Abstract: Provided herein are methods and systems for determining a parameter across a surface of a tissue such as a retinal tissue of an eye of a subject. In some cases, the determined parameter is tissue oxygenation which can be used for a variety of clinical applications such as diagnosing and/or modeling a disease in the subject. In some examples, the method is performed by detecting one or more optical signals from the tissue using an optical detector, and processing the detected optical signals to characterize and map the parameter across the surface of the tissue. The methods and systems provided herein can prove accurate physics-based models of parameters such as tissue oxygenation across a heterogeneous tissue surface.

Abstract: Provided herein are methods and systems for determining a parameter across a surface of a tissue such as a retinal tissue of an eye of a subject. In some cases, the determined parameter is tissue oxygenation which can be used for a variety of clinical applications such as diagnosing and/or modeling a disease in the subject. In some examples, the method is performed by detecting one or more optical signals from the tissue using an optical detector, and processing the detected optical signals to characterize and map the parameter across the surface of the tissue. The methods and systems provided herein can prove accurate physics-based models of parameters such as tissue oxygenation across a heterogeneous tissue surface.

Abstract: A fast and dynamic waveplate is described. The present systems and methods utilize stress birefringence that generates inside a plate when force is applied on one or more sides of the plate. The force is applied using one or more actuators distributed along the side(s) of the plate. The magnitude of the force can be controlled using a control unit. A generated stress birefringence is spatially varying across the plate. By carefully adjusting the force, the plate can be converted into a waveplate with an arbitrary value of retardance that is determined by the force. Since the parameter that determines the birefringence is force, a control unit can be used to apply different combinations of force values at a sub-millisecond speed to achieve fast control of the value of the birefringence as well as an orientation in the plate.

Abstract: A method of fabricating a polarization sensor is described. It includes a quarter-wave plate to convert circularly polarized light into linearly polarized light. The quarter-wave plate is realized as a metasurface. The sensor also includes a linear polarizer to analyze the light generated by the quarter wave plate, and a photodetector to receive the analyzed light. The sensor may be combined with other linear polarization sensors to form a sensor capable of complete measurement of the polarization state of incident light.

Abstract: A method of fabricating a polarization sensor is described. It includes a quarter-wave plate to convert circularly polarized light into linearly polarized light. The quarter-wave plate is realized as a metasurface. The sensor also includes a linear polarizer to analyze the light generated by the quarter wave plate, and a photodetector to receive the analyzed light. The sensor may be combined with other linear polarization sensors to form a sensor capable of complete measurement of the polarization state of incident light.

Abstract: In an embodiment, schedule layers are generated. Each schedule layer has one or more schedule entries and a precedence value. At least one schedule layer includes schedule entries that are generated in a repetitive fashion according to an epoch. A final schedule is created based on a combination of the schedule layers according to an ordering of the precedence value of respective schedule layers. Creating the final schedule includes identifying a gap in the final schedule; and filling the gap using a schedule entry from a schedule layer of the two or more schedule layers selected according to respective precedence values. A real time interface is employed to visually present the final schedule for display. The real time interface is configured to dynamically transform and render the one or more schedule entries into one or more graphical cells visually distinguished from each other based restrictions, team members, or inputs.

Abstract: An optical device is disclosed. The optical device includes a silicon substrate, an aluminum oxide layer, an aluminum layer between the silicon substrate and the aluminum oxide layer, and a metasurface nanostructure. The metasurface nanostructure may include a graphene monolayer on the aluminum oxide layer and an electrically conductive nanoantenna array in direct contact with the graphene monolayer, where each nanoantenna in the nanoantenna array may include multiple segments, each segment having one or more parameters selected to achieve simultaneous resonance in the mid-infrared and the near infrared spectral regions when the graphene monolayer is irradiated with a near infrared pump pulse and a continuous mid-infrared probe. The optical device generates mid-infrared pulses via ultrafast modulation of hot carriers in the monolayer graphene.

