Abstract: A cap for a syringe with Luer-lock connector comprising: a main body provided with a first handle portion and a second portion having an external threading for coupling with a corresponding internal threading of the Luer-lock connector of the syringe, an axial cavity having an aperture at the second coupling portion being formed in the main body; and a rubber housed in the axial cavity of the main body. The rubber has a surface facing the aperture of the axial cavity and designed to abut against an open free end of a tip of the syringe for air-tightly closing the open free end and raised elements are formed at the external threading of the second coupling portion.

Abstract: A dosing syringe including a hollow cylindrical body and a plunger sliding within the hollow cylindrical body. The hollow cylindrical body includes a main body and a proximal end provided with an aperture. The main body has at least one portion having a cross-section smaller than that of the proximal end, whereby a surface is delimited between the main body and the proximal end, which is configured to abut against a corresponding surface of an adapter, so that the proximal end is removable and liquid-tight blocked between said surface of the adapter and a bottom wall provided with an aperture of the adapter, the aperture of the proximal end and the aperture of the bottom wall being in direct fluid communication therebetween. An adapter for use with a dosing syringe as defined above and an administration kit including the dosing syringe and the relative adapter are also provided.

Abstract: A method for validating a homogenizing valve (1), comprising the steps of: —preparing an emulsion having a hydrophilic phase comprising, in weight percentage on the total weight: from 55% to 74% demineralized water, from 10% to 20% glycerin and from 3% to 4,2% butylene glycol, and a lipophilic phase comprising, in weight percentage on the total weight: from 5.1% to 5.9% squalane, from 7.2% to 8.8% caprylic acid alkyl ester and from 0.665% to 0.735% cetyl alcohol; —subjecting the emulsion to forced passage within the homogenizing valve (1) from a high pressure zone (HP) to a low pressure zone (LP) a plurality of times.

Abstract: A cap for a pre-filled syringe with a Luer-lock connector including a main body provided with a first handle portion and a second portion designed to be coupled to the Luer-lock connector, an axial cavity having an aperture at the second coupling portion formed in the main body; and a rubber housed within the axial cavity of said main body. The cap also includes a tapered portion, which is interposed between the first handle portion and the second coupling portion and is designed to air-tightly engage the Luer-lock connector, and the rubber has a surface facing the aperture of the axial cavity, the surface being designed to abut against an open free end of a tip of the pre-filled syringe for air-tightly closing the open free end.

Abstract: A dosing syringe including a hollow cylindrical body and a plunger slidable within the hollow cylindrical body. The dosing syringe includes at least one slider slidable within a distal flange of the hollow cylindrical body transversely to the hollow cylindrical body and at least one wall is formed in the plunger for abutting and blocking the slider during its sliding within the flange, wherein the at least one wall provides a mechanical stop which stops the stroke of the plunger at a predetermined volume of product to be aspirated and/or dispensed.

Abstract: A medical device (100) for the instillation of medical products in droplet form is described, said device comprising a hollow cylindrical body (10) and a rod (20) slidably mobile inside the hollow cylindrical body (10) and provided with a head (21) on which a rubber washer (40) is fixed, which washer, during the sliding of the rod (20), is in contact with an inner surface of the hollow cylindrical body (10). The rod (20) is formed as two portions (22, 24) of different diameter and the device (100) further comprises a sealing bush (30) between the hollow cylindrical body (10) and the rod (20), wherein there is provided a stop (32) which prevents the passage of the portion (22) with a larger circular section of the rod (20).

Abstract: A medical device (100) for the instillation of medical products in droplet form is described, said device comprising a hollow cylindrical body (10) and a rod (20) slidably mobile inside the hollow cylindrical body (10) and provided with a head (21) on which a rubber washer (40) is fixed, which washer, during the sliding of the rod (20), is in contact with an inner surface of the hollow cylindrical body (10). The rod (20) is formed as two portions (22, 24) of different diameter and the device (100) further comprises a sealing bush (30) between the hollow cylindrical body (10) and the rod (20), wherein there is provided a stop (32) which prevents the passage of the portion (22) with a larger circular section of the rod (20).

