Patents by Inventor Alfredo Grossi

Alfredo Grossi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • CONCENTRATED LIQUID PHARMACEUTICAL FORMULATIONS OF FUROSEMIDE AND METHODS OF ADMINISTERING THE SAME
    Publication number: 20240325411
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Application
    Filed: April 26, 2024
    Publication date: October 3, 2024
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo Olajimi Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • CONCENTRATED LIQUID PHARMACEUTICAL FORMULATIONS OF FUROSEMIDE AND METHODS OF ADMINISTERING THE SAME
    Publication number: 20240316070
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Application
    Filed: June 6, 2024
    Publication date: September 26, 2024
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo Olajimi Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • CONCENTRATED LIQUID PHARMACEUTICAL FORMULATIONS OF FUROSEMIDE AND METHODS OF ADMINISTERING THE SAME
    Publication number: 20240316071
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Application
    Filed: June 6, 2024
    Publication date: September 26, 2024
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo Olajimi Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • CONCENTRATED LIQUID PHARMACEUTICAL FORMULATIONS OF FUROSEMIDE AND METHODS OF ADMINISTERING THE SAME
    Publication number: 20240307417
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Application
    Filed: May 22, 2024
    Publication date: September 19, 2024
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo Olajimi Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • CONCENTRATED LIQUID PHARMACEUTICAL FORMULATIONS OF FUROSEMIDE AND METHODS OF ADMINISTERING THE SAME
    Publication number: 20240299419
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Application
    Filed: May 17, 2024
    Publication date: September 12, 2024
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo Olajimi Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • Concentrated liquid pharmaceutical formulations of furosemide and methods of administering the same
    Patent number: 12048709
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Grant
    Filed: January 5, 2023
    Date of Patent: July 30, 2024
    Assignee: scPharmaceuticals Inc.
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo Olajimi Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • Concentrated liquid pharmaceutical formulations of furosemide and methods of administering the same
    Patent number: 11998555
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Grant
    Filed: January 30, 2020
    Date of Patent: June 4, 2024
    Assignee: scPharmaceuticals Inc.
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo O. Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • Stable Solid Formulation of GC-C Receptor Agonist Polypeptide Suitable for Oral Administration
    Publication number: 20230310329
    Abstract: Solid, stable formulations of linaclotide suitable for oral administration are described herein as are methods for preparing such formulations. The formulations described herein contain a polypeptide consisting of the amino acid sequence Cys Cys Glu Tyr Cys Cys Asn Pro Ala Cys Thr Gly Cys Tyr (“linaclotide”; SEQ ID NO:1) or a pharmaceutically acceptable salt thereof. The linaclotide formulations described herein are stable and have a sufficient shelf life for manufacturing, storing and distributing the drug.
    Type: Application
    Filed: April 14, 2023
    Publication date: October 5, 2023
    Inventors: Angelika Fretzen, Steven Witowski, Alfredo Grossi, Hong Zhao, Mahendra Dedhiya, Yun Mo
  • CONCENTRATED LIQUID PHARMACEUTICAL FORMULATIONS OF FUROSEMIDE AND METHODS OF ADMINISTERING THE SAME
    Publication number: 20230277558
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Application
    Filed: January 5, 2023
    Publication date: September 7, 2023
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo Olajimi Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • PHARMACEUTICAL COMPOSITION AND ADMINISTRATIONS THEREOF
    Publication number: 20230210839
    Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
    Type: Application
    Filed: December 30, 2022
    Publication date: July 6, 2023
    Applicant: Vertex Pharmaceuticals Incorporated
    Inventors: William Rowe, Patricia Hurter, Christopher Young, Kirk Dinehart, Marinus Jacobus Verwijs, Kirk Overhoff, Peter D.J. Grootenhuis, Martyn Botfield, Alfredo Grossi
  • Concentrated liquid pharmaceutical formulations of furosemide
    Patent number: 11571434
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Grant
    Filed: August 2, 2022
    Date of Patent: February 7, 2023
    Assignee: scPharmaceuticals Inc.
