Patents by Inventor Ali Khamene

Ali Khamene has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9681925
    Abstract: A system and method for instrument placement using an image based navigation system is disclosed. A target of interest is identified in a medical image of a patient. An image plane is displayed that goes through a center of the target. The image plane has a configurable orientation. The image plane is used to select a path for an instrument from a position on the patient's skin to the center of the target. A trajectory plane is viewed from a tip of the instrument to the center of the target. The trajectory plane reflects an orientation of the instrument. A particular trajectory plane is selected that is representative of a desired orientation of the instrument. An image of the particular trajectory plane is frozen. The instrument can then be inserted using a virtual guide and is navigated toward the target.
    Type: Grant
    Filed: April 15, 2005
    Date of Patent: June 20, 2017
    Assignee: SIEMENS MEDICAL SOLUTIONS USA, INC.
    Inventors: Fred S. Azar, Ali Khamene, Frank Sauer, Sebastian Vogt
  • Patent number: 9289267
    Abstract: A method and apparatus for presenting three-dimensional data to a physician is provided to facilitate the flexible navigation of an endoscope and surgical instruments with respect to anatomical structures. In accordance with a first embodiment a first set of data corresponding to a three dimensional model of a patient's anatomy is received. This three-dimensional model may be rendered from images taken in CT or MRI scanning, as discussed above. In accordance with this embodiment, this model is then combined with a second set of data corresponding to a view obtained from an endoscope. In another embodiment, the view from the illustrative endoscope is displayed as an inset image on the display of the three-dimensional image. In yet another embodiment, the three-dimensional image comprises a graphical representation of at least a first surgical instrument, such as said endoscope. The surgeon may select among various combinations of views and may zoom in or out from any particular view.
    Type: Grant
    Filed: May 16, 2006
    Date of Patent: March 22, 2016
    Assignee: SIEMENS MEDICAL SOLUTIONS USA, INC.
    Inventors: Frank Sauer, Ali Khamene, Sebastian Vogt
  • Patent number: 8271068
    Abstract: A method of determining a three-dimensional (3D) position of a catheter tip includes: compensating a 2D position of the tip of the catheter for respiratory motion to generate a compensated 2D catheter position, generating weighted sample points around the compensated 2D catheter position, determining correspondent points of the weighted sample points in a 3D image, computing a weighted mean and a weighted covariance of each correspondent point, and determining the 3D position of the catheter tip in the 3D image from a fusion of the weighted means and weighted covariances.
    Type: Grant
    Filed: October 1, 2008
    Date of Patent: September 18, 2012
    Assignee: Siemens Aktiengesellschaft
    Inventors: Ali Khamene, Frederik Bender, Wolfgang Wein
  • Patent number: 8244332
    Abstract: A diffuse optical spectroscopy system comprises a laser breast scanner, a handheld probe connected to the laser breast scanner for scanning a breast, and a tracking device coupled to the handheld probe, wherein the tracking device determines locations of the handheld probe relative to the breast. The tracking device comprises a magnetic tracking device, an optical tracking device or a laser tracking device.
    Type: Grant
    Filed: December 1, 2005
    Date of Patent: August 14, 2012
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Fred S. Azar, Ali Khamene, Frank Sauer, Bruce Tromberg, Albert Cerussi
  • Patent number: 8218909
    Abstract: A method for deformable registration of 2 digital images includes providing a pair of digital images, including a fixed image and a moving image, extracting a set of edge images from each image of the pair of images, each edge set being extracted at a different resolution, selecting a pair of edge images with a lowest resolution, determining a mapping from edge points of the fixed image to edge points of moving image using a geodesic thin plate spline interpolation, applying the mapping to a next higher resolution edge point image of the moving image, selecting a pair of edge images at a next higher resolution, where a moving edge image is the moving edge image to which the mapping has been applied, repeating the steps at a next higher resolution for all edge images in the set of edge images, and applying the mapping to an entire moving image.
    Type: Grant
    Filed: August 26, 2008
    Date of Patent: July 10, 2012
    Assignee: Siemens Aktiengesellschaft
    Inventors: Ali Khamene, Fabrice Michel
  • Patent number: 8184886
    Abstract: A method for deformable registration including determining a vector field from a two-dimensional matching of a volume of an object of interest and a two-dimensional image of the object of interest, providing a deformation profile, and finding a volume deformation that maps to a state of the two-dimensional image, wherein the deformation is parameterized by the vector field and control points of the deformation profile to find a control point configuration of the volume deformation.
    Type: Grant
    Filed: August 15, 2008
    Date of Patent: May 22, 2012
    Assignee: Siemens Aktiengesellschaft
    Inventors: Ali Khamene, Oliver Fluck, Shmuel Aharon
  • Patent number: 8139831
    Abstract: A method for unsupervised classification of histological images of prostatic tissue includes providing histological image data obtained from a slide simultaneously co-stained with NIR fluorescent and Hematoxylin-and-Eosin (H&E) stains, segmenting prostate gland units in the image data, forming feature vectors by computing discriminating attributes of the segmented gland units, and using the feature vectors to train a multi-class classifier, where the classifier classifies prostatic tissue into benign, prostatic intraepithelial neoplasia (PIN), and Gleason scale adenocarcinoma grades 1 to 5 categories.
