Patents by Inventor Ali ALHOSHANI
Ali ALHOSHANI has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11571430Abstract: A platinum(II) complex of formula (I), or a pharmaceutically acceptable solvate or tautomer thereof, wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; or wherein R1 and R2 together form a five-, six-, or seven-membered ring with the nitrogen atoms to which they are attached; and X is a nitrate anion, a hexafluorophosphate anion, a hexafluoroantimonate anion, a trifluoromethanesulfonate anion, a tetrafluoroborate anion, a perchlorate anion, or a halide anion. A pharmaceutical composition containing the platinum(II) complex of formula (I), and a method of treating cancer are also disclosed.Type: GrantFiled: February 1, 2021Date of Patent: February 7, 2023Assignees: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITYInventors: Adam Ahmed Abdullah Sulaiman, Abdul Rajjak Shaikh, Ali Alhoshani, Anvarhusein A. Isab
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Patent number: 11142539Abstract: Mixed ligand phosphinogold(I) complexes as anticancer agents. The gold(I) ion of the complexes is coordinated to a phosphine and a dithiocarbamate or halogen ligand. Also described are a pharmaceutical composition incorporating the phosphinogold(I) complex, a method of synthesizing the phosphinogold(I) complex, and a method of treating cancer. The phosphinogold(I) complexes exhibit potent cytotoxicity against lung, cervical, and liver cancer cells.Type: GrantFiled: March 10, 2020Date of Patent: October 12, 2021Assignees: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Anvarhusein A. Isab, Adam Ahmed Abdullah Sulaiman, Ali Alhoshani
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Publication number: 20210284674Abstract: Mixed ligand phosphinogold(I) complexes as anticancer agents. The gold(I) ion of the complexes is coordinated to a phosphine and a dithiocarbamate or halogen ligand. Also described are a pharmaceutical composition incorporating the phosphinogold(I) complex, a method of synthesizing the phosphinogold(I) complex, and a method of treating cancer. The phosphinogold(I) complexes exhibit potent cytotoxicity against lung, cervical, and liver cancer cells.Type: ApplicationFiled: March 10, 2020Publication date: September 16, 2021Applicants: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Anvarhusein A. ISAB, Adam Ahmed Abdullah SULAIMAN, Ali ALHOSHANI
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Publication number: 20210283140Abstract: A platinum(II) complex of formula (I), or a pharmaceutically acceptable solvate or tautomer thereof, wherein R1 and R2 are each independently a hydrogen, an optionally substituted alkyl, an optionally substituted cycloalkyl, an optionally substituted arylalkyl, or an optionally substituted aryl; or wherein R1 and R2 together form a five-, six-, or seven-membered ring with the nitrogen atoms to which they are attached; and X is a nitrate anion, a hexafluorophosphate anion, a hexafluoroantimonate anion, a trifluoromethanesulfonate anion, a tetrafluoroborate anion, a perchlorate anion, or a halide anion. A pharmaceutical composition containing the platinum(II) complex of formula (I), and a method of treating cancer are also disclosed.Type: ApplicationFiled: February 1, 2021Publication date: September 16, 2021Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITYInventors: Adam Ahmed Abdullah SULAIMAN, Abdul Rajjak SHAIKH, Ali ALHOSHANI, Anvarhusein A. ISAB
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Publication number: 20210284671Abstract: A family of platinum(II) complex with mixed ligands as anticancer agents. The platinum(II) ion is coordinated to dicyclopentadiene and dithiocarbamate ligands. Also described are a pharmaceutical composition incorporating the platinum(II) complex, a methods of synthesizing the platinum(II) complex, and a method of treating cancer. The platinum(II) complexes exhibit potent cytotoxicity against lung and cervical cancer cell lines as well as low nephrotoxicity.Type: ApplicationFiled: March 10, 2020Publication date: September 16, 2021Applicants: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Adam Ahmed Abdullah Sulaiman, Ali Alhoshani, Anvarthusein A. Isab
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Patent number: 11117912Abstract: A family of platinum(II) complex with mixed ligands as anticancer agents. The platinum(II) ion is coordinated to dicyclopentadiene and dithiocarbamate ligands. Also described are a pharmaceutical composition incorporating the platinum(II) complex, a methods of synthesizing the platinum(II) complex, and a method of treating cancer. The platinum(II) complexes exhibit potent cytotoxicity against lung and cervical cancer cell lines as well as low nephrotoxicity.Type: GrantFiled: March 10, 2020Date of Patent: September 14, 2021Assignees: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Adam Ahmed Abdullah Sulaiman, Ali Alhoshani, Anvarhusein A. Isab
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Patent number: 10533029Abstract: Platinum(II) complexes with various selenones (L) having the general formula PtL2(NH3)2+2 X?2 are disclosed. The platinum(II) complexes inhibit growth of cancer cells in vitro and are useful for treatment of proliferative disorders such as cancers and/or tumors.Type: GrantFiled: September 18, 2018Date of Patent: January 14, 2020Assignee: King Fahd University of Petroleum and MineralsInventors: Anvarhusein A. Isab, Adam A. A. Sulaiman, Ali Alhoshani, Muhammad Altaf
