Abstract: A computer-implemented method includes receiving from a user over a network a media file including a recorded patient screening interview, receiving from the user over the network data comprising one or more responses provided by the patient to a mental health questionnaire, generating a transcription of audio associated with the media file, presenting to the patient via a graphical user interface (GUI) a first question of the set of questions, performing video sentiment analysis to generate a second data set, presenting to the patient via a graphical user interface (GUI) the second set of questions based on at least one of the transcription, first and/or second data, generating an artificial intelligence model configured to determine a score characterizing a relevance of a mental health topic to the patient and provide predicted risk levels for one or more mental health conditions based on the patient's first and second set of answers.

Abstract: A method implements an artificial intelligence powered chief of staff bot. The method involves receiving natural language input. The method further involves processing the natural language input using a language model to generate strategy map nodes. The method further involves processing the strategy map nodes and a strategy map to determine a mapping of the strategy map nodes to the strategy map. The method further involves processing user input to generate an updated mapping of the strategy map nodes. The method further involves applying the updated mapping to the strategy map to generate an updated strategy map.

Abstract: Provided are methods for delivering lipid nanoparticles (LNPs) to a lung cell of a subject suffering from or at risk for primary ciliary dyskinesia (PCD), wherein the method comprises nebulizing a liquid pharmaceutical composition to generate an aerosolized pharmaceutical composition, and administering the aerosolized pharmaceutical composition to the subject.

Abstract: A computer-implemented method includes receiving patient responses over a network from a recorded screening interview, utilizing a custom Large Language Model (LLM) to generate transcriptions and insights from the audio, performing video sentiment analysis to assess emotional states, and based on these data, generating an AI model to predict risk levels for various mental health conditions. The method further comprises presenting personalized questions based on previous screening insights, creating longitudinal summaries of patient histories, continuously improving the AI models through reinforcement learning, and integrating a recommendation engine to suggest targeted interventions. Additionally, the method includes tracking outcomes over time and enabling causal inference across multiple screenings, thereby providing a comprehensive platform for mental health assessment, intervention, and outcomes tracking.

Abstract: Provided are a method for quantifying an amount of capped messenger RNA (mRNA) in an mRNA sample comprising contacting the mRNA with two or more of a nuclease, an alkaline phosphatase, and a polynucleotide kinase and separating the capped mRNA and the uncapped mRNA occurs using chromatography.

Abstract: A controller for controlling an autonomous vehicle. The controller comprises a reconfigurable intelligent surface (RIS) transceiver configured to receive RIS signals from a RIS device, a positioning signal receiver configured to receive positioning signals from a positioning signal transmitter, and a processor. The processor is configured to process the RIS signals to produce RIS data, process the positioning signals to produce positioning data, fuse the RIS data and the positioning data using a data fusion algorithm to compute a location of the autonomous vehicle, and control operation of the autonomous vehicle based on the computed location.

Abstract: The disclosed LiDAR systems and methods are for object detection. The LiDAR method comprising: i) transmitting a light signal x(t) towards a region of interest (ROI); ii) receiving a reflected light signal and ambient noise signal, the reflected light signal including reflected light pulses reflected from at least one object in the ROI and the ambient noise signal including light signals that are not generated by the light source; iii) detecting one or more photons in the reflected light signal and/or the ambient noise signal and generating a SPAD output signal; iv) converting the SPAD output signal to a digital signal; v) determining a location of the at least one object based on the digital signal; and vi) varying a diameter of an opening defined by the tunable aperture in accordance with the ambient noise signal and operational parameters associated with the LIDAR system.

Abstract: A multiphase wireless power transfer pad has at least a first coil and a second coil and permeable material which includes a region of reduced magnetic permeability configured to minimise coupling between the first and second coils.

Abstract: Aspects of the disclosure provide a method of a LiDAR system to determine the distance of an object from the LiDAR system. Embodiments of the LiDAR system can use a coarse estimate of the distance of an object from the LiDAR system which is then used by a fast search to determine an estimate of the distance of an object from the LiDAR system within a precision threshold. In some embodiments the LiDAR system can use adaptive precision when determining the distance of an object from the LiDAR system.

Abstract: Disclosed is a zero-knowledge distributed application configured to securely share information among groups of users having various roles, such as doctors and patients. Confidential information may be encrypted client-side, with private keys that reside solely client side. Encrypted collections of data may be uploaded to, and hosted by, a server that does not have access to keys suitable to decrypt the data. Other users may retrieve encrypted data from the server and decrypt some or all of the data with keys suitable to gain access to at least part of the encrypted data. The system includes a key hierarchy with multiple entry points to a top layer by which access is selectively granted to various users and keys may be recovered.