Abstract: An apparatus and method of measuring oxygenation of tissue in a non-invasive manner are provided. The apparatus comprises a light source configured to emit a light pattern to be projected onto the tissue, in which the light pattern comprises superimposed patterns having different patterns. A detector captures an image of a reflected light pattern which is reflected from the tissue as a result of the projected light pattern. A processor coupled to the detector can be configured to perform a transform on the image of the reflected light pattern and determine oxygenation of each of a plurality of layers of the tissue in response to the transform of the image. Polarimetry can be used in determining a change in polarization angle of light beam. Tissue oxygenation can be determined at a plurality of layers from one snapshot, for example oxygenation of retinal layers.

Abstract: An apparatus and method of measuring oxygenation of tissue in a non-invasive manner are provided. The apparatus comprises a light source configured to emit a light pattern to be projected onto the tissue, in which the light pattern comprises superimposed patterns having different patterns. A detector captures an image of a reflected light pattern which is reflected from the tissue as a result of the projected light pattern. A processor coupled to the detector can be configured to perform a transform on the image of the reflected light pattern and determine oxygenation of each of a plurality of layers of the tissue in response to the transform of the image. Polarimetry can be used in determining a change in polarization angle of light beam. Tissue oxygenation can be determined at a plurality of layers from one snapshot, for example oxygenation of retinal layers.

Abstract: A method of fabricating a polarization sensor is described. It includes a quarter-wave plate to convert circularly polarized light into linearly polarized light. The quarter-wave plate is realized as a metasurface. The sensor also includes a linear polarizer to analyze the light generated by the quarter wave plate, and a photodetector to receive the analyzed light. The sensor may be combined with other linear polarization sensors to form a sensor capable of complete measurement of the polarization state of incident light.

Abstract: A polarization sensor is described. It includes a quarter-wave plate to convert circularly polarized light into linearly polarized light. The quarter-wave plate is realized as a metasurface. The sensor also includes a linear polarizer to analyze the light generated by the quarter-wave plate, and a photodetector to receive the analyzed light. The sensor may be combined with other linear polarization sensors to form a sensor capable of complete measurement of the polarization state of incident light. An array of these sensors can be integrated directly onto image sensors to form a polarimetric imager.

Abstract: A method of determining a parameter related to a blood oxygenation of tissue may include projecting an optical pattern onto the issue, the optical pattern comprising a spatially varying component in at least one axis. A method of determining a parameter related to a blood oxygenation of tissue may include collecting a reflected optical signal from at least a first and a second wavelength range, wherein the first and the second wavelength ranges are distinct. A method of determining a parameter related to a blood oxygenation of tissue may include normalizing the reflected optical signal. A method of determining a parameter related to a blood oxygenation of tissue may include performing a transform of the reflected optical signal. A method of determining a parameter related to a blood oxygenation of tissue may include determining the parameter related to the blood oxygenation of the tissue based on the ratio and the transform.

Abstract: An optical device is disclosed. The optical device includes a silicon substrate, an aluminum oxide layer, an aluminum layer between the silicon substrate and the aluminum oxide layer, and a metasurface nanostructure. The metasurface nanostructure may include a graphene monolayer on the aluminum oxide layer and an electrically conductive nanoantenna array in direct contact with the graphene monolayer, where each nanoantenna in the nanoantenna array may include multiple segments, each segment having one or more parameters selected to achieve simultaneous resonance in the mid-infrared and the near infrared spectral regions when the graphene monolayer is irradiated with a near infrared pump pulse and a continuous mid-infrared probe. The optical device generates mid-infrared pulses via ultrafast modulation of hot carriers in the monolayer graphene.