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo O. Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • Pharmaceutical composition and administrations thereof
    Patent number: 11564916
    Abstract: The present invention relates to pharmaceutical compositions comprising a solid dispersion of N-[2,4-Bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide, methods of manufacturing pharmaceutical compositions of the present invention, and methods of administering pharmaceutical compositions of the present invention.
    Type: Grant
    Filed: April 7, 2020
    Date of Patent: January 31, 2023
    Assignee: Vertex Pharmaceuticals Incorporated
    Inventors: William Rowe, Patricia Hurter, Christopher Young, Kirk Dinehart, Marinus Jacobus Verwijs, Kirk Overhoff, Peter D. J. Grootenhuis, Martyn Botfield, Alfredo Grossi
  • Concentrated liquid pharmaceutical formulations of furosemide
    Patent number: 11559535
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Grant
    Filed: August 5, 2022
    Date of Patent: January 24, 2023
    Assignee: scPharmaceuticals Inc.
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo O. Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • CONCENTRATED LIQUID PHARMACEUTICAL FORMULATIONS OF FUROSEMIDE
    Publication number: 20220378806
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Application
    Filed: August 2, 2022
    Publication date: December 1, 2022
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo O. Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • CONCENTRATED LIQUID PHARMACEUTICAL FORMULATIONS OF FUROSEMIDE
    Publication number: 20220378805
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Application
    Filed: August 5, 2022
    Publication date: December 1, 2022
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo O. Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • Concentrated liquid pharmaceutical formulations of furosemide
    Patent number: 11497755
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Grant
    Filed: February 18, 2022
    Date of Patent: November 15, 2022
    Assignee: scPharmaceuticals Inc.
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo O. Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • CONCENTRATED LIQUID PHARMACEUTICAL FORMULATIONS OF FUROSEMIDE
    Publication number: 20220168323
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Application
    Filed: February 18, 2022
    Publication date: June 2, 2022
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo O. Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • Stable Solid Formulation of GC-C Receptor Agonist Polypeptide Suitable for Oral Administration
    Publication number: 20220125734
    Abstract: Solid, stable formulations of linaclotide suitable for oral administration are described herein as are methods for preparing such formulations. The formulations described herein contain a polypeptide consisting of the amino acid sequence Cys Cys Glu Tyr Cys Cys Asn Pro Ala Cys Thr Gly Cys Tyr (“linaclotide”; SEQ ID NO:1) or a pharmaceutically acceptable salt thereof. The linaclotide formulations described herein are stable and have a sufficient shelf life for manufacturing, storing and distributing the drug.
    Type: Application
    Filed: January 7, 2022
    Publication date: April 28, 2022
    Inventors: Angelika Fretzen, Steven Witowski, Alfredo Grossi, Hong Zhao, Mahendra Dedhiya, Yun Mo
  • CONCENTRATED LIQUID PHARMACEUTICAL FORMULATIONS OF FUROSEMIDE AND METHODS OF ADMINISTERING THE SAME
    Publication number: 20220096500
    Abstract: Disclosed herein, in part, are liquid pharmaceutical formulations comprising furosemide or a pharmaceutically acceptable salt thereof, one or more pharmaceutically acceptable excipients, and a pharmaceutically acceptable buffer. Methods of treating congestion, edema, fluid overload, or hypertension in a patient in need thereof are also provided.
    Type: Application
    Filed: January 30, 2020
    Publication date: March 31, 2022
    Inventors: Alfredo Grossi, Britt Kostraba, Olatokumbo O. Luca Ogunleye, Shannon Terry, Franciscus Koppenhagen
  • STORAGE STABLE SOMATOSTATIN-DOPAMINE CHIMERIC COMPOUNDS AND SALT FORMS THEREOF
    Publication number: 20210338782
    Abstract: The disclosure provides storage-stable somatostatin-dopamine chimeric analog compounds and storage-stable pharmaceutical compositions thereof for use in treating endocrine diseases and endocrine tumors.
    Type: Application
    Filed: May 14, 2021
    Publication date: November 4, 2021
    Inventors: Alfredo GROSSI, Heather HALEM, Niels SVENSTRUP, Valerie CWYNAR