Abstract: The present invention provides a method for assessing brain health in a subject, comprising the steps of administering one or more visual perception tests to the subject; obtaining a measurement of behavioural responses during the one or more visual perceptual tests and extracting indices of perceptual ability for each test from the behavioural responses; and/or obtaining a measurement of electrophysiological responses of the subject during administration of the one or more visual perception tests, and extracting indices from the electrophysiological responses for each task, wherein a time-based correlation of events occurring during the tests with the obtained electrophysiological responses is also obtained; and comparing the obtained behavioural indices, the obtained electrophysiological indices, or both with a comparative data set of healthy older adults with normal cognition, or a historical data set of the same individual, to identify deviations from normative or historical performance in any measure to

Abstract: A method for selecting a molecular target for therapeutic application involves accessing omic information and protein-protein interaction (PPI) data including a network of protein nodes. The method further involves computing a Gibbs free energy for each protein node within the network of protein nodes using the omic information and the PPI data, interpreting information for one or more products of gene fusion from the omic information as one or more gene fusion protein probabilities, and converting the one or more gene fusion protein probabilities into one or more gene fusion protein networks based on a Fermi distribution. The method also involves taking a union of the network of protein nodes with the one or more gene fusion protein networks and generating an energy landscape corresponding to the union of the network of protein nodes with the one or more gene fusion protein networks, and the Gibbs free energy.

Abstract: A method for therapeutic application involves accessing information associated with a patient and a reference biological network database, generating, using the information associated with the patient and the reference biological network database, a disease model, identifying, from the disease model, a molecular target, identifying, from the molecular target, a drug for the patient, generating, based on the drug for the patient, a treatment plan for the patient, and repetitively generating, based on repetitively inputting a patient outcome from the treatment plan into a feedback loop mechanism, a different treatment plan for the patient based on either the molecular target or a different molecular target.

Abstract: A device for scraping cells and tissues and methods of fabricating the same are disclosed herein.