Abstract: Provided are methods for delivering lipid nanoparticles (LNPs) to a lung cell of a subject suffering from or at risk for primary ciliary dyskinesia (PCD), wherein the method comprises nebulizing a liquid pharmaceutical composition to generate an aerosolized pharmaceutical composition, and administering the aerosolized pharmaceutical composition to the subject.

Abstract: A method and system of generating a virtual model of a subterranean region is disclosed. The method may include obtaining characteristics of a plurality of sample points within a first wellbore traversing a subterranean region and for each sample point within the plurality of sample points, assigning a geological category based, at least in part, on the characteristics of the sample point, and assigning a petrophysical category based, at least in part, on the characteristics of the sample point. The method may further include assigning a hybrid category based, at least in part, on the geological category and the petrophysical category and generating the virtual model of a subterranean region of interest based, at least in part, on the hybrid category assigned to each sample point in the plurality of sample points.

Abstract: The disclosed LiDAR systems and methods are for object detection. The LiDAR system for object detection comprising: i) a receiver configured to receive a light signal reflected from an object; ii) a digital converter configured to convert the received light signal into a digital signal; iii) a pre-processor configured to pre-process the digital signal based on median filtering and to generate a pre-processed signal corresponding to the digital signal; and iv) a processor configured to analyze the pre-processed signal based on a threshold technique to detect a presence of the object.

Abstract: A method for estimating relative humidity inside an electrical machine includes determining a measured rate of change (ROC) of temperature inside an electrical machine. A ratio of the measured ROC to a reference ROC is calculated, where the ratio is equal to an average specific heat of the electrical machine. The average specific heat of the electrical machine and an air temperature value are then compared to known specific heat values of dry air and water corresponding to a known relative humidity values for a range of air temperatures. A relative humidity value inside the electrical machine is estimated based on the comparison.

Abstract: Provided are methods for delivering lipid nanoparticles (LNPs) to a lung cell of a subject suffering from or at risk for primary ciliary dyskinesia (PCD), wherein the method comprises nebulizing a liquid pharmaceutical composition to generate an aerosolized pharmaceutical composition, and administering the aerosolized pharmaceutical composition to the subject.

Abstract: There is provided a method and device for time-of-flight (TOF) ranging. The method includes generating, by each photon detector in a photon detector array, a quantized current pulse each time a predefined number of photons is detected. The method further includes summing, by a current adder, the quantized current pulses from all photon detectors to create an analog signal pulse. The method further includes providing, by a peak detector, a digital pulse for each instance where an intensity of the analog signal pulse is greater than signal peaks already measured after the last emitted pulsed laser shot. The method further includes measuring and recording, by a time-to-digital converter (TDC), a TOF each time the digital pulse is provided. The method further includes providing, by a TOF output, a single TDC result indicative of a TOF associated with the analog signal pulse having a highest intensity.

Abstract: A method collects and presents hierarchical data. The method includes receiving objective user inputs applied to a set of objective objects of a set of objects, receiving topic user inputs applied to a set of topic objects of the set of objects, and receiving settlement user inputs applied to a set of settlement objects of the set of objects. The method further includes applying a guidance categorization model to a guidance object of the set of topic objects to a generate a guidance label for the guidance object, applying a blocker categorization model to a blocker object of the set of topic objects to generate a blocker label for the blocker object, and applying a diagram metrics model to the set of objects to generate diagram metrics data. The method further includes presenting a topic diagram using the guidance label, the blocker label, and the diagram metrics data.

Abstract: Disclosed is a zero-knowledge distributed application configured to securely share information among groups of users having various roles, such as doctors and patients. Confidential information may be encrypted client-side, with private keys that reside solely client side. Encrypted collections of data may be uploaded to, and hosted by, a server that does not have access to keys suitable to decrypt the data. Other users may retrieve encrypted data from the server and decrypt some or all of the data with keys suitable to gain access to at least part of the encrypted data. The system includes a key hierarchy with multiple entry points to a top layer by which access is selectively granted to various users and keys may be recovered.

Abstract: A method of controlling a polyphase wireless power transfer coupler includes using duty cycle control to switch a polyphase converter to produce a periodic asymmetric voltage waveform across the phase windings.

Abstract: Provided are methods for delivering lipid nanoparticles (LNPs) to a lung cell of a subject suffering from or at risk for cystic fibrosis (CF), wherein the method comprises nebulizing a liquid pharmaceutical composition to generate an aerosolized pharmaceutical composition, and administering the aerosolized pharmaceutical composition to the subject, wherein the LNPs comprise mRNA encoding a Cystic Fibrosis Transmembrane conductance Regulator (CFTR) protein.