Patents by Inventor Alfredo Garzino-Demo

Alfredo Garzino-Demo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Directional induction of immune response by co-administration of antigens with chemokines
    Patent number: 7708983
    Abstract: The present invention relates to compositions and methods of using same to direct an immune response thereby enhancing the efficacy of an antigen containing vaccine by combining a chemokine in conjunction with the vaccine, wherein the choice of the chemokine directs the immune response in either the Th1 or Th2 direction.
    Type: Grant
    Filed: July 19, 2006
    Date of Patent: May 4, 2010
    Inventors: Alfredo Garzino-Demo, Robert C. Gallo, Anthony L. Devico
  • Immuno-modulating effects of chemokines in DNA vaccination
    Patent number: 7384641
    Abstract: The present invention relates to a composition and method for enhancing the efficacy of a vaccine in a subject treated with the vaccine by administering to the subject an antigen in conjunction with a chemokine.
    Type: Grant
    Filed: March 4, 2005
    Date of Patent: June 10, 2008
    Assignee: University of Maryland Biotechnology Institute
    Inventors: Alfredo Garzino-Demo, Anthony L. DeVico
  • Directional induction of immune response by co-administration of antigens with chemokines
    Publication number: 20080112976
    Abstract: The present invention relates to compositions and methods of using same to direct an immune response thereby enhancing the efficacy of an antigen containing vaccine by combining a chemokine in conjunction with the vaccine, wherein the choice of the chemokine directs the immune response in either the Th1 or Th2 direction.
    Type: Application
    Filed: July 19, 2006
    Publication date: May 15, 2008
    Inventors: Alfredo Garzino-Demo, Robert C. Gallo, Anthony L. Devico
  • Immuno-modulating effects of chemokines in DNA vaccination
    Publication number: 20050208017
    Abstract: The present invention relates to a composition and method for enhancing the efficacy of a vaccine in a subject treated with the vaccine by administering to the subject an antigen in conjunction with a chemokine.
    Type: Application
    Filed: March 4, 2005
    Publication date: September 22, 2005
    Inventors: Alfredo Garzino-Demo, Anthony DeVico
  • Immuno-modulating effects of chemokines in DNA vaccination
    Patent number: 6919319
    Abstract: The present invention relates to a composition and method for enhancing the efficacy of a vaccine in a subject treated with the vaccine by administering to the subject an antigen in conjunction with a chemokine.
    Type: Grant
    Filed: May 27, 2003
    Date of Patent: July 19, 2005
    Assignee: University of Maryland Biotechnology Institute
    Inventors: Alfredo Garzino-Demo, Anthony L. DeVico
  • IMMUNO-MODULATING EFFECTS OF CHEMOKINES IN DNA VACCINATION
    Publication number: 20040197305
    Abstract: The present invention relates to a composition and method for enhancing the efficacy of a vaccine in a subject treated with the vaccine by administering to the subject an antigen in conjunction with a chemokine.
    Type: Application
    Filed: May 27, 2003
    Publication date: October 7, 2004
    Inventors: Alfredo Garzino-Demo, Anthony L. DeVico
  • Immuno-modulating effects of chemokines in DNA vaccination
    Patent number: 6569418
    Abstract: The present invention relates to a composition and method for enhancing the efficacy of a vaccine in a subject treated with the vaccine by administering to the subject an antigen in conjunction with a chemokine.
    Type: Grant
    Filed: June 12, 2000
    Date of Patent: May 27, 2003
    Assignee: University of Maryland Biotechnology Institute
    Inventors: Alfredo Garzino-Demo, Anthony L. DeVico
  • Macrophage derived chemokine (MDC) as an anti-viral agent for the treatment and prevention of lentivirus infection
    Patent number: 6548631
    Abstract: The present invention relates to therapeutic compositions of macrophage derived chemokine (MDC) and methods for treating and preventing infection by a lentivirus, particularly an immunodeficiency virus, particularly HIV, using MDC proteins, nucleic acids and/or derivatives or analogues thereof. The present invention further relates to methods for detection and prognosis of lenivirus infection, particularly HIV infection using MDC as a prognostic indicator. The present invention further provides MDC proteins, nucleic acids encoding such proteins, that have amino-terminal sequences that differ from other MDC isolates. Recombinant host cells and methods of production are also provided.
    Type: Grant
    Filed: September 16, 1997
    Date of Patent: April 15, 2003
    Assignee: bioMérieux, Inc.
    Inventors: Anthony L. DeVico, Ranajit Pal, Robert C. Gallo, Phillip D. Markham, Alfredo Garzino-Demo
  • Diagnostic method for distinguishing HIV-associated dementia from other forms of dementia
    Patent number: 6541208
    Abstract: The HIV-1 transactivator protein Tat significantly increases astrocytic expression and release of monocyte chemoattractant protein-1. Monocyte chemoattractant protein-1 (MCP-1) is expressed in the brains of patients with HIV-1-associated dementia, and is present in the cerebrospinal fluid of patients with this condition. This present invention employs compounds, such as MCP-1 antagonists and partial agonists, as well as HIV-1 Tat-inhibitors in methods for treating and/or preventing HIV-1 associated dementia.
    Type: Grant
    Filed: March 17, 1998
    Date of Patent: April 1, 2003
    Assignee: University of Maryland Biotechnology Institute
    Inventor: Alfredo Garzino-Demo
  • Chemokine inhibition of immunodeficiency virus
    Patent number: 6428970
    Abstract: The invention relates to therapeutic compositions and methods for treating and preventing infection by an immunodeficiency virus, particularly HIV infection, using chemokine proteins, nucleic acids and/or derivatives or analogs thereof.
    Type: Grant
    Filed: December 22, 2000
    Date of Patent: August 6, 2002
    Assignee: University of Maryland Biotechnology Institute
    Inventors: Anthony De Vico, Alfredo Garzino-Demo, Robert C. Gallo
  • Chemokine inhibition of immunodeficiency virus
    Publication number: 20010006681
    Abstract: The invention relates to therapeutic compositions and methods for treating and preventing infection by an immunodeficiency virus, particularly HIV infection, using chemokine proteins, nucleic acids and/or derivatives or analogs thereof.
    Type: Application
    Filed: December 22, 2000
    Publication date: July 5, 2001
    Inventors: Anthony De Vico, Alfredo Garzino-Demo, Robert C. Gallo
  • Chemokines that inhibit immunodeficiency virus infection and methods based thereon
    Patent number: 6214540
    Abstract: The present invention relates to therapeutic compositions and methods for treating and preventing infection by an immunodeficiency virus, particularly HIV infection, using chemokine proteins, nucleic acids and/or derivatives or analogues thereof.
    Type: Grant
    Filed: March 26, 1997
    Date of Patent: April 10, 2001
    Assignee: University of Maryland Biotechnology Institute
    Inventors: Anthony L. DeVico, Robert C. Gallo, Alfredo Garzino-Demo