    Type: Grant
    Filed: December 2, 2008
    Date of Patent: March 20, 2012
    Assignee: Siemens Aktiengesellschaft
    Inventors: Ali Khamene, Tina Ehtiati, John V. Frangioni, Vida Kianzad, Fred S. Azar
  • Patent number: 8073220
    Abstract: Methods and systems dedicated to automatic object segmentation from image data are provided. In a first step a fuzzy seed set is generated that is learned from training data. The fuzzy seed set is registered to image data containing an object that needs to be segmented from a background. In a second step a random walker segmentation is applied to the image data by using the fuzzy seed set as an automatic seeding for segmentation. Liver segmentation, lung segmentation and kidney segmentation examples are provided.
    Type: Grant
    Filed: April 20, 2009
    Date of Patent: December 6, 2011
    Assignee: Siemens Aktiengesellschaft
    Inventors: Ali Khamene, Leo Grady, Eike Rietzel, Thomas Boettger
  • Publication number: 20110130645
    Abstract: A method for reconstructing an ear canal from optical coherence tomography (OCT) scan data of an ear comprises extracting frame numbers and line numbers of interference intensities corresponding to one or more markers on an OCT scan guide, receiving reference frame numbers and lines numbers for one or more markers, determining a starting position and direction for the OCT ear scan from the ear scan marker frame and line numbers and the reference marker frame and line numbers, for each scan line, finding a pixel number of a maximum interference intensity value, and determining an offset distance of said pixel from said scan guide, and reconstructing a surface of the ear canal from the distance offset data.
    Type: Application
    Filed: April 17, 2006
    Publication date: June 2, 2011
    Inventors: Ali Khamene, Martin Masters, Frank Sauer, Therese Velde
  • Patent number: 7949385
    Abstract: A method for reconstructing an ear canal from optical coherence tomography (OCT) scan data of an ear comprises extracting frame numbers and line numbers of interference intensities corresponding to one or more markers on an OCT scan guide, receiving reference frame numbers and lines numbers for one or more markers, determining a starting position and direction for the OCT ear scan from the ear scan marker frame and line numbers and the reference marker frame and line numbers, for each scan line, finding a pixel number of a maximum interference intensity value, and determining an offset distance of said pixel from said scan guide, and reconstructing a surface of the ear canal from the distance offset data.
    Type: Grant
    Filed: April 17, 2006
    Date of Patent: May 24, 2011
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Ali Khamene, Martin W. Masters, Frank Sauer, Therese Velde
  • Patent number: 7940999
    Abstract: A method of registering 3-dimensional digitized images to 2-dimensional digitized images during a medical procedure includes providing a pair of correctly-registered training images L={lr, lf} and their joint intensity distribution pl(ir, if), wherein ir and if are reference and floating images, respectively, providing a pair of observed images O={or, of} and their joint intensity distribution po(ir, if), mapping a marginal intensity distribution of the observed pair O={or, of} to a marginal intensity distribution of the training pair L={lr, lf}, and estimating a set of parameters T that registers image of to image or by maximizing a weighted sum of a Jensen-Shannon divergence (JSD) of a joint intensity distribution of the observed pair and a joint intensity distribution of the training pair and a similarity measure between the observed images.
    Type: Grant
    Filed: March 15, 2007
    Date of Patent: May 10, 2011
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Rui Liao, Christoph Guetter, Chenyang Xu, Yiyong Sun, Ali Khamene, Frank Sauer
  • Patent number: 7920144
    Abstract: A method for visualization of dynamic three-dimensional (3D) virtual objects comprises storing a plurality of static 3D key-models respectively describing a dynamic 3D object in at least one of a number of poses and shapes; and rendering the dynamic 3D object by interpolation of the 3D key-models by performing the interpolation in a vertex shader program of a programmable graphics processing unit (GPU).
    Type: Grant
    Filed: January 10, 2006
    Date of Patent: April 5, 2011
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Sebastian Vogt, Frank Sauer, Ali Khamene
  • Patent number: 7869562
    Abstract: A patient positioning system for positioning a patient relative to radiographic equipment. The system includes: a 3D optical imaging system for optically scanning the patient, such 3D optical imaging system having a focal plane and providing, for each position on the object, data representative of the intensity of reflected energy received by the system from such position and data representative of distance from such position on the object to the focal plane; a table apparatus for supporting the patient and for moving the table relative to the radiographic equipment in response to positioning signals; and a processor responsive to data from the radiographic equipment and the data from the a 3D optical imaging system for producing the positioning signals. The system enables a method for displaying temporal changes in a patient positioned with a bore of radiographic equipment.
