Abstract: A method and system of providing private data privately when such data is requested from a VCD utilizes a communications network to communicate with a service containing the private data to determine if the data is private. Once the data is determined as being private, instead of being sent to the VCD to be broadcasted audibly, the data may be transmitted to a user's preferred device to be presented privately to the user.

Abstract: A method, apparatus and a system for thermally-assisted pulsed electromagnetic field stimulation for treatment of osteoarthritis in the knee are disclosed. A multi-coil applicator is adapted for positioning around the knee. A first coil is positioned on the top of the knee and provides electric field stimulation in the plane of the patella to stimulate the patella cartilage. Second and third coils are rectangular coils wrapped up below and above the knee respectively. The coils in the wrapped position generate a magnetic field along the knee axis and provide high amplitude of the electric field stimulation of the femoral and tibial cartilages in the plane of tibial plateau. Resistive heaters and free wheel diodes can be provided to the applicator to supply uniform thermal stimulation around the knee joint.

Abstract: Methods and apparatus for treatment of cancer are provided. The method can include systemic delivery of A3 selective adenosine receptor (A3AR) agonists CI-IB-MECA, cordycepin or similar drugs and providing simultaneous pulsed Electric Field (EF) stimulation to the treatment area. EF stimulation can be delivered in three orthogonal directions, which significantly increases expression of A3ARs on the cellular membranes and allows achieving a downstream apoptotic signal that is 4-6 fold stronger than the signal achieved with the agonist drugs alone.

Abstract: A method and apparatus for treatment of benign prostatic hyperplasia (BPH) are provided. The method includes providing a set of coils that generate multidirectional pulsed electromagnetic fields in the prostate. The apparatus comprises a power source, an intelligent controller and an applicator positioned in proximity to the prostate and generating multidirectional pulsed fields according to instructions from the controller. The electric component of the electromagnetic fields generated by a PEMF interacts with cells, increases the number of A2a receptors on their membranes and thus enhances the anti-inflammatory actions of the adenosine A2aAR pathway.

Abstract: A method for augmenting procedures at production equipment includes: linking a first description of a first step in a procedure and a capture type to a first capture field; generating a digital draft procedure comprising descriptions of steps extracted from the procedure and the first capture field specifying data capture of the first capture type from an equipment unit; generating augmented guidance for the first step in the procedure based on visual content recorded by a mobile device—assigned to an exemplary operator—during completion of the first step in the digital draft procedure; linking the augmented guidance to a location proximal the equipment unit based on locations of the first mobile device during completion of the first step in the digital draft procedure; and generating an augmented digital procedure based on steps in the procedure, the augmented guidance, and definitions for data capture according to the first capture field.

Abstract: A method for anti-inflammatory treatment of diabetic retinopathy can include systemic administration of an A2aAR agonist and providing local electric field stimulation to the retina. The electric field stimulation causes translocation of A2aRs from cytosol to the cell membranes and makes them active and available for binding with adenosine and adenosine agonists. Increased numbers of active A2aRs on cellular membranes leads to several-fold increase in the anti-inflammatory signal transduced into the cells. Amplified adenosine-A2aR signaling pathway causes significant inhibition of production of proinflammatory cytokines and other cytotoxic activity of microglia thus protecting the retina from destruction by the immune system and preserving eyesight. A treatment apparatus can include a multicoil applicator with coils adapted for positioning near eyes for stimulating retina, a pulse generator functionally coupled to the applicator and a power supply.

Abstract: A method and apparatus for treatment of cancer is provided. The method can include systemic delivery of A3 selective adenosine receptor (A3AR) agonists CI-IB-MECA, cordycepin or similar drugs and providing simultaneous pulsed Electric Field (EF) stimulation to the treatment area. EF stimulation can be delivered in three orthogonal directions, which significantly increases expression of A3ARs on the cellular membranes and allows achieving a downstream apoptotic signal that is 4-6 fold stronger than the signal achieved with the agonist drugs alone.

