Patents by Inventor Ali Gilles Tchenguise Miserez

Ali Gilles Tchenguise Miserez has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230279061
    Abstract: The present invention relates to an isolated peptide modified based on the histidine-rich beak peptide (HBpep), which is derived from the Humbolt squid beak protein. In a preferred embodiment, the isolated peptide comprises the amino acid sequence of GHGVYGHGVYGHGPYKGHGPYGHGLYW (SEQ ID NO: 10), which contains a single lysine residue inserted at position 16 from the N-terminal of HBpep. In a further preferred embodiment, the lysine residue is conjugated with a self-immolative moiety, preferably comprising a disulfide moiety. The present invention also relates to a composition for the delivery of an active agent, wherein the composition comprises a peptide coace rvate comprising the isolated peptide and the active agent recruited in the peptide coace rvate. The present invention further relates to a method of recruiting the active agent in the peptide coace rvate, a method of delivering the active agent, and a method of treating or diagnosing a condition or disease in a subject.
    Type: Application
    Filed: June 1, 2021
    Publication date: September 7, 2023
    Inventors: Ali Gilles Tchenguise MISEREZ, Yue SUN
  • Publication number: 20220031627
    Abstract: The present invention provides for a composition, as disclosed herein, for delivery of an active agent. The composition includes a peptide coacervate, wherein the peptide coacervate includes one or more peptides derived from histidine-rich proteins, and an active agent encapsulated in the peptide coacervate. Further provided are a method for encapsulation of an active agent in a peptide coacervate, a method for delivery of an active agent, and a method for treating or diagnosing a condition or disease in a subject in need thereof.
    Type: Application
    Filed: October 20, 2021
    Publication date: February 3, 2022
    Inventors: Ali Gilles Tchenguise MISEREZ, Yuan PING, Zhi Wei LIM, Bartosz Piotr GABRYELCZYK
  • Publication number: 20220024979
    Abstract: The present invention, as disclosed herein, provides an isolated peptide, and a composition or material comprising a hydrogel, for the delivery of an active agent. The hydrogel comprises one or more isolated peptides and an active agent encapsulated in the hydrogel. The hydrogel is at least partially in a ?-sheet conformation. Further provided are a method for the encapsulation of an active agent in a hydrogel, a method for treating or diagnosing a condition or disease in a subject in need thereof.
    Type: Application
    Filed: June 30, 2021
    Publication date: January 27, 2022
    Inventors: Ali Gilles Tchenguise MISEREZ, Shu Hui HIEW, Chor Yong TAY, Jun Kit WANG
  • Patent number: 11179342
    Abstract: Described herein is a composition for delivery of an active agent. The composition includes a peptide coacervate, wherein the peptide coacervate includes one or more peptides derived from histidine-rich proteins, and an active agent encapsulated in the peptide coacervate. Further provided are a method for encapsulation of an active agent in a peptide coacervate, a method for delivery of an active agent, and a method for treating or diagnosing a condition or disease in a subject in need thereof.
    Type: Grant
    Filed: June 20, 2019
    Date of Patent: November 23, 2021
    Assignee: NANYANG TECHNOLOGICAL UNIVERSITY
    Inventors: Ali Gilles Tchenguise Miserez, Yuan Ping, Zhi Wei Lim, Bartosz Piotr Gabryelczyk
  • Patent number: 10899803
    Abstract: Sucker ring tooth (SRT) proteins called Suckerins were identified from the sucker tissue of three distantly related Decapodiformes species. These proteins assemble into silk-like beta-sheet reinforced materials. The use of suckerin proteins to produce fibres, films and tissue scaffolds is also described.
    Type: Grant
    Filed: October 17, 2013
    Date of Patent: January 26, 2021
    Assignees: Nanyang Technological University, Agency for Science, Technology and Researech
    Inventors: Paul Andre Guerette, Ali Gilles Tchenguise Miserez, Shawn Hoon
  • Publication number: 20190388357
    Abstract: The present invention provides for a composition, as disclosed herein, for delivery of an active agent. The composition includes a peptide coacervate, wherein the peptide coacervate includes one or more peptides derived from histidine-rich proteins, and an active agent encapsulated in the peptide coacervate. Further provided are a method for encapsulation of an active agent in a peptide coacervate, a method for delivery of an active agent, and a method for treating or diagnosing a condition or disease in a subject in need thereof.
    Type: Application
    Filed: June 20, 2019
    Publication date: December 26, 2019
    Inventors: Ali Gilles Tchenguise MISEREZ, Yuan PING, Zhi Wei LIM, Bartosz Piotr GABRYELCZYK
  • Publication number: 20150274789
    Abstract: Sucker ring tooth (SRT) proteins called Suckerins were identified from the sucker tissue of three distantly related Decapodiformes species. These proteins assemble into silk-like beta-sheet reinforced materials. The use of suckerin proteins to produce fibres, films and tissue scaffolds is also described.
    Type: Application
    Filed: October 17, 2013
    Publication date: October 1, 2015
    Applicants: Nanyang Technological University, Agency for Science, Technology and Research
    Inventors: Paul Andre Guerette, Ali Gilles Tchenguise Miserez, Shawn Hoon