Abstract: An insulating housing shell for a miniature x-ray emitter is provided. The housing shell is cut from a quartz monocrystal which is a suitable material for the insulating housing shell due to its resistivity and dielectric strength properties. The x-ray emitter can be inserted into a subject's body to deliver x-ray radiation. The emitter includes a cable, having a proximal and a distal portion. The insulating housing shell is coupled to the distal portion of the cable, and an anode and a cathode are disposed within the insulating housing shell. The cathode has a granular surface and is operative with the anode and the connector to produce the x-ray radiation. The cathode is composed of a material that also allows it to act as a getter.

Abstract: An apparatus and method for stabilization of aneurysm is disclosed. The apparatus comprises an ultraviolet radiation generator for generating UV radiation having a wavelength, strongly absorbed by the DNA and a catheter including means for delivering the ultraviolet radiation to the aneurysm. The distal end of the catheter is placed inside the aneurysm. Stabilization of the aneurysm is achieved by forming a mural arterial thrombus inside the aneurysm. To make irradiation possible, the blood is displaced from the aneurysm by a steady stream of UV radiation transparent fluid. The injury to the endothelium that triggers the thrombus formation is caused by UV radiation delivered to the aneurysm. In several days after intervention the thrombus becomes fully organized, leaving on the inside surface of the aneurysm a thick layer of fibrotic tissue that stabilizes the aneurysm.

Abstract: This invention provides an apparatus and method for emergency administration or self-administration of thrombolytic therapy in early stage of a heart attack. The apparatus includes a needle injector for making a venipuncture, a battery operated micro cooler for maintaining low temperature environment for vials with lyophilized thrombolytic and adjuvant drugs, a container with a diluent for reconstitution of the lyophilized drugs, a programmable infusion pump, and a microprocessor for controlling the process of infusion and recording the data. As the system is activated, said container becomes fluidly communicable with the infusion pump and vials with drugs in the cooler. Designed for autonomous execution of several schedules of infusion, it also can be controlled remotely by a qualified operator via an Internet interface.

Abstract: A method of manufacturing an X-ray device is described including the step of coupling a housing that includes diamond to an anode structure that includes diamond. Further, a target metal may be formed on a tip of the anode structure. An X-ray device is also described including a housing made of diamond, a cathode within the housing, and an anode structure that includes diamond. The anode structure may include conductive diamond, while the housing structure may include high resistivity diamond.

Abstract: An apparatus and a method for reducing restenosis rate after balloon angioplasty is provided. The apparatus comprises a high voltage pulse generator and an intravascular catheter with electrodes adapted for delivery of electrical pulses to the media and adventitia of the treated segment of an artery. The amplitude, duration and number of the electrical pulses applied to the artery wall are sufficient to significantly deplete the population of smooth muscle cells, exuberant proliferation of which causes restenosis. To avoid possible fibrillation, the electric pulses are delivered during periods of depolarized state of myocardium.

Abstract: A method of manufacturing an X-ray device is described including the step of coupling a housing that includes diamond to an anode structure that includes diamond. Further, a target metal may be formed on a tip of the anode structure. An X-ray device is also described including a housing made of diamond, a cathode within the housing, and an anode structure that includes diamond. The anode structure may include conductive diamond, while the housing structure may include high resistivity diamond.

Abstract: An apparatus and method for exposing a treatment site in a patient to x-ray radiation is described that uses a pulse voltage source, where the x-ray emitter employs a cold cathode. The invention may further include a current sensor for measuring a current through the x-ray emitter, and, optionally, a current integrator connected to the current sensor. Each voltage pulse may be discontinued when a predetermined amount of charge has passed through the emitter. The step of moving an x-ray emitter past a treatment area at a rate determined by the amount of charge that has passed through the emitter is also described. The present invention also includes an x-ray emitter device with rectangular voltage pulses added to a base direct current voltage. Another step of the invention may be applying a voltage pulse cycle to the x-ray emitter where a duration of the pulse is 2-5 times lower than a thermal relaxation time of an emitter.