    Type: Grant
    Filed: March 18, 2009
    Date of Patent: January 11, 2011
    Assignee: Siemens Aktiengesellschaft
    Inventors: Ali Khamene, Stefan K├Ąpplinger, Gabriel Haras, Eike Rietzel
  • Patent number: 7853308
    Abstract: A system and method for positioning a patient for radiotherapy is provided. The method comprises: acquiring a first x-ray image sequence of a target inside the patient at a first angle; acquiring first respiratory signals of the patient while acquiring the first x-ray image sequence; acquiring a second x-ray image sequence of the target at a second angle; acquiring second respiratory signals of the patient while acquiring the second x-ray image sequence; synchronizing the first and second x-ray image sequences with the first and second respiratory signals to form synchronized first and second x-ray image sequences; identifying the target in the synchronized first and second x-ray image sequences; and determining three-dimensional (3D) positions of the target through time in the synchronized first and second x-ray image sequences.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: December 14, 2010
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Frank Sauer, Ali Khamene
  • Publication number: 20100266170
    Abstract: Methods and systems dedicated to automatic object segmentation from image data are provided. In a first step a fuzzy seed set is generated that is learned from training data. The fuzzy seed set is registered to image data containing an object that needs to be segmented from a background. In a second step a random walker segmentation is applied to the image data by using the fuzzy seed set as an automatic seeding for segmentation. Liver segmentation, lung segmentation and kidney segmentation examples are provided.
    Type: Application
    Filed: April 20, 2009
    Publication date: October 21, 2010
    Applicant: Siemens Corporate Research, Inc.
    Inventors: Ali Khamene, Leo Grady, Eike Rietzel, Thomas Boettger
  • Patent number: 7787683
    Abstract: A system and method for tree structure based two-dimensional to three-dimensional registration are provided for receiving three-dimensional (3D) data indicative of vessels, segmenting the 3D data with a vessel tree, simulating two-dimensional (2D) data responsive to the segmented 3D data to form a simulated 2D image, receiving 2D data indicative of vessels, segmenting the received 2D data with a vessel tree, finding a distance transform of the segmented 2D data to form a 2D distance map image, considering a set of poses as state vectors with the corresponding probability computed using the similarity measure computation, re-sampling the pose vector to find a set of most probable poses and considering them as hypothesized poses, recomputing the projection and re-evaluating the probability of the hypothesized poses and updating the state vector until the optimal pose is found.
    Type: Grant
    Filed: December 16, 2005
    Date of Patent: August 31, 2010
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Ali Khamene, Charles Florin, Frank Sauer, James P. Williams
  • Patent number: 7774044
    Abstract: A method for augmented reality navigation of a medical intervention includes providing a stereoscopic head mounted display, the display including a pair of stereo viewing cameras, at least one tracking camera, and a stereoscopic guidance display. During a medical intervention on a patient, the patient's body pose is determined from a rigid body transformation between the tracking camera and frame markers on the scanning table, and the pose of an intervention instrument with respect to the table is determined. A visual representation of the patient overlaid with an image of the intervention target, the instrument, and a path for guiding the instrument to perform said medical intervention is displayed in the stereoscopic guidance display.
    Type: Grant
    Filed: February 11, 2005
    Date of Patent: August 10, 2010
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Frank Sauer, Ali Khamene, Sebastian Vogt
  • Patent number: 7724943
    Abstract: Exemplary methods are provided. In one exemplary method, a lower-dimension signature is generated for each of a plurality of data sets of a given dimension. Registration is performed on the lower-dimension signatures. In another exemplary method, a two-dimensional signature is generated for each of a plurality of three-dimensional volumes. Registration is performed on the two-dimensional signatures.
    Type: Grant
    Filed: April 19, 2005
    Date of Patent: May 25, 2010
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Ali Khamene, Frank Sauer, Chenyang Xu
  • Patent number: 7711405
    Abstract: A system and method for registering pre-operative magnetic resonance (MR) images with intra-operative MR images is disclosed. A pre-operative MR image of an object is received. A set of intra-operative MR images of the object is received. The pre-operative MR image is rigidly registered with the initial intra-operative MR image. The subsequent set of intra-operative images is deformably registered. The pre-operative MR image undergoes both rigid and deformation transformation to match specification of each image with in intra-operative MR image set.
    Type: Grant
    Filed: April 28, 2004
    Date of Patent: May 4, 2010
    Assignee: Siemens Corporation
    Inventors: Ali Khamene, Frank Sauer
  • Patent number: 7677078
    Abstract: Apparatus for calibrating an ultrasound transducer providing B-scans for two-dimensional (2D) images, includes: an ultrasound probe for providing B-scans; a position sensing device, the position sensing device being attached to the ultrasound probe and operating as part of a position sensing system in cooperation with a fixed sensing control unit, for labeling the B-scans with their respective relative positions and orientations (pose); a phantom marker for being imaged by the ultrasound probe for providing measurements which together with known physical properties of the phantom marker are used to derive calibration information for relating measurement data from the position sensing device to the poses of the B-scans to construct a 3D image; and the phantom marker comprising an encoded line object with distinctive calibration characteristics indicative of position along the line object, wherein the line object is disposed in a generally circumferential manner about a common axis with the probe.
    Type: Grant
    Filed: January 3, 2007
    Date of Patent: March 16, 2010
    Assignee: Siemens Medical Solutions USA, Inc.
    Inventors: Frank Sauer, Ali Khamene, Oliver Kutter, Sebastian Kassner