Abstract: A method for augmenting procedures at production equipment includes: linking a first description of a first step in a procedure and a capture type to a first capture field; generating a digital draft procedure comprising descriptions of steps extracted from the procedure and the first capture field specifying data capture of the first capture type from an equipment unit; generating augmented guidance for the first step in the procedure based on visual content recorded by a mobile device—assigned to an exemplary operator—during completion of the first step in the digital draft procedure; linking the augmented guidance to a location proximal the equipment unit based on locations of the first mobile device during completion of the first step in the digital draft procedure; and generating an augmented digital procedure based on steps in the procedure, the augmented guidance, and definitions for data capture according to the first capture field.

Abstract: Methods and apparatus for treatment of cancer are provided. The method can include systemic administration of selective A3 adenosine receptor (A3AR) agonists like CI-IB-MECA (CF 101), U-529, cordycepin or similar drugs in combination with application of pulsed Electric Field Stimulation (EFS) to the treatment area. A3AR agonists may be delivered in blend with allosteric enhancers of A3AR agonists potency like LUF6000 or other similar drugs. EFS is provided in three or more directions, which significantly increases expression of A3ARs on the cellular membranes and allows achieving a downstream apoptotic signal several-fold stronger than the signal created by an agonist alone. The apparatus may be dedicated to one patient usage over long period of time – hours and days continuously or intermittently.

Abstract: A method and apparatus for treatment of benign prostatic hyperplasia (BPH) are provided. The method includes providing a set of coils that generate multidirectional pulsed electromagnetic fields in the prostate. The apparatus comprises a power source, an intelligent controller and an applicator positioned in proximity to the prostate and generating multidirectional pulsed fields according to instructions from the controller. The electric component of the electromagnetic fields generated by a PEMF interacts with cells, increases the number of Ata receptors on their membranes and thus enhances the anti-inflammatory actions of the adenosine A2aAR pathway.

Abstract: A method for anti-inflammatory treatment of diabetic retinopathy can include systemic administration of an A2aAR agonist and providing local electric field stimulation to the retina. The electric field stimulation causes translocation of A2aRs from cytosol to the cell membranes and makes them active and available for binding with adenosine and adenosine agonists. Increased numbers of active A2aRs on cellular membranes leads to several-fold increase in the anti-inflammatory signal transduced into the cells. Amplified adenosine-A2aR signaling pathway causes significant inhibition of production of proinflammatory cytokines and other cytotoxic activity of microglia thus protecting the retina from destruction by the immune system and preserving eyesight. A treatment apparatus can include a multicoil applicator with coils adapted for positioning near eyes for stimulating retina, a pulse generator functionally coupled to the applicator and a power supply.

Abstract: A method includes: via a user interface of a hub device, receiving a first set of user credentials associated with a first operator, the hub device connected to a set of mobile devices; accessing a first operator schedule defining a first scheduled manufacturing operation and a first observer of the first scheduled manufacturing operation, the first observer characterized by a first set of observer credentials; detecting disconnection of a first mobile device in the set of mobile devices from the hub device, the first mobile device associated with a first device ID; in response to detecting disconnection of the first mobile device from the hub device, associating the first device ID with the first operator; and routing a first video feed from the first mobile device to the first observer based on the first device ID and the first set of observer credentials.

Abstract: A method and apparatus for treatment of cancer is provided. The method can include systemic administration of selective A3 adenosine receptor (A3AR) agonists like CI-IB-MECA (CF 101), LI-529, cordycepin or similar drugs in combination with application of pulsed Electric Field Stimulation (EFS) to the treatment area. A3AR agonists may be delivered in blend with allosteric enhancers of A3AR agonists potency like LUF6000 or other similar drugs. EFS is provided in three or more directions, which significantly increases expression of A3ARs on the cellular membranes and allows achieving a downstream apoptotic signal several-fold stronger than the signal created by an agonist alone. The apparatus may be dedicated to one patient usage over long period of time—hours and days continuously or intermittently.

Abstract: A method includes: via a user interface of a hub device, receiving a first set of user credentials associated with a first operator, the hub device connected to a set of mobile devices; accessing a first operator schedule defining a first scheduled manufacturing operation and a first observer of the first scheduled manufacturing operation, the first observer characterized by a first set of observer credentials; detecting disconnection of a first mobile device in the set of mobile devices from the hub device, the first mobile device associated with a first device ID; in response to detecting disconnection of the first mobile device from the hub device, associating the first device ID with the first operator; and routing a first video feed from the first mobile device to the first observer based on the first device ID and the first set of observer credentials.