Abstract: A polarization sensor is described. It includes a quarter-wave plate to convert circularly polarized light into linearly polarized light. The quarter-wave plate is realized as a metasurface. The sensor also includes a linear polarizer to analyze the light generated by the quarter-wave plate, and a photodetector to receive the analyzed light. The sensor may be combined with other linear polarization sensors to form a sensor capable of complete measurement of the polarization state of incident light. An array of these sensors can be integrated directly onto image sensors to form a polarimetric imager.

Abstract: Embodiments are directed towards generating and managing schedules. In at least one of the various embodiments, these schedules may be configured to schedule team members, rotating which team member is active (“on-call”). In at least one of the various embodiments, these may be employed to determine which resource is responsible to respond and/or resolve incidents that may be reported and/or detected. In at least one of the various embodiments, if a team member is determined to be the on-call or responsible team member, the notification engine may determine the methods for notify the responsible of the incidents. Schedules previews may be updated in real-time as the schedule is edited.

Abstract: An apparatus and method of measuring oxygenation of tissue in a non-invasive manner are provided. The apparatus comprises a light source configured to emit a light pattern to be projected onto the tissue, in which the light pattern comprises superimposed patterns having different patterns. A detector captures an image of a reflected light pattern which is reflected from the tissue as a result of the projected light pattern. A processor coupled to the detector can be configured to perform a transform on the image of the reflected light pattern and determine oxygenation of each of a plurality of layers of the tissue in response to the transform of the image. Polarimetry can be used in determining a change in polarization angle of light beam. Tissue oxygenation can be determined at a plurality of layers from one snapshot, for example oxygenation of retinal layers.

Abstract: Embodiments are directed towards generating and managing schedules. In at least one of the various embodiments, these schedules may be configured to schedule team members, rotating which team member is active (“on-call”). In at least one of the various embodiments, these may be employed to determine which resource is responsible to respond and/or resolve incidents that may be reported and/or detected. In at least one of the various embodiments, if a team member is determined to be the on-call or responsible team member, the notification engine may determine the methods for notify the responsible of the incidents. Schedules previews may be updated in real-time as the schedule is edited.

Abstract: One embodiment of the present invention sets forth a technique for testing microservices in distributed computing systems. The technique includes routing a first traffic sample associated with request traffic from one or more client devices to a first instance of a first service implemented in a distributed computing system, wherein the first instance generates a first plurality of request responses in response to a first plurality of data requests included in the first traffic sample and transmits the first plurality of request responses to a second service included in the sequence of services, and routing a second traffic sample associated with the request traffic to a second instance of the first service, wherein the second instance generates a second plurality of request responses in response to a second plurality of data requests included in the second traffic sample and transmits the second plurality of request responses to the second service.

Abstract: An apparatus and method of measuring oxygenation of tissue in a non-invasive manner are provided. The apparatus comprises a light source configured to emit a light pattern to be projected onto the tissue, in which the light pattern comprises superimposed patterns having different patterns. A detector captures an image of a reflected light pattern which is reflected from the tissue as a result of the projected light pattern. A processor coupled to the detector can be configured to perform a transform on the image of the reflected light pattern and determine oxygenation of each of a plurality of layers of the tissue in response to the transform of the image. Polarimetry can be used in determining a change in polarization angle of light beam. Tissue oxygenation can be determined at a plurality of layers from one snapshot, for example oxygenation of retinal layers.

Abstract: An apparatus and method of measuring oxygenation of tissue in a non-invasive manner are provided. The apparatus comprises a light source configured to emit a light pattern to be projected onto the tissue, in which the light pattern comprises superimposed patterns having different patterns. A detector captures an image of a reflected light pattern which is reflected from the tissue as a result of the projected light pattern. A processor coupled to the detector can be configured to perform a transform on the image of the reflected light pattern and determine oxygenation of each of a plurality of layers of the tissue in response to the transform of the image. Polarimetry can be used in determining a change in polarization angle of light beam. Tissue oxygenation can be determined at a plurality of layers from one snapshot, for example oxygenation of retinal layers.