Abstract: Embodiments disclose a pore sensing fluidic device. The pore sensing fluidic device includes a structure defining a common inflow channel, shared channel with a plurality of apertures, a plurality of recording chambers, a common return channel, and a plurality of control channels arranged to support a fluid flow within the structure. The plurality of control channels connects the common inflow channel to the shared channel and the plurality of recording chambers. The fluidic device includes a sealer configured to isolate the plurality of recording chambers from the plurality of control channels. A membrane is formed and coupled to each of the plurality of apertures, and a pore is inserted into each membrane. A sensor, coupled to each of the plurality of apertures, is configured to produce a representation of flow through each of the plurality of membrane pores.

Abstract: Systems and methods for controlled delivery of a specified quantity of particles. Systems involve a flow cell containing primary and secondary fluid chambers separated by a membrane, and a flow-producing module to induce particle translocation. Methods involve translocating particles between chambers through membrane activation, potentially for sorting and dispensing into target containers.