Abstract: A system includes acquisition of a first three-dimensional image of a patient volume using a magnetic resonance imaging scanner, acquisition of a second three-dimensional image of the patient volume using cone beam radiation emitted by the linear accelerator, and generation of a radiation treatment plan based on the first image and the second image.

Abstract: Some aspects include acquisition of a first plurality of projection images of a volume using a megavoltage x-ray source, each of the first plurality of projection images associated with a respective one of a first plurality of locations of the megavoltage x-ray source, acquisition of a second plurality of projection images of the volume using a kilovoltage x-ray source, each of the second plurality of projection images associated with a respective one of a second plurality of locations of the kilovoltage x-ray source, and performance of digital tomosynthesis reconstruction to generate a three-dimensional image of the volume based on the first plurality of projection images and the second plurality of projection images. The first axis may be perpendicular to the second axis.

Abstract: A system includes acquisition of a three-dimensional computed tomography image of a patient volume at a computed tomography scanner, acquisition of projection images of the patient volume located at an isocenter of a linear accelerator, and determination of a transformation between a coordinate system of the linear accelerator and a coordinate system of the three-dimensional computed tomography image based on the projection images.

Abstract: A system and method for tomosynthesis, the method including emitting a respective imaging x-ray from each of a plurality of imaging x-ray sources disposed in a fixed relation with respect to one another, acquiring x-ray absorption projections of an object, each of the x-ray absorption projections associated with an imaging x-ray emitted by a respective one of the plurality of imaging x-ray sources, and performing digital tomosynthesis using the x-ray absorption projections to generate a cross-sectional image of the object.

Abstract: A system includes acquisition of a three-dimensional computed tomography image of a patient volume at a computed tomography scanner, acquisition of projection images of the patient volume located at an isocenter of a linear accelerator, and determination of a transformation between a coordinate system of the linear accelerator and a coordinate system of the three-dimensional computed tomography image based on the projection images.

Abstract: A system includes acquisition of a first three-dimensional image of a patient volume using a magnetic resonance imaging scanner, acquisition of a second three-dimensional image of the patient volume using cone beam radiation emitted by the linear accelerator, and generation of a radiation treatment plan based on the first image and the second image.

Abstract: Some aspects include acquisition of a first plurality of projection images of a volume using a megavoltage x-ray source, each of the first plurality of projection images associated with a respective one of a first plurality of locations of the megavoltage x-ray source, acquisition of a second plurality of projection images of the volume using a kilovoltage x-ray source, each of the second plurality of projection images associated with a respective one of a second plurality of locations of the kilovoltage x-ray source, and performance of digital tomosynthesis reconstruction to generate a three-dimensional image of the volume based on the first plurality of projection images and the second plurality of projection images. The first axis may be perpendicular to the second axis.

Abstract: Some aspects include acquisition of a first plurality of projection images of a volume using a megavoltage x-ray source, each of the first plurality of projection images associated with a respective one of a first plurality of locations of the megavoltage x-ray source, acquisition of a second plurality of projection images of the volume using a kilovoltage x-ray source, each of the second plurality of projection images associated with a respective one of a second plurality of locations of the kilovoltage x-ray source, and performance of digital tomosynthesis reconstruction to generate a three-dimensional image of the volume based on the first plurality of projection images and the second plurality of projection images. The first axis may be perpendicular to the second axis.

Abstract: A system and method for tomosynthesis, the method including emitting a respective imaging x-ray from each of a plurality of imaging x-ray sources disposed in a fixed relation with respect to one another, acquiring x-ray absorption projections of an object, each of the x-ray absorption projections associated with an imaging x-ray emitted by a respective one of the plurality of imaging x-ray sources, and performing digital tomosynthesis using the x-ray absorption projections to generate a cross-sectional image of the object.

Abstract: A system and method for tomosynthesis, the method including emitting a respective imaging x-ray from each of a plurality of imaging x-ray sources disposed in a fixed relation with respect to one another, acquiring x-ray absorption projections of an object, each of the x-ray absorption projections associated with an imaging x-ray emitted by a respective one of the plurality of imaging x-ray sources, and performing digital tomosynthesis using the x-ray absorption projections to generate a cross-sectional image of the object.

Abstract: Some aspects include acquisition of a first plurality of projection images of a volume using a megavoltage x-ray source, each of the first plurality of projection images associated with a respective one of a first plurality of locations of the megavoltage x-ray source, acquisition of a second plurality of projection images of the volume using a kilovoltage x-ray source, each of the second plurality of projection images associated with a respective one of a second plurality of locations of the kilovoltage x-ray source, and performance of digital tomosynthesis reconstruction to generate a three-dimensional image of the volume based on the first plurality of projection images and the second plurality of projection images. The first axis may be perpendicular to the second axis.

