processor operatively connected to the image sensor to process the image of the particle in order to determine the position or movement of the particle. The dimension of the image of each particle is at least about 1.5 times the dimension of the particle multiplied by the magnification ratio of the lens, and the image of each particle is distributed on at least two pixels of the sensor. The imaged area of the sample is at least about one millimeter squared.Type: ApplicationFiled: February 28, 2017Publication date: December 21, 2017Inventors: Zhiguang Xu, Alfredo Andres Celedon
-
Publication number: 20160258003Abstract: The present application relates to detection units and methods for detecting one or more target analytes in a sample using a complex formed by a target and first and second probes, wherein the complex comprises an elongated region, a particle that is coupled to the first probe, and a solid support that is coupled to the second probe. Specific binding of a target analyte can be distinguished from non-specific binding of the particle by measuring the displacement of the particle.Type: ApplicationFiled: February 5, 2015Publication date: September 8, 2016Applicant: Scanogen Inc.Inventors: Alfredo Andres Celedon, Saravana Radha Krishna Murthy, Zhiguang Xu, Danielle Elise Schultz, Troy Allen Horn
-
Patent number: 9382578Abstract: The present application relates to detection units and methods for detecting one or more target analytes in a sample. In certain embodiments, the detection unit provides a first and second surface connected by a filament which is capable of binding the target analyte in the sample. In other embodiments, the detection unit provides a circular molecule capable of binding the target analyte and accumulating torsional stress in the presence of a twisting agent. The methods provide for the detection of the target analyte through the generation of a detectable signal following the binding of the target analyte to the filament.Type: GrantFiled: September 24, 2013Date of Patent: July 5, 2016Assignee: Scanogen Inc.Inventor: Alfredo Andres Celedon
-
Patent number: 9382580Abstract: Detection units and methods for detecting one or more target analytes in a sample are disclosed. The detection unit provides a first and second surface connected by a filament which is capable of binding the target analyte in the sample. The methods provide for the detection of the target analyte through the generation of a detectable signal following the binding of the target analyte to the filament.Type: GrantFiled: October 10, 2012Date of Patent: July 5, 2016Assignee: Scanogen Inc.Inventor: Alfredo Andres Celedon
-
Publication number: 20150307926Abstract: The present application relates to detection units and methods for detecting one or more target analytes in a sample. The detection unit provides a first and second surface connected by a filament which is capable of binding the target analyte in the sample. Double-stranded DNA molecules are provided having a continuous strand and a discontinuous strand, and an active segment that is designed to hybridize to a target nucleic acid of interest, where the continuous strand has between 0 and 100 unpaired nucleotides in the active segment and the discontinuous strand has between 5 and 100 unpaired nucleotides at its 3? end and/or its 5? end. The unpaired nucleotides in the continuous strand can form a secondary structure, such as a loop.Type: ApplicationFiled: April 21, 2015Publication date: October 29, 2015Inventor: Alfredo Andres Celedon
-
Publication number: 20140274795Abstract: Detection units and methods for detecting one or more target analytes in a sample are disclosed. The detection unit provides a first and second surface connected by a filament which is capable of binding the target analyte in the sample. The methods provide for the detection of the target analyte through the generation of a detectable signal following the binding of the target analyte to the filament.Type: ApplicationFiled: October 10, 2012Publication date: September 18, 2014Inventor: Alfredo Andres Celedon
-
Publication number: 20140099635Abstract: The present application relates to detection units and methods for detecting one or more target analytes in a sample. In certain embodiments, the detection unit provides a first and second surface connected by a filament which is capable of binding the target analyte in the sample. In other embodiments, the detection unit provides a circular molecule capable of binding the target analyte and accumulating torsional stress in the presence of a twisting agent. The methods provide for the detection of the target analyte through the generation of a detectable signal following the binding of the target analyte to the filament.Type: ApplicationFiled: September 24, 2013Publication date: April 10, 2014Inventor: Alfredo Andres Celedon