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Patent number: 10358456Abstract: Platinum(II) complexes with various selones (L) having the general formula PtL2Cl2 are disclosed. The platinum(II) complexes of the invention inhibit growth of cancer cells in vitro and are useful for treatment of proliferative disorders such as cancers and/or tumors.Type: GrantFiled: March 22, 2018Date of Patent: July 23, 2019Assignees: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Anvarhusein A. Isab, Muhammad Altaf, Ali Alhoshani, Ali Osman Altoum, Mohammed Yagoub Jomaa
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Patent number: 10301335Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.Type: GrantFiled: August 24, 2018Date of Patent: May 28, 2019Assignees: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Said S. Al-Jaroudi, Ali Alhoshani, Muhammad Altaf, Anvarhusein Abdulkadir Isab
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Patent number: 10294254Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.Type: GrantFiled: August 24, 2018Date of Patent: May 21, 2019Assignees: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Said S. Al-Jaroudi, Ali Alhoshani, Muhammad Altaf, Anvarhusein Abdulkadir Isab
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Patent number: 10280187Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.Type: GrantFiled: August 24, 2018Date of Patent: May 7, 2019Assignees: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Said S. Al-Jaroudi, Ali Alhoshani, Muhammad Altaf, Anvarhusein Abdulkadir Isab
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Patent number: 10273257Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.Type: GrantFiled: August 24, 2018Date of Patent: April 30, 2019Assignees: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Said S. Al-Jaroudi, Ali Alhoshani, Muhammad Altaf, Anvarhusein Abdulkadir Isab
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Publication number: 20190040089Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.Type: ApplicationFiled: August 24, 2018Publication date: February 7, 2019Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITYInventors: Said S. AL-JAROUDI, Ali ALHOSHANI, Muhammad ALTAF, Anvarhusein Abdulkadir ISAB
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Publication number: 20180362555Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.Type: ApplicationFiled: August 24, 2018Publication date: December 20, 2018Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITYInventors: Said S. AL-JAROUDI, Ali ALHOSHANI, Muhammad ALTAF, Anvarhusein Abdulkadir ISAB
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Publication number: 20180362556Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.Type: ApplicationFiled: August 24, 2018Publication date: December 20, 2018Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITYInventors: Said S. AL-JAROUDI, Ali ALHOSHANI, Muhammad ALTAF, Anvarhusein Abdulkadir ISAB
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Publication number: 20180362557Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.Type: ApplicationFiled: August 24, 2018Publication date: December 20, 2018Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITYInventors: Said S. Al-Jaroudi, Ali Alhoshani, Muhammad Altaf, Anvarhusein Abdulkadir Isab
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Patent number: 10144749Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.Type: GrantFiled: May 30, 2018Date of Patent: December 4, 2018Assignees: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Said S. Al-Jaroudi, Ali Alhoshani, Muhammad Altaf, Anvarhusein Abdulkadir Isab
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Patent number: 10093689Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.Type: GrantFiled: May 25, 2018Date of Patent: October 9, 2018Assignees: King Fahd University of Petroleum and Minerals, King Saud UniversityInventors: Said S. Al-Jaroudi, Ali Alhoshani, Muhammad Altaf, Anvarhusein Abdulkadir Isab
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Publication number: 20180273559Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.Type: ApplicationFiled: May 30, 2018Publication date: September 27, 2018Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITYInventors: Said S. Al-Jaroudi, Ali Alhoshani, Muhammad Altaf, Anvarhusein Abdulkadir Isab
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Publication number: 20180273558Abstract: Gold(I) complex with mixed ligands as an anticancer agent. The gold(I) ion is coordinated to a dithiocarbamate ligand and a phosphorus-containing ligand (e.g. phosphines). Also described are a pharmaceutical composition incorporating the gold(I) complex, a methods of synthesizing the gold(I) complex, and a method for treating cancer.Type: ApplicationFiled: May 25, 2018Publication date: September 27, 2018Applicants: KING FAHD UNIVERSITY OF PETROLEUM AND MINERALS, KING SAUD UNIVERSITYInventors: Said S. AL-JAROUDI, Ali ALHOSHANI, Muhammad ALTAF, Anvarhusein Abdulkadir ISAB