Abstract: A system includes emission of a first plurality of radiation beams from respective ones of a first plurality of locations along a first arc, acquisition of a first plurality of projection images of a target based on the first plurality of radiation beams, emission of a second plurality of radiation beams from respective ones of a second plurality of locations along a second arc, acquisition of a second plurality of projection images of the target based on the second plurality of radiation beams, and generation of a three-dimensional image of the target based on the first plurality of projection images and the second plurality of projection images, wherein a density of the first plurality of locations along the first arc is less than the density of the second plurality of locations along the second arc.

Abstract: A system may include a biocompatible housing and an electrical circuit disposed within the housing, the electrical circuit to emit a radiofrequency signal, and wherein the electrical circuit does not comprise a metal. Also included may be a signal generator to generate a wireless signal to trigger the electrical circuit, a receiver to receive a wireless response signal generated by the triggered electrical circuit, a processor to determine a location of the biocompatible housing based on the wireless response signal, and a ion beam source to deliver a ion beam to a patient volume including the biocompatible housing.

Abstract: Some embodiments include creation of projection images of a patient volume using one or more x-ray sources, performance of digital tomosynthesis on the projection images to generate a cross-sectional image of the patient volume, determination of a location of a target within the patient volume based on the cross-sectional image, determination of a location of a Bragg peak associated with an ion beam, and determination of a difference between the location of the target and the location of the Bragg peak. In some aspects, the patient volume is moved to move the target toward the location of the Bragg peak based on the difference. Additionally or alternatively, one or more characteristics of the ion beam may be changed to move the location of the Bragg peak toward the location of the target based on the difference. The one or more radiation sources may comprise a plurality of x-ray sources disposed in a fixed relationship to each other.

Abstract: A system includes acquisition of a three-dimensional cone beam image, and determination of a dose to be delivered based on the three-dimensional image and on parameters of a treatment beam to deliver the dose. Some systems may include modification of a three-dimensional cone beam image to correct for scatter radiation, and determination of a dose based on the modified three-dimensional cone beam image.

Abstract: Some embodiments include a support movable with at least four degrees of freedom, a therapeutic radiation source coupled to the support, a plurality of radiation sources disposed in a fixed relationship to each other, the plurality of radiation sources movable in the fixed relationship with at least four degrees of freedom, a detector to acquire a projection image based on radiation emitted from one of the plurality of radiation sources, and a processor to perform digital tomosynthesis on the projection image acquired by the detector and a plurality of other projection images to generate a cross-sectional image representing a plane viewed from a perspective of the therapeutic radiation source.

Abstract: A system includes emission of a first plurality of radiation beams from respective ones of a first plurality of locations along a first arc, acquisition of a first plurality of projection images of a target based on the first plurality of radiation beams, emission of a second plurality of radiation beams from respective ones of a second plurality of locations along a second arc, acquisition of a second plurality of projection images of the target based on the second plurality of radiation beams, and generation of a three-dimensional image of the target based on the first plurality of projection images and the second plurality of projection images, wherein a density of the first plurality of locations along the first arc is less than the density of the second plurality of locations along the second arc.

Abstract: X-ray portal imaging detectors have multiple layers, such as multiple layers of phosphor screens and/or detectors. Some x-rays that pass through one layer are detected or converted into light energies in a different layer. For example, one phosphor screen is provided in front and another behind that panel detector circuitry. Light generated in each of the phosphor screens is detected by the same detector circuitry. As another example, multiple layers of phosphor screens and associated detector circuits are provided. Some x-rays passing through one layer may be detected in a different layer. High energy x-rays associated with Megavoltage sources as well as lower or higher energy x-rays may be detected.

Abstract: Some embodiments include a support movable with at least four degrees of freedom, a therapeutic radiation source coupled to the support, a plurality of radiation sources disposed in a fixed relationship to each other, the plurality of radiation sources movable in the fixed relationship with at least four degrees of freedom, a detector to acquire a projection image based on radiation emitted from one of the plurality of radiation sources, and a processor to perform digital tomosynthesis on the projection image acquired by the detector and a plurality of other projection images to generate a cross-sectional image representing a plane viewed from a perspective of the therapeutic radiation source.

Abstract: A system may comprise a plurality of imaging x-ray sources disposed in a fixed relation with respect to one another, each of the plurality of imaging x-ray sources to emit a respective imaging x-ray, an x-ray detector to acquire x-ray absorption projections of an object, each of the x-ray absorption projections associated with an imaging x-ray emitted by a respective one of the plurality of imaging x-ray sources, and a processor to perform digital tomosynthesis using the x-ray absorption projections to generate a cross-sectional image of the object.