Abstract: One variation of a method for controlling dissemination of instructional content to operators performing procedures at equipment within a facility includes: at a computing device, accessing a digital procedure containing a first instructional block comprising a first instruction in a set of formats including a text format corresponding to a first degree of guidance, an audio format corresponding to a second degree of guidance different from the first degree, and a visual format corresponding to a third degree of guidance greater than the first and second degrees; accessing a minimum instruction guidance specification for a current instance of the digital procedure; and, in response to initiation of the first instructional block in the digital procedure, presenting the first instruction in a particular format, in the set of formats, corresponding to a particular degree of guidance approximating the minimum instruction guidance specification.

Abstract: A method for augmenting procedures at production equipment includes: linking a first description of a first step in a procedure and a capture type to a first capture field; generating a digital draft procedure comprising descriptions of steps extracted from the procedure and the first capture field specifying data capture of the first capture type from an equipment unit; generating augmented guidance for the first step in the procedure based on visual content recorded by a mobile device—assigned to an exemplary operator—during completion of the first step in the digital draft procedure; linking the augmented guidance to a location proximal the equipment unit based on locations of the first mobile device during completion of the first step in the digital draft procedure; and generating an augmented digital procedure based on steps in the procedure, the augmented guidance, and definitions for data capture according to the first capture field.

Abstract: One variation of a method for controlling dissemination of instructional content to operators performing procedures at equipment within a facility includes: at a computing device, accessing a digital procedure containing a first instructional block comprising a first instruction in a set of formats including a text format corresponding to a first degree of guidance, an audio format corresponding to a second degree of guidance different from the first degree, and a visual format corresponding to a third degree of guidance greater than the first and second degrees; accessing a minimum instruction guidance specification for a current instance of the digital procedure; and, in response to initiation of the first instructional block in the digital procedure, presenting the first instruction in a particular format, in the set of formats, corresponding to a particular degree of guidance approximating the minimum instruction guidance specification.

Abstract: A method for augmenting procedures at production equipment includes: linking a first description of a first step in a procedure and a capture type to a first capture field; generating a digital draft procedure comprising descriptions of steps extracted from the procedure and the first capture field specifying data capture of the first capture type from an equipment unit; generating augmented guidance for the first step in the procedure based on visual content recorded by a mobile device—assigned to an exemplary operator—during completion of the first step in the digital draft procedure; linking the augmented guidance to a location proximal the equipment unit based on locations of the first mobile device during completion of the first step in the digital draft procedure; and generating an augmented digital procedure based on steps in the procedure, the augmented guidance, and definitions for data capture according to the first capture field.

Abstract: A method and apparatus for treatment of cancer is provided. The method can include systemic administration of selective A3 adenosine receptor (A3AR) agonists like CI-IB-MECA (CF 101), LI-529, cordycepin or similar drugs in combination with application of pulsed Electric Field Stimulation (EFS) to the treatment area. A3AR agonists may be delivered in blend with allosteric enhancers of A3AR agonists potency like LUF6000 or other similar drugs. EFS is provided in three or more directions, which significantly increases expression of A3ARs on the cellular membranes and allows achieving a downstream apoptotic signal several-fold stronger than the signal created by an agonist alone. The apparatus may be dedicated to one patient usage over long period of time—hours and days continuously or intermittently.

Abstract: A method includes: via a user interface of a hub device, receiving a first set of user credentials associated with a first operator, the hub device connected to a set of mobile devices; accessing a first operator schedule defining a first scheduled manufacturing operation and a first observer of the first scheduled manufacturing operation, the first observer characterized by a first set of observer credentials; detecting disconnection of a first mobile device in the set of mobile devices from the hub device, the first mobile device associated with a first device ID; in response to detecting disconnection of the first mobile device from the hub device, associating the first device ID with the first operator; and routing a first video feed from the first mobile device to the first observer based on the first device ID and the first set of observer credentials.