Abstract: A homogenizing apparatus (1) comprising: —an inlet (2) for receiving a pressurized fluid, possibly also containing solid particles; —a zone wherein homogenization of the fluid takes place; —an outlet (10) for the fluid at a lower pressure with respect to the inlet pressure, wherein, in the homogenization zone, the fluid passes from a zone having a larger diameter (or volume) to a zone having a smaller diameter (or volume), the homogenization zone comprising an interacting element (9) shared by a first stage (equipped with a first deflector plug (6)) and a second stage suitable for creating back pressure (equipped with a second deflector plug (12)), where the deflector plugs (6 and 12) operate with the interacting element (9) they share, generating an increase in the shear rate within the first stage. The invention also concerns a homogenization process.

Abstract: A drain valve (10) implantable surgically in the eye (O) of a patient for the treatment of glaucoma, comprising a main body (11), and a drainage tube (12), connected at one end with the main body (11) and provided to be implanted in the eye (O) so as to penetrate with its distal tip inside the anterior chamber (CA) of the eye globe (GO), so as to allow the drainage outwards of the aqueous humour (UA), wherein the valve (10) is characterized by a series of significant improvements, including: 1) an extractable configuration (12a, 12b) of the drainage tube (12), to allow the adaptation (f1) of the length of the drainage tube (12) during the surgical operation to implant the valve (10); 2) a flattened or flat shape in section (12?) of the drainage tube (12, 12a, 12b) suitable for reducing the dimensions in the radial direction (IR) of the drainage tube (12) with respect to the surface of the eye globe (GO); 3) a connection free from encumbrances between the tip portion (12f) of the drainage tube (12), provide

Abstract: A drain valve (10) implantable surgically in the eye (O) of a patient for the treatment of glaucoma, comprising a main body (11), and a drainage tube (12), connected at one end with the main body (11) and provided to be implanted in the eye (O) so as to penetrate with its distal tip inside the anterior chamber (CA) of the eye globe (GO), so as to allow the drainage outwards of the aqueous humour (UA), wherein the valve (10) is characterised by a series of significant improvements, including: 1) an extractable configuration (12a, 12b) of the drainage tube (12), to allow the adaptation (f1) of the length of the drainage tube (12) during the surgical operation to implant the valve (10); 2) a flattened or flat shape in section (12?) of the drainage tube (12, 12a, 12b) suitable for reducing the dimensions in the radial direction (IR) of the drainage tube (12) with respect to the surface of the eye globe (GO); 3) a connection free from encumbrances between the tip portion (12f) of the drainage tube (12), provided t

Abstract: A homogenizing apparatus (1) comprising: —an inlet (2) for receiving a pressurized fluid, possibly also containing solid particles; —a zone wherein homogenization of the fluid takes place; —an outlet (10) for the fluid at a lower pressure with respect to the inlet pressure, wherein, in the homogenization zone, the fluid passes from a zone having a larger diameter (or volume) to a zone having a smaller diameter (or volume), the homogenization zone comprising an interacting element (9) shared by a first stage (equipped with a first deflector plug (6)) and a second stage suitable for creating back pressure (equipped with a second deflector plug (12)), where the deflector plugs (6 and 12) operate with the interacting element (9) they share, generating an increase in the shear rate within the first stage. The invention also concerns a homogenization process.

Abstract: Stable complexes are described, formed by mono- and di-functional compounds bound to nanoparticles composed of various types of transition metal oxides and of metals useful in the production processes of different types of new materials (such as for example some types of hydrophile plastics, fibers); processes for the production of the complexes are also described.

Abstract: There are described nanoparticles of magnetic metal oxides employable in constructs consisting in polymer particles possibly also incorporating pharmacologically active substances.

Abstract: There are described nanoparticles of magnetic metal oxides employable in constructs consisting in polymer particles possibly also incorporating pharmacologically active substances.

Abstract: Stable complexes are described, formed by mono- and di-functional compounds bound to nanoparticles composed of various types of transition metal oxides and of metals useful in the production processes of different types of new materials (such as for example some types of hydrophile plastics, fibres); processes for the production of